NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

21 Protocols (16 Active Accrual of new subjects, 5 Follow-up of previously enrolled subjects)


Active Accrual, Protocols Recruiting New Patients 
* 09-AR-0006:
A Multi-Center, Open Label, 6-Month Treatment Study to Establish the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of Canakinumab (anti-IL-1 Beta Antibody) in Patients with NOMID / CINCA Syndrome

* 08-AR-0218:
Phase II Trial of Rilonacept for Treatment of Familial Mediterranean Fever (FMF)

* 08-AR-0029:
Phase Ib, MultiCenter Randomized, Double-Blind Placebo-Controlled, Dose Escalation Study w/Open-Label Extension to Evaluate Safety and Tolerability of Multiple IV Doses of MEDI-545; A Fully Human Anti-IFN-alpha Monoclonal Antibody in Patients w/SLE

* 05-AR-0014:
Continuation of a Pilot Open-Label Study of IL 1 Trap in Adult Subjects with Autoinflammatory Disease: A Therapeutic Approach to Study Pathogenesis

* 04-AR-0205:
Progression of Spinal Fusion in Ankylosing Spondylitis

* 03-AR-0298:
A Pilot Study with the IL-1 Receptor Antagonist Anakinra or Kineret in Patients with Neonatal Onset Multisystem Inflammatory Disease (NOMID/CINCA Syndrome)

* 03-AR-0173:
Studies of the Natural History and Pathogenesis of Neonatal Onset Multisystem Inflammatory Disease (NOMID)

* 03-AR-0133:
Clinically Important Changes in Rheumatoid Arthritis

* 03-AR-0131:
Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

* 02-AR-0131:
Collection Of Blood Components Using Apheresis From Patients With Rheumatic Diseases And Healthy Volunteers

* 01-AR-0227:
Natural History of Rheumatic Disease in Minority Communities

* 00-AR-0222:
Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions

* 99-AR-0004:
Molecular Basis of Primary Immunodeficiencies

* 94-AR-0105:
Genetics and Pathophysiology of Familial Mediterranean Fever and Related Disorders

* 94-AR-0066:
Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)

* 91-AR-0196:
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases

Active Follow-up, Protocols NOT Recruiting New Patients 

* 08-AR-0008:
Insulin Resistance and Atherosclerosis in a Sample of Women with Systemic Lupus Erythematosus

* 03-AR-0130:
Genetic Determinants of Ankylosing Spondylitis Severity - Cross Sectional Study

* 02-AR-0272:
A Phase I, Open-Labeled, Dose-Ascending Clinical Trial of Immunotherapy of MRA, A Humanized Anti-IL 6 Receptor Monoclonal Antibody, In Patients with Systemic Lupus Erythematosus

* 02-AR-0156:
A Randomized, Double-Blind, Placebo-Controlled Trial of Infliximab In Patients With Dermatomyositis and Polymyositis

* 98-AR-0124:
Genetics of Rheumatoid Arthritis: The North American Rheumatoid Arthritis Consortium

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