Proteomics in Diabetes

	April 24, 2003
8:30 am	Meeting Opening Salvatore Sechi, Director Proteomic Program
8:35	Welcome and Introduction Allen Spiegel, Director NIDDK
8:45	KEYNOTE LECTURE Dissecting the Nutrient-Response Signaling Network Using Chemical Genetics Stuart L. Schreiber, Harvard University BIO http://www-schreiber.chem.harvard.edu http://iccb.med.harvard.edu/ http://www.cgr.harvard.edu/
	Protein Profiling and Quantitation (35 minute presentations, ~5 minutes for questions)
9:30	Quantitative Proteomics: New Technologies and Applications Ruedi Aebersold, The Institute for Systems Biology BIO: http://www.systemsbiology.org/Default.aspx?pagename=ruediaebersold
10:10	Break (20 minutes)
10:30	Functional Proteomic Analysis of Signal Transduction and Disease Natalie Ahn, University of Colorado BIO: http://www.colorado.edu/chemistry/faculty/Ahn/
11:10	Proteomics Methods to Elucidate Diabetes Related Signaling Matthias Mann, University of Southern Denmark - Odense University BIO: http://www.pil.sdu.dk/matthias_mann.htm
11:50	New Technologies for Comprehensive, Quantitative and High Throughput Proteomics Richard D. Smith, Pacific Northwest National Laboratory (PNNL) BIO: http://emslbios.pnl.gov/bios/biosketch.nsf/All+Public+Documents/Smith,+Richard+D?Opendocument
12:10	Computational Tools for High Throughput Proteomics Andy Keller, The Institute for Systems Biology http://www.systemsbiology.org
12:30 pm	Lunch (on your own)
	Protein Profiling and Quantitation (35 minute presentations, ~5 minutes for questions)
1:30	Adipose Tissue-Insulin Receptor Knockout Unmasks Heterogeneity of Protein and Gene Expression Patterns Depending on the Adipocyte Size C. Ronald Kahn, Joslin Diabetes Center BIO: http://www.joslindiabetescenter.org/news/new_president.shtml
2:10	Application of the Serum Proteome in Metabolic Diseases Christian Rholff, Oxford GlycoSciences, UK BIO: http://www.ogs.com
2:50	On the Pathogenesis of Type 1 Diabetes, Proteomic Studies Jorn Nerup, Steno Diabetes Center, Gentofte, Denmark
3:30	Break (20 minutes)
3:50	Cells and Organelles in Diabetes: A Combined Genomic and Proteomic Approach Silvia Corvera, University of Massachusetts Medical School BIO: http://www.umassmed.edu/igp/faculty/corvera.cfm?start=Research&name=corvera
4:30	Presentation on Hupo Proteomics Initiatives Samir Hanash, University of Michigan http://hupo.org
4:50	Poster Viewing and Refreshments
5:50	Adjournment Page Top

	April 25, 2003
	Protein Interaction and Computational Modeling (35 minute presentations, ~5 minutes for questions)
8:30 am	Integrating “Omic” Information: A Bridge Between Genomics and Systems Biology Marc Vidal, Harvard Medical School BIO: http://vidal.dfci.harvard.edu/main_pages/homepage.html
9:10	Accelerating Disease Gene Discovery through Integrative Genomics Vamsi Mootha, Whitehead Institute / MIT BIO: http://www-genome.wi.mit.edu/mpg/people/vmootha.html
	Talks Selected From Posters (10 minute presentations, ~5 minutes for questions)
9:50	Insulin Resistance and O-GlcNAc Modification of Nucleocytoplasmic Proteins *Lance Wells,** Stephen A. Whelan, Keith Vosseller, and Gerald W. Hart Department of Biological Chemistry,Johns Hopkins School of Medicine, Baltimore,MD*
10:05	Proteomics on Secretory Proteins from Adipose Cells Xiaoli Chen¹, Sonja Hess², Lewis Pannell² and Samuel W. Cushman¹ ¹EDMNS/DB and ²Structural Mass Spectrometry Facility, NIDDK, NIH, Bethesda, MD
10:20	Protein Profiling of Nuclear Proteins Regulated by EDG-1, a High Affinity G-Protein Coupled Receptor for Sphingosine-1-phosphate Menq-Jer Lee, Sung-Suk Chae, Nicollas Ancellin, Timothy Hla, David Han Center for Vascular Biology/ Department of Physiology University of Connecticut Health Center, Farmington, CT
10:35	Break (25 minutes)
	Protein Interaction and Computational Modeling (Continued) (35 minute presentations, ~5 minutes for questions)
11:00	The Biomolecular Interaction Network Database Christopher Hogue, University of Toronto, Canada BIO: http://bioinfo.mshri.on.ca/index.html
11:40	New Proteins in Insulin Signaling and Action Gus Lienhard, Dartmouth Medical School BIO: http://www.dartmouth.edu/~biochem/lienhard/people.html#PI
12:30 pm	Lunch on your own
	Target Discovery and Protein Function (35 minute presentations, ~5 minutes for questions)
1:30	DNA as a Pharmaceutical: Large Scale Proteomic Identification of Targets in Autoimmune Disease Allows Tolerization by Novel DNA Constructs Larry Steinman, Stanford University School of Medicine BIO: http://www.stanford.edu/group/neurology/fac/steinman.html
2:10	Differential Proteomic Analysis in Animal Models of Type 2 Diabetes and Obesity-A Search for New Molecular Targets Mike Cawthorne, The University of Buckingham, UK BIO: http://www.buckingham.ac.uk/clore/
2:50	Global Analysis of Biochemical Activities Using Protein Chips Mike Snyder, Yale University BIO: http://www.yale.edu/snyder/
3:20	Meeting Adjourns

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