The Maternal Opioid Treatment: Human Experimental Research (MOTHER) Project is an international multi-site clinical trial comprised of eight research grants—six in the United States and one each in Canada and Austria—to evaluate the efficacy of buprenorphine as a pharmacotherapy for pregnant opioid dependent women. Multiple sites provide the necessary number of patients to test this new therapy.
Mission: To assess in opioid-dependent pregnant women the efficacy of buprenorphine for improving birth outcomes and reducing neonatal abstinence syndrome (NAS) relative to methadone
Obtain abstracts of grants and contact information.
Locations:
Maternal Opioid Treatment: Human Experimental Research Johns Hopkins University Dept. of Psychiatry & Behavioral Sciences 4940 Eastern Avenue, D-3 East Baltimore, MD 21224 Hendree Jones, Ph.D.
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Coordinating Center University of Maryland Center for Substance Research (CESAR) 4321 Hartwick Road, Suite 501 College Park, MD 20740 Amelia Arria, Ph.D.
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| | Maternal Opioid Treatment: Human Experimental Research Medical University of Vienna Dept. of Psychiatry Wahringer Gurtel 18-20 1090 Vienna Vienna, Austria Gabriele Fischer, M.D.
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| Maternal Opioid Treatment: Human Experimental Research University of Vermont Substance Abuse Treatment Center 1 South Prospect Street, Room 1415 Burlington, VT 05401 Sarah H. Heil, Ph.D.
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| | Maternal Opioid Treatment: Human Experimental Research Thomas Jefferson University Dept. of Pediatrics 1201 Chestnut Street, 9th Floor Philadelphia, PA 19107 Karol Kaltenbach, Ph.D.
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| Maternal Opioid Treatment: Human Experimental Research The Psychiatric Hospital at Vanderbilt 1601 23rd Avenue S., Suite 3068 Nashville, TN 37232 Peter R. Martin, M.D.
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| | Maternal Opioid Treatment: Human Experimental Research Wayne State University Dept. of Psychiatry & Behavioral Neurosciences 2761 E. Jefferson Detroit, MI 48207 Susan M. Stine, M.D., Ph.D.
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| Maternal Opioid Treatment: Human Experimental Research Brown University Dept. of Pediatrics 79 Plain Street, 2nd Floor Providence, RI 02903 Barry M. Lester, Ph.D.
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| | Maternal Opioid Treatment: Human
Experimental Research
St. Joseph's Health Centre
Dept. of Family Medicine 30 The Queensway Toronto, ON M6R 1B5 Canada Peter Selby, M.D.
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