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Volume 94(1);  January 2009
Editorials and Perspectives
Prognostic implications of anemia in older adults
Kushang V. Patel and Jack M. Guralnik
Haematologica. 2009 January; 94(1): 1–2. doi: 10.3324/haematol.2008.001289.
PMCID: PMC2625415
Paroxysmal nocturnal hemoglobinuria and myelodysplastic sydromes: clonal expansion of PIG-A-mutant hematopoietic cells in bone marrow failure
Neal S. Young
Haematologica. 2009 January; 94(1): 3–7. doi: 10.3324/haematol.2008.001297.
PMCID: PMC2625409
Clinical relevance of JAK2 (V617F) mutant allele burden
Francesco Passamonti and Elisa Rumi
Haematologica. 2009 January; 94(1): 7–10. doi: 10.3324/haematol.2008.001271.
PMCID: PMC2625431
Treatment of acute myeloid leukemia
Elihu H. Estey
Haematologica. 2009 January; 94(1): 10–16. doi: 10.3324/haematol.2008.001263.
PMCID: PMC2625419
Clinicobiological, prognostic and therapeutic implications of the tumor microenvironment in follicular lymphoma
Marylène Lejeune and Tomás Álvaro
Haematologica. 2009 January; 94(1): 16–21. doi: 10.3324/haematol.2008.001255.
PMCID: PMC2625413
Original Articles
Red Cell Disorders
Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study
Emma Riva, Mauro Tettamanti, Paola Mosconi, Giovanni Apolone, Francesca Gandini, Alessandro Nobili, Maria Vittoria Tallone, Paolo Detoma, Adriano Giacomin, Mario Clerico, Patrizia Tempia, Adriano Guala, Gilberto Fasolo, and Ugo Lucca
Haematologica. 2009 January; 94(1): 22–28. Published online 2008 November 10. doi: 10.3324/haematol.13449.
PMCID: PMC2625429
Myelodysplastic Syndromes
Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats
Sa A. Wang, Olga Pozdnyakova, Jeffrey L. Jorgensen, L. Jeffrey Medeiros, Dariusz Stachurski, Mary Anderson, Azra Raza, and Bruce A. Woda
Haematologica. 2009 January; 94(1): 29–37. Published online 2008 November 10. doi: 10.3324/haematol.13601.
PMCID: PMC2625410
Myeloproliferative Disorders
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study
Eric Lippert, François Girodon, Emma Hammond, Jaroslav Jelinek, N. Scott Reading, Boris Fehse, Katy Hanlon, Mirjam Hermans, Céline Richard, Sabina Swierczek, Valérie Ugo, Serge Carillo, Véronique Harrivel, Christophe Marzac, Daniela Pietra, Marta Sobas, Morgane Mounier, Marina Migeon, Sian Ellard, Nicolaus Kröger, Richard Herrmann, Josef T. Prchal, Radek C. Skoda, and Sylvie Hermouet
Haematologica. 2009 January; 94(1): 38–45. Published online 2008 November 10. doi: 10.3324/haematol.13486.
PMCID: PMC2625411
Acute Myeloid Leukemia
Correlation of minimal residual disease cell frequency with molecular genotype in patients with acute myeloid leukemia
Corine J. Hess, Nicole Feller, Fedor Denkers, Angèle Kelder, Pauline A. Merle, Michael C. Heinrich, Amy Harlow, Johannes Berkhof, Gert J. Ossenkoppele, Quinten Waisfisz, and Gerrit J. Schuurhuis
Haematologica. 2009 January; 94(1): 46–53. Published online 2008 November 27. doi: 10.3324/haematol.13110.
PMCID: PMC2625416
Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B
Richard F. Schlenk, Konstanze Döhner, Michael Kneba, Katharina Götze, Frank Hartmann, Francesco del Valle, Heinz Kirchen, Elisabeth Koller, Jörg T. Fischer, Lars Bullinger, Marianne Habdank, Daniela Späth, Silja Groner, Bernhard Krebs, Sabine Kayser, Andrea Corbacioglu, Andreas Anhalt, Axel Benner, Stefan Fröhling, and Hartmut Döhner
Haematologica. 2009 January; 94(1): 54–60. Published online 2008 December 4. doi: 10.3324/haematol.13378.
PMCID: PMC2625424
Malignant Lymphomas
The potential of copy number gains and losses, detected by array-based comparative genomic hybridization, for computational differential diagnosis of B-cell lymphomas and genetic regions involved in lymphomagenesis
Ichiro Takeuchi, Hiroyuki Tagawa, Akira Tsujikawa, Masao Nakagawa, Miyuki Katayama-Suguro, Ying Guo, and Masao Seto
Haematologica. 2009 January; 94(1): 61–69. Published online 2008 November 23. doi: 10.3324/haematol.12986.
PMCID: PMC2625430
Impact of the tumor microenvironment on prognosis in follicular lymphoma is dependent on specific treatment protocols
Daphne de Jong, Ad Koster, Anton Hagenbeek, John Raemaekers, Dennis Veldhuizen, Sabien Heisterkamp, Jan Paul de Boer, and Martine van Glabbeke
Haematologica. 2009 January; 94(1): 70–77. Published online 2008 December 4. doi: 10.3324/haematol.13574.
PMCID: PMC2625428
Multiple Myeloma
MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells
Jose L.R. Brito, Brian Walker, Matthew Jenner, Nicholas J. Dickens, Nicola J.M. Brown, Fiona M. Ross, Athanasia Avramidou, Julie A.E. Irving, David Gonzalez, Faith E. Davies, and Gareth J. Morgan
Haematologica. 2009 January; 94(1): 78–86. Published online 2008 December 4. doi: 10.3324/haematol.13426.
PMCID: PMC2625417
Impact of XIAP protein levels on the survival of myeloma cells
Grégoire Desplanques, Nicola Giuliani, Roberto Delsignore, Vittorio Rizzoli, Régis Bataille, and Sophie Barillé-Nion
Haematologica. 2009 January; 94(1): 87–93. Published online 2008 November 10. doi: 10.3324/haematol.13483.
PMCID: PMC2625405
Stem Cell Transplantation
Severe events in donors after allogeneic hematopoietic stem cell donation
Joerg Halter, Yoshihisa Kodera, Alvaro Urbano Ispizua, Hildegard T. Greinix, Norbert Schmitz, Geneviève Favre, Helen Baldomero, Dietger Niederwieser, Jane F. Apperley, and Alois Gratwohl
Haematologica. 2009 January; 94(1): 94–101. Published online 2008 December 4. doi: 10.3324/haematol.13668.
PMCID: PMC2625420
Decision Making and Problem Solving
Acute Myeloid Leukemia
Clinical management of primary non-acute promyelocytic leukemia acute myeloid leukemia: practice Guidelines by the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation
Enrica Morra, Giovanni Barosi, Alberto Bosi, Felicetto Ferrara, Franco Locatelli, Monia Marchetti, Giovanni Martinelli, Cristina Mecucci, Marco Vignetti, and Sante Tura
Haematologica. 2009 January; 94(1): 102–112. Published online 2008 November 10. doi: 10.3324/haematol.13166.
PMCID: PMC2625406
Fungal Infections
Primary prophylaxis of invasive fungal infections in patients with hematologic malignancies. Recommendations of the Infectious Diseases Working Party of the German Society for Haematology and Oncology
Oliver A. Cornely, Angelika Böhme, Dieter Buchheidt, Hermann Einsele, Werner J. Heinz, Meinolf Karthaus, Stefan W. Krause, William Krüger, Georg Maschmeyer, Olaf Penack, Jörg Ritter, Markus Ruhnke, Michael Sandherr, Michal Sieniawski, Jörg-Janne Vehreschild, Hans-Heinrich Wolf, and Andrew J. Ullmann
Haematologica. 2009 January; 94(1): 113–122. Published online 2008 December 9. doi: 10.3324/haematol.11665.
PMCID: PMC2625427
Brief Reports
Sickle Cell Disease
Effect of transfusion therapy on cerebral vasculopathy in children with sickle-cell anemia
Brigitte Bader-Meunier, Suzanne Verlhac, Monique Elmaleh-Bergès, Ghislaine Ithier, Fatiha Sellami, Sonia Faid, Florence Missud, Rolande Ducrocq, Corinne Alberti, Isabelle Zaccaria, Andre Baruchel, and Malika Benkerrou
Haematologica. 2009 January; 94(1): 123–126. Published online 2008 December 4. doi: 10.3324/haematol.13610.
PMCID: PMC2625404
Myeloproliferative Disorders
CD146+ bone marrow osteoprogenitors increase in the advanced stages of primary myelofibrosis
Claudio Tripodo, Andrea Di Bernardo, Maria Paola Ternullo, Carla Guarnotta, Rossana Porcasi, Sabrina Ingrao, Umberto Gianelli, Emanuela Boveri, Emilio Iannitto, Giovanni Franco, and Ada Maria Florena
Haematologica. 2009 January; 94(1): 127–130. Published online 2008 November 23. doi: 10.3324/haematol.13598.
PMCID: PMC2625423
Acute Myeloid Leukemia
Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling
Roel G.W. Verhaak, Bas J. Wouters, Claudia A.J. Erpelinck, Saman Abbas, H. Berna Beverloo, Sanne Lugthart, Bob Löwenberg, Ruud Delwel, and Peter J.M. Valk
Haematologica. 2009 January; 94(1): 131–134. Published online 2008 October 6. doi: 10.3324/haematol.13299.
PMCID: PMC2625407
Lymphoproliferative Disorders
Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia
Dong Hwan Kim, Suzanne Kamel-Reid, Hong Chang, Robert Sutherland, Chul Won Jung, Hyeoung-Joon Kim, Je-Jung Lee, and Jeffrey H. Lipton
Haematologica. 2009 January; 94(1): 135–139. Published online 2008 December 9. doi: 10.3324/haematol.13151.
PMCID: PMC2625403
Letters to the Editor
Thalassemia Syndromes
T2* cardiovascular magnetic resonance in the management of thalassemia patients in Oman
Shahina Daar, Anil V. Pathare, Rajeev Jain, Shoaib Al Zadjali, and Dudley J. Pennell
Haematologica. 2009 January; 94(1): 140–141. Published online 2008 November 10. doi: 10.3324/haematol.13845.
PMCID: PMC2625422
Myeloproliferative Disorders
Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis
Susanne Schnittger, Ulrike Bacher, Claudia Haferlach, Dietrich Beelen, Peter Bojko, Dieter Bürkle, Robert Dengler, Andrea Distelrath, Michael Eckart, Robert Eckert, Stefan Fries, Jan Knoblich, Georg Köchling, Hans-Peter Laubenstein, Petro Petrides, Manfred Planker, Rudolf Pihusch, Rudolf Weide, Wolfgang Kern, and Torsten Haferlach
Haematologica. 2009 January; 94(1): 141–144. Published online 2008 November 23. doi: 10.3324/haematol.13224.
PMCID: PMC2625421
JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis
Paola Guglielmelli, Giovanni Barosi, Lisa Pieri, Elisabetta Antonioli, Alberto Bosi, and Alessandro M. Vannucchi
Haematologica. 2009 January; 94(1): 144–146. Published online 2008 November 27. doi: 10.3324/haematol.13721.
PMCID: PMC2625425
Malignant Lymphomas
High-dose therapy and autologous stem cell transplantation versus conventional therapy for patients with advanced Hodgkin’s lymphoma responding to front-line therapy: long-term results
Angelo Michele Carella, Monica Bellei, Pauline Brice, Christian Gisselbrecht, Giuseppe Visani, Philippe Colombat, Francesco Fabbiano, Amedea Donelli, Stefano Luminari, Pierre Feugier, Peter Browett, Hans Hagberg, and Massimo Federico
Haematologica. 2009 January; 94(1): 146–148. Published online 2008 November 10. doi: 10.3324/haematol.13484.
PMCID: PMC2625418
Clinical relevance of MDM2 SNP 309 and TP53 Arg72Pro in follicular lymphoma
David Wrench, Rachel Waters, Emanuela Carlotti, Sameena Iqbal, Janet Matthews, Marie Calaminici, John Gribben, T. Andrew Lister, and Jude Fitzgibbon
Haematologica. 2009 January; 94(1): 148–150. Published online 2008 November 23. doi: 10.3324/haematol.13533.
PMCID: PMC2625408
Chronic Lymphocytic Leukemia
Pharmacokinetics of alemtuzumab in combination with fludarabine in patients with relapsed or refractory B-cell chronic lymphocytic leukemia
Thomas Elter, Julia Kilp, Peter Borchmann, Holger Schulz, Michael Hallek, and Andreas Engert
Haematologica. 2009 January; 94(1): 150–152. Published online 2008 November 10. doi: 10.3324/haematol.13379.
PMCID: PMC2625426
Stem Cell Transplantation
Respiratory depression and somnolence in children receiving dimethylsulfoxide and morphine during hematopoietic stem cells transplantation
Désirée Caselli, Veronica Tintori, Andrea Messeri, Stefano Frenos, Franco Bambi, and Maurizio Aricò
Haematologica. 2009 January; 94(1): 152–153. Published online 2008 November 10. doi: 10.3324/haematol.13828.
PMCID: PMC2625412
Obituary
Ernest Beutler (1928–2008)
Bruce Beutler
Haematologica. 2009 January; 94(1): 154–156. doi: 10.3324/haematol.13863.
PMCID: PMC2625414
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