| | Other Issues: previous | next | latest | archiveSpotlight Articles of Significant Interest Selected from This Issue by the Editors PMCID: PMC2519594 Structure and Assembly The Envelope of Intracellular African Swine Fever Virus Is Composed of a Single Lipid Bilayer Philippa C. Hawes, Christopher L. Netherton, Thomas E. Wileman, and Paul Monaghan PMCID: PMC2519565 Mutagenesis and Nuclear Magnetic Resonance Analyses of the Fusion Peptide of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus F Protein Ying Tan, Ling Jiang, Manli Wang, Feifei Yin, Fei Deng, Maili Liu, Zhihong Hu, and Hualin Wang PMCID: PMC2519578 Genome Replication and Regulation of Viral Gene Expression Sf29 Gene of Spodoptera frugiperda Multiple Nucleopolyhedrovirus Is a Viral Factor That Determines the Number of Virions in Occlusion Bodies Oihane Simón, Trevor Williams, Aaron C. Asensio, Sarhay Ros, Andrea Gaya, Primitivo Caballero, and Robert D. Possee PMCID: PMC2519577 Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles Takahiro Masaki, Ryosuke Suzuki, Kyoko Murakami, Hideki Aizaki, Koji Ishii, Asako Murayama, Tomoko Date, Yoshiharu Matsuura, Tatsuo Miyamura, Takaji Wakita, and Tetsuro Suzuki PMCID: PMC2519576 The Secondary Structure of the Human Immunodeficiency Virus Type 1 Transcript Modulates Viral Splicing and Infectivity Joseph A. Jablonski, Emanuele Buratti, Cristiana Stuani, and Massimo Caputi PMCID: PMC2519558 Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2′O)-Methyltransferase Activity Etienne Decroly, Isabelle Imbert, Bruno Coutard, Mickaël Bouvet, Barbara Selisko, Karine Alvarez, Alexander E. Gorbalenya, Eric J. Snijder, and Bruno Canard PMCID: PMC2519555 Functional Characterization of the Cleavage Specificity of the Sapovirus Chymotrypsin-Like Protease Ivonne Robel, Julia Gebhardt, Jeroen R. Mesters, Alexander Gorbalenya, Bruno Coutard, Bruno Canard, Rolf Hilgenfeld, and Jacques Rohayem PMCID: PMC2519560 Liver-Specific MicroRNA miR-122 Enhances the Replication of Hepatitis C Virus in Nonhepatic Cells Jinhong Chang, Ju-Tao Guo, Dong Jiang, Haitao Guo, John M. Taylor, and Timothy M. Block PMCID: PMC2519557 Genetic Diversity and Evolution Phylogenetic and Genetic Analysis of Feline Immunodeficiency Virus gag, pol, and env Genes from Domestic Cats Undergoing Nucleoside Reverse Transcriptase Inhibitor Treatment or Treatment-Naïve Cats in Rio de Janeiro, Brazil Angelica N. Martins, Sheila O. Medeiros, Jose P. Simonetti, Hermann G. Schatzmayr, Amílcar Tanuri, and Rodrigo M. Brindeiro PMCID: PMC2519550 Human Immunodeficiency Virus (HIV) Type 1 Proviral Hypermutation Correlates with CD4 Count in HIV-Infected Women from Kenya Allison M. Land, T. Blake Ball, Ma Luo, Richard Pilon, Paul Sandstrom, Joanne E. Embree, Charles Wachihi, Joshua Kimani, and Francis A. Plummer PMCID: PMC2519552 Virus-Cell Interactions Competition Model for Upregulation of the Major Histocompatibility Complex Class II-Associated Invariant Chain by Human Immunodeficiency Virus Type 1 Nef Richard S. Mitchell, Rittik Chaudhuri, O. Wolf Lindwasser, Kristie A. Tanaka, David Lau, Rudy Murillo, Juan S. Bonifacino, and John C. Guatelli PMCID: PMC2519569 Properties of Subviral Particles of Hepatitis B Virus Ning Chai, Ho Eun Chang, Emmanuelle Nicolas, Ziying Han, Michal Jarnik, and John Taylor PMCID: PMC2519590 Structural Variations in Species B Adenovirus Fibers Impact CD46 Association Lars Pache, Sangita Venkataraman, Vijay S. Reddy, and Glen R. Nemerow PMCID: PMC2519554 A Novel Cellular Protein, VPEF, Facilitates Vaccinia Virus Penetration into HeLa Cells through Fluid Phase Endocytosis Cheng-Yen Huang, Tsai-Yi Lu, Chi-Horng Bair, Yuan-Shau Chang, Jeng-Kuan Jwo, and Wen Chang PMCID: PMC2519564 Structural Insights into Calicivirus Attachment and Uncoating David Bhella, Derek Gatherer, Yasmin Chaudhry, Rebecca Pink, and Ian G. Goodfellow PMCID: PMC2519574 Effects of Lamin A/C, Lamin B1, and Viral US3 Kinase Activity on Viral Infectivity, Virion Egress, and the Targeting of Herpes Simplex Virus UL34-Encoded Protein to the Inner Nuclear Membrane Fan Mou, Elizabeth G. Wills, Richard Park, and Joel D. Baines PMCID: PMC2519571 Mouse Hepatitis Virus Type 2 Enters Cells through a Clathrin-Mediated Endocytic Pathway Independent of Eps15 Yinghui Pu and Xuming Zhang PMCID: PMC2519582 Epstein-Barr Virus Latent Membrane Protein 1 Represses DNA Repair through the PI3K/Akt/FOXO3a Pathway in Human Epithelial Cells Yi-Ren Chen, Ming-Tsan Liu, Yu-Ting Chang, Chung-Chun Wu, Chi-Yuan Hu, and Jen-Yang Chen PMCID: PMC2519561 Structural Analysis Reveals an Amyloid Form of the Human Papillomavirus Type 16 E1∧E4 Protein and Provides a Molecular Basis for Its Accumulation Pauline B. McIntosh, Stephen R. Martin, Deborah J. Jackson, Jameela Khan, Erin R. Isaacson, Lesley Calder, Kenneth Raj, Heather M. Griffin, Qian Wang, Peter Laskey, John F. Eccleston, and John Doorbar PMCID: PMC2519553 Amino Acid 226 in the Hemagglutinin of H4N6 Influenza Virus Determines Binding Affinity for α2,6-Linked Sialic Acid and Infectivity Levels in Primary Swine and Human Respiratory Epithelial Cells Allen C. Bateman, Marc G. Busch, Alexander I. Karasin, Nicolai Bovin, and Christopher W. Olsen PMCID: PMC2519589 Deoxynucleoside Triphosphate Incorporation Mechanism of Foamy Virus (FV) Reverse Transcriptase: Implications for Cell Tropism of FV Jose Santos-Velazquez and Baek Kim PMCID: PMC2519572 Cellular Response to Infection Human Parvovirus B19 NS1 Protein Modulates Inflammatory Signaling by Activation of STAT3/PIAS3 in Human Endothelial Cells Anja Duechting, Carsten Tschöpe, Heike Kaiser, Tobias Lamkemeyer, Nobuyuki Tanaka, Susanne Aberle, Florian Lang, Joseph Torresi, Reinhard Kandolf, and C.-Thomas Bock PMCID: PMC2519586 Cellular La Protein Shields Nonsegmented Negative-Strand RNA Viral Leader RNA from RIG-I and Enhances Virus Growth by Diverse Mechanisms Vira Bitko, Alla Musiyenko, Mark A. Bayfield, Richard J. Maraia, and Sailen Barik PMCID: PMC2519562 Murine Gammaherpesvirus 68 Open Reading Frame 75c Tegument Protein Induces the Degradation of PML and Is Essential for Production of Infectious Virus Paul D. Ling, Jie Tan, Jaturong Sewatanon, and RongSheng Peng PMCID: PMC2519593 Role of Interferon in the Replication of Human Parainfluenza Virus Type 1 Wild Type and Mutant Viruses in Human Ciliated Airway Epithelium Emmalene J. Bartlett, Margaret Hennessey, Mario H. Skiadopoulos, Alexander C. Schmidt, Peter L. Collins, Brian R. Murphy, and Raymond J. Pickles PMCID: PMC2519580 Human Metapneumovirus Small Hydrophobic Protein Inhibits NF-κB Transcriptional Activity Xiaoyong Bao, Deepthi Kolli, Tianshuang Liu, Yichu Shan, Roberto P. Garofalo, and Antonella Casola PMCID: PMC2519579 Transformation and Oncogenesis Cross Talk between Expression of the Human T-Cell Leukemia Virus Type 1 Tax Transactivator and the Oncogenic bHLH Transcription Factor TAL1 Jean-Michel Terme, Melanie Wencker, Arnaud Favre-Bonvin, Françoise Bex, Louis Gazzolo, Madeleine Duc Dodon, and Pierre Jalinot PMCID: PMC2519563 Gene Delivery The Core Element of a CpG Island Protects Avian Sarcoma and Leukosis Virus-Derived Vectors from Transcriptional Silencing Filip Šenigl, Jiří Plachý, and Jiří Hejnar PMCID: PMC2519551 Adeno-Associated Virus Vector Genomes Persist as Episomal Chromatin in Primate Muscle Magalie Penaud-Budloo, Caroline Le Guiner, Ali Nowrouzi, Alice Toromanoff, Yan Chérel, Pierre Chenuaud, Manfred Schmidt, Christof von Kalle, Fabienne Rolling, Philippe Moullier, and Richard O. Snyder PMCID: PMC2519600 Vaccines and Antiviral Agents Zinc Finger Proteins Designed To Specifically Target Duck Hepatitis B Virus Covalently Closed Circular DNA Inhibit Viral Transcription in Tissue Culture Kimberley A. Zimmerman, Karl P. Fischer, Michael A. Joyce, and D. Lorne J. Tyrrell PMCID: PMC2519588 Disparity between Levels of In Vitro Neutralization of Vaccinia Virus by Antibody to the A27 Protein and Protection of Mice against Intranasal Challenge Christiana N. Fogg, Jeffrey L. Americo, Patricia L. Earl, Wolfgang Resch, Lydia Aldaz-Carroll, Roselyn J. Eisenberg, Gary H. Cohen, and Bernard Moss PMCID: PMC2519570 DNA gag/Adenovirus Type 5 (Ad5) gag and Ad5 gag/Ad5 gag Vaccines Induce Distinct T-Cell Response Profiles Kara S. Cox, James H. Clair, Michael T. Prokop, Kara J. Sykes, Sheri A. Dubey, John W. Shiver, Michael N. Robertson, and Danilo R. Casimiro PMCID: PMC2519591 In Vivo Emergence of Vicriviroc Resistance in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Subject Athe M. N. Tsibris, Manish Sagar, Roy M. Gulick, Zhaohui Su, Michael Hughes, Wayne Greaves, Mani Subramanian, Charles Flexner, Françoise Giguel, Kay E. Leopold, Eoin Coakley, and Daniel R. Kuritzkes PMCID: PMC2519584 Pathogenesis and Immunity A Simple Mathematical Model Helps To Explain the Immunodominance of CD8 T Cells in Influenza A Virus Infections Andreas Handel and Rustom Antia PMCID: PMC2519595 Virological Consequences of Early Events following Cell-Cell Contact between Human Immunodeficiency Virus Type 1-Infected and Uninfected CD4+ Cells Eliana Ruggiero, Roberta Bona, Claudia Muratori, and Maurizio Federico PMCID: PMC2519596 Human Immunodeficiency Virus Infection Alters Tumor Necrosis Factor Alpha Production via Toll-Like Receptor-Dependent Pathways in Alveolar Macrophages and U1 Cells Marlynne Q. Nicol, Jean-Marie Mathys, Albertina Pereira, Kevin Ollington, Michael H. Ieong, and Paul R. Skolnik PMCID: PMC2519548 Regulation of Cytokine Production by Virus-Specific CD8 T Cells in the Lungs Ross B. Fulton, Matthew R. Olson, and Steven M. Varga PMCID: PMC2519597 The Large Polymerase Protein Is Associated with the Virulence of Newcastle Disease Virus Subrat N. Rout and Siba K. Samal PMCID: PMC2519556 Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection Wei Jiang, Michael M. Lederman, Richard J. Mohner, Benigno Rodriguez, Todd M. Nedrich, Clifford V. Harding, and Scott F. Sieg PMCID: PMC2519583 A Single N-Linked Glycosylation Site in the Japanese Encephalitis Virus prM Protein Is Critical for Cell Type-Specific prM Protein Biogenesis, Virus Particle Release, and Pathogenicity in Mice Jeong-Min Kim, Sang-Im Yun, Byung-Hak Song, Youn-Soo Hahn, Chan-Hee Lee, Hyun-Woo Oh, and Young-Min Lee PMCID: PMC2519568 Dendritic Cells Preferentially Transfer CXCR4-Using Human Immunodeficiency Virus Type 1 Variants to CD4+ T Lymphocytes in trans Thijs van Montfort, Adri A. M. Thomas, Georgios Pollakis, and William A. Paxton PMCID: PMC2519566 Autologous Neutralizing Humoral Immunity and Evolution of the Viral Envelope in the Course of Subtype B Human Immunodeficiency Virus Type 1 Infection Evelien M. Bunnik, Linaida Pisas, Ad C. van Nuenen, and Hanneke Schuitemaker PMCID: PMC2519599 Replication Properties of Clade A/C Chimeric Feline Immunodeficiency Viruses and Evaluation of Infection Kinetics in the Domestic Cat Sohela de Rozìeres, Jesse Thompson, Magnus Sundstrom, Julia Gruber, Debora S. Stump, Aymeric P. de Parseval, Sue VandeWoude, and John H. Elder PMCID: PMC2519559 Influenza Virus Infection Augments NK Cell Inhibition through Reorganization of Major Histocompatibility Complex Class I Proteins Hagit Achdout, Irit Manaster, and Ofer Mandelboim PMCID: PMC2519585 In Vivo Potential Effects of Adenovirus Type 5 E1A and E1B on Lung Carcinogenesis and Lymphoproliferative Inflammation Yongping Yang, Colin McKerlie, Zhan Lu, Lena Wang, and Manuel Buchwald PMCID: PMC2519581 Effective Chemokine Secretion by Dendritic Cells and Expansion of Cross-Presenting CD4−/CD8+ Dendritic Cells Define a Protective Phenotype in the Mouse Model of Coxsackievirus Myocarditis Andreas Oliver Weinzierl, Gudrun Szalay, Hartwig Wolburg, Martina Sauter, Hans-Georg Rammensee, Reinhard Kandolf, Stefan Stevanović, and Karin Klingel PMCID: PMC2519575 Previously Infected Chimpanzees Are Not Consistently Protected against Reinfection or Persistent Infection after Reexposure to the Identical Hepatitis C Virus Strain Jens Bukh, Robert Thimme, Jean-Christophe Meunier, Kristina Faulk, Hans Christian Spangenberg, Kyong-Mi Chang, William Satterfield, Francis V. Chisari, and Robert H. Purcell PMCID: PMC2519567 The High Prevalence of Herpes Simplex Virus Type 1 DNA in Human Trigeminal Ganglia Is Not a Function of Age or Gender James M. Hill, Melvyn J. Ball, Donna M. Neumann, Ann M. Azcuy, Partha S. Bhattacharjee, Saadallah Bouhanik, Christian Clement, Walter J. Lukiw, Timothy P. Foster, Manish Kumar, Herbert E. Kaufman, and Hilary W. Thompson PMCID: PMC2519549 Letters to the Editor The First Chinese Porcine Sapovirus Strain That Contributed to an Outbreak of Gastroenteritis in Piglets Wen Zhang, Quan Shen, Xiuguo Hua, Li Cui, Junfeng Liu, and Shixing Yang PMCID: PMC2519573 When Should “I” Consider a New Hepatitis B Virus Genotype? Fuat Kurbanov, Yasuhito Tanaka, Anna Kramvis, Peter Simmonds, and Masashi Mizokami PMCID: PMC2519592 Errata Measles Virus Structural Components Are Enriched into Lipid Raft Microdomains: a Potential Cellular Location for Virus Assembly Serge N. Manié, Sylvain de Breyne, Séverine Vincent, and Denis Gerlier PMCID: PMC2519587 Corrects:Serge N. Manié, et al. Measles Virus Structural Components Are Enriched into Lipid Raft Microdomains: a Potential Cellular Location for Virus Assembly. J Virol. 2000 January; 74(1): 305–311. Potential Transmission of Human Polyomaviruses through the Gastrointestinal Tract after Exposure to Virions or Viral DNA Sílvia Bofill-Mas, Meritxell Formiga-Cruz, Pilar Clemente-Casares, Francesc Calafell, and Rosina Girones PMCID: PMC2519598 Corrects:Sílvia Bofill-Mas, et al. Potential Transmission of Human Polyomaviruses through the Gastrointestinal Tract after Exposure to Virions or Viral DNA. J Virol. 2001 November; 75(21): 10290–10299. |
