| | This journal provides immediate access to some articles. Other Issues: previous | next | latest | archiveIn This Issue J Clin Invest. 2009 January 5; 119(1): 1. Published online 2009 January 5. doi: 10.1172/JCI38132.PMCID: PMC2613465 Research Articles Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin Irini Bournazou, John D. Pound, Rodger Duffin, Stylianos Bournazos, Lynsey A. Melville, Simon B. Brown, Adriano G. Rossi, and Christopher D. Gregory PMCID: PMC2613454 TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4 Toshihiro Ito, Matthew Schaller, Cory M. Hogaboam, Theodore J. Standiford, Matyas Sandor, Nicholas W. Lukacs, Stephen W. Chensue, and Steven L. Kunkel PMCID: PMC2613456 IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice Haoli Jin, Michiko K. Oyoshi, Yi Le, Teresa Bianchi, Suresh Koduru, Clinton B. Mathias, Lalit Kumar, Séverine Le Bras, Deborah Young, Mary Collins, Michael J. Grusby, Joerg Wenzel, Thomas Bieber, Marianne Boes, Leslie E. Silberstein, Hans C. Oettgen, and Raif S. Geha PMCID: PMC2613448 IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice Stefan Haak, Andrew L. Croxford, Katharina Kreymborg, Frank L. Heppner, Sandrine Pouly, Burkhard Becher, and Ari Waisman PMCID: PMC2613466 Rare loss-of-function mutations in ANGPTL family members
contribute to plasma triglyceride levels in humans Stefano Romeo, Wu Yin, Julia Kozlitina, Len A. Pennacchio, Eric Boerwinkle, Helen H. Hobbs, and Jonathan C. Cohen PMCID: PMC2613476 Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes
Christophe A. Girard, F. Thomas Wunderlich, Kenju Shimomura, Stephan Collins, Stephan Kaizik, Peter Proks, Fernando Abdulkader, Anne Clark, Vicky Ball, Lejla Zubcevic, Liz Bentley, Rebecca Clark, Chris Church, Alison Hugill, Juris Galvanovskis, Roger Cox, Patrik Rorsman, Jens C. Brüning, and Frances M. Ashcroft PMCID: PMC2613450 A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining
Mirjam van der Burg, Hanna IJspeert, Nicole S. Verkaik, Tuba Turul, Wouter W. Wiegant, Keiko Morotomi-Yano, Pierre-Olivier Mari, Ilhan Tezcan, David J. Chen, Malgorzata Z. Zdzienicka, Jacques J.M. van Dongen, and Dik C. van Gent PMCID: PMC2613452 Genetic and hormonal factors modulate spreading depression and transient
hemiparesis in mouse models of familial hemiplegic migraine type 1 Katharina Eikermann-Haerter, Ergin Dileköz, Chiho Kudo, Sean I. Savitz, Christian Waeber, Michael J. Baum, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Michael A. Moskowitz, and Cenk Ayata PMCID: PMC2613474 PPARγ in the endothelium regulates metabolic responses to high-fat diet in mice Takeshi Kanda, Jonathan D. Brown, Gabriela Orasanu, Silke Vogel, Frank J. Gonzalez, Juliano Sartoretto, Thomas Michel, and Jorge Plutzky PMCID: PMC2613459 Deletion of the von Hippel–Lindau gene in pancreatic
β cells impairs glucose homeostasis in mice James Cantley, Colin Selman, Deepa Shukla, Andrey Y. Abramov, Frauke Forstreuter, Miguel A. Esteban, Marc Claret, Steven J. Lingard, Melanie Clements, Sarah K. Harten, Henry Asare-Anane, Rachel L. Batterham, Pedro L. Herrera, Shanta J. Persaud, Michael R. Duchen, Patrick H. Maxwell, and Dominic J. Withers PMCID: PMC2613475 CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima Young Mi Park, Maria Febbraio, and Roy L. Silverstein PMCID: PMC2613464 Mutant Hoxd13 induces extra digits in a mouse model of synpolydactyly directly and by decreasing retinoic acid synthesis Pia Kuss, Pablo Villavicencio-Lorini, Florian Witte, Joachim Klose, Andrea N. Albrecht, Petra Seemann, Jochen Hecht, and Stefan Mundlos PMCID: PMC2613457 Harnessing endogenous miR-181a to segregate transgenic antigen receptor expression in developing versus post-thymic T cells in murine hematopoietic chimeras Eirini P. Papapetrou, Damian Kovalovsky, Laurent Beloeil, Derek Sant’Angelo, and Michel Sadelain PMCID: PMC2613472 Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis Jin Nakahara, Kohsuke Kanekura, Mikiro Nawa, Sadakazu Aiso, and Norihiro Suzuki PMCID: PMC2613458 Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
Vanessa Brochard, Béhazine Combadière, Annick Prigent, Yasmina Laouar, Aline Perrin, Virginie Beray-Berthat, Olivia Bonduelle, Daniel Alvarez-Fischer, Jacques Callebert, Jean-Marie Launay, Charles Duyckaerts, Richard A. Flavell, Etienne C. Hirsch, and Stéphane Hunot PMCID: PMC2613467 IRBIT coordinates epithelial fluid and HCO3– secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct
Dongki Yang, Nikolay Shcheynikov, Weizhong Zeng, Ehud Ohana, Insuk So, Hideaki Ando, Akihiro Mizutani, Katsuhiko Mikoshiba, and Shmuel Muallem PMCID: PMC2613461 Endoplasmic reticulum–mitochondria crosstalk in NIX-mediated murine cell death Abhinav Diwan, Scot J. Matkovich, Qunying Yuan, Wen Zhao, Atsuko Yatani, Joan Heller Brown, Jeffery D. Molkentin, Evangelia G. Kranias, and Gerald W. Dorn, II PMCID: PMC2613462 Epithelial cell α3β1 integrin links β-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis Kevin K. Kim, Ying Wei, Charles Szekeres, Matthias C. Kugler, Paul J. Wolters, Marla L. Hill, James A. Frank, Alexis N. Brumwell, Sarah E. Wheeler, Jordan A. Kreidberg, and Harold A. Chapman PMCID: PMC2613463 Technical Advance Genome-wide hepatitis C virus amino acid covariance networks can predict response to antiviral therapy in humans Rajeev Aurora, Maureen J. Donlin, Nathan A. Cannon, John E. Tavis, and the Virahep-C Study Group PMCID: PMC2613460 |
