Chairs/Organizers
Saul Genuth
Case Western Reserve University
Gerald W. Hart
Johns Hopkins University
Salvatore Sechi
National Institute of Diabetes and Digestive and Kidney Diseases |
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Purpose:
High-throughput DNA sequencing has changed biomedical research. It is, however,
apparent that knowledge of the genome alone is not sufficient for a complete
understanding of complex diseases. This is partially due to complex
environmental factors that together with the genotype determine a specific
phenotype. A phenotype at the molecular level can be partially characterized for
its proteins, macromolecular complexes, and their regulation that often occurs
at the post-translational level. The application of high-throughput protein
characterization methodologies to human specimens is usually considered part of
clinical proteomics.
The main topic of this workshop is the application of proteomic technologies to
clinical studies relevant to diabetes and its complications. Particular emphasis
will be on projects aimed at the identification of novel protein markers of
diabetes and pre-diabetes, but more generally the application of proteomics to
clinical studies will be discussed through various presentations and discussion
sessions.
This workshop also will provide a venue to bring together investigators with
expertise in proteomics and clinical investigators interested in applying this
technology to problems related to diabetes and its complications.
Sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases
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