| | This journal provides immediate access to some articles. Editorial The past climate change heats up Steven M. Stanley PMCID: PMC34292 Commentaries Of bears, conservation genetics, and the value of time travel Svante Pääbo PMCID: PMC34293 Closing the ring: Links between SMC proteins and chromosome
partitioning, condensation, and supercoiling Victor F. Holmes and Nicholas R. Cozzarelli PMCID: PMC34294 More surprises in translation: Initiation without the
initiator tRNA Uttam L. RajBhandary PMCID: PMC34295 Computation with biomolecules Junghuei Chen and David Harlan Wood PMCID: PMC34296 Perspective Ice-core evidence of abrupt climate changes Richard B. Alley PMCID: PMC34297 Nonglacial rapid climate events: Past and future Jonathan Overpeck and Robert Webb PMCID: PMC34298 Was a change in thermohaline circulation responsible for the
Little Ice Age? Wallace S. Broecker PMCID: PMC34299 Detecting Holocene changes in thermohaline circulation L. D. Keigwin and E. A. Boyle PMCID: PMC34300 Abrupt climate change and thermohaline circulation: Mechanisms
and predictability Jochem Marotzke PMCID: PMC34301 As climate changes, so do glaciers Thomas V. Lowell PMCID: PMC34302 Climate change and the tropical Pacific: The sleeping
dragon wakes R. T. Pierrehumbert PMCID: PMC34303 Sensitivity and rapidity of vegetational response to abrupt
climate change Dorothy Peteet PMCID: PMC34304 Abrupt climate change in the computer: Is it real? Thomas F. Stocker and Olivier Marchal PMCID: PMC34305 Special Features The past climate change heats up Steven M. Stanley PMCID: PMC34292 Ice-core evidence of abrupt climate changes Richard B. Alley PMCID: PMC34297 Nonglacial rapid climate events: Past and future Jonathan Overpeck and Robert Webb PMCID: PMC34298 Was a change in thermohaline circulation responsible for the
Little Ice Age? Wallace S. Broecker PMCID: PMC34299 Detecting Holocene changes in thermohaline circulation L. D. Keigwin and E. A. Boyle PMCID: PMC34300 Abrupt climate change and thermohaline circulation: Mechanisms
and predictability Jochem Marotzke PMCID: PMC34301 As climate changes, so do glaciers Thomas V. Lowell PMCID: PMC34302 Climate change and the tropical Pacific: The sleeping
dragon wakes R. T. Pierrehumbert PMCID: PMC34303 Sensitivity and rapidity of vegetational response to abrupt
climate change Dorothy Peteet PMCID: PMC34304 Abrupt climate change in the computer: Is it real? Thomas F. Stocker and Olivier Marchal PMCID: PMC34305 Research Articles Two terrestrial records of rapid climatic change during the glacial–Holocene transition (14,000– 9,000 calendar years B.P.) from Europe Hilary H. Birks and Brigitta Ammann PMCID: PMC26443 Paleoproterozoic snowball Earth: Extreme climatic and geochemical global change and its biological consequences Joseph L. Kirschvink, Eric J. Gaidos, L. Elizabeth Bertani, Nicholas J. Beukes, Jens Gutzmer, Linda N. Maepa, and Rachel E. Steinberger PMCID: PMC26445 Twentieth century climate change: Evidence from small glaciers Mark B. Dyurgerov and Mark F. Meier PMCID: PMC26446 Can ozone depletion and global warming interact to produce rapid climate change? Dennis L. Hartmann, John M. Wallace, Varavut Limpasuvan, David W. J. Thompson, and James R. Holton PMCID: PMC26447 From the Cover:
Climate and infectious disease: Use of remote sensing for detection of Vibrio cholerae by indirect measurement Brad Lobitz, Louisa Beck, Anwar Huq, Byron Wood, George Fuchs, A. S. G. Faruque, and Rita Colwell PMCID: PMC26452 Climate change is affecting altitudinal migrants and hibernating species David W. Inouye, Billy Barr, Kenneth B. Armitage, and Brian D. Inouye PMCID: PMC26486 Physical Sciences Applied Mathematics Very intense pulse in the groundwater flow in fissurized-porous stratum G. I. Barenblatt, E. A. Ingerman, H. Shvets, and J. L. Vázquez PMCID: PMC26438 Applied Physical Sciences The elasticity and failure of fluid-filled cellular solids: Theory and experiment M. Warner, B. L. Thiel, and A. M. Donald PMCID: PMC26439 Chemistry Femtosecond observation of benzyne intermediates in a molecular beam: Bergman rearrangement in the isolated molecule Eric W.-G. Diau, Joseph Casanova, John D. Roberts, and Ahmed H. Zewail PMCID: PMC26440 Archimedean solids: Transition metal mediated rational self-assembly of supramolecular-truncated tetrahedra Stefan Leininger, Jun Fan, Marion Schmitz, and Peter J. Stang PMCID: PMC26441 Computer Sciences From the Cover:
Molecular computation: RNA solutions to chess problems Dirk Faulhammer, Anthony R. Cukras, Richard J. Lipton, and Laura F. Landweber PMCID: PMC26442 Engineering Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes Hiroshi Mitsuoka, Erik B. Kistler, and Geert W. Schmid-Schönbein PMCID: PMC26511 Geology Two terrestrial records of rapid climatic change during the glacial–Holocene transition (14,000– 9,000 calendar years B.P.) from Europe Hilary H. Birks and Brigitta Ammann PMCID: PMC26443 Atmospheric energy for subsurface life on Mars? Benjamin P. Weiss, Yuk L. Yung, and Kenneth H. Nealson PMCID: PMC26444 Paleoproterozoic snowball Earth: Extreme climatic and geochemical global change and its biological consequences Joseph L. Kirschvink, Eric J. Gaidos, L. Elizabeth Bertani, Nicholas J. Beukes, Jens Gutzmer, Linda N. Maepa, and Rachel E. Steinberger PMCID: PMC26445 Geophysics Twentieth century climate change: Evidence from small glaciers Mark B. Dyurgerov and Mark F. Meier PMCID: PMC26446 Can ozone depletion and global warming interact to produce rapid climate change? Dennis L. Hartmann, John M. Wallace, Varavut Limpasuvan, David W. J. Thompson, and James R. Holton PMCID: PMC26447 Mathematics Twist fields, the elliptic genus, and hidden symmetry Arthur Jaffe PMCID: PMC26448 Statistics The multivariate L1-median and associated data depth Yehuda Vardi and Cun-Hui Zhang PMCID: PMC26449 Biological Sciences Agricultural Sciences Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9 Qihong Huang, Quinn L. Deveraux, Susumu Maeda, Guy S. Salvesen, Henning R. Stennicke, Bruce D. Hammock, and John C. Reed PMCID: PMC26450 Applied Biological Sciences Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor Frank R. Stermitz, Peter Lorenz, Jeanne N. Tawara, Lauren A. Zenewicz, and Kim Lewis PMCID: PMC26451 From the Cover:
Climate and infectious disease: Use of remote sensing for detection of Vibrio cholerae by indirect measurement Brad Lobitz, Louisa Beck, Anwar Huq, Byron Wood, George Fuchs, A. S. G. Faruque, and Rita Colwell PMCID: PMC26452 Biochemistry From the Cover:
Molecular computation: RNA solutions to chess problems Dirk Faulhammer, Anthony R. Cukras, Richard J. Lipton, and Laura F. Landweber PMCID: PMC26442 The subcellular localization of acetyl-CoA carboxylase 2 Lutfi Abu-Elheiga, William R. Brinkley, Ling Zhong, Subrahmanyam S. Chirala, Gebretateos Woldegiorgis, and Salih J. Wakil PMCID: PMC26453 A structural basis for integrin activation by the cytoplasmic tail of the αIIb-subunit Olga Vinogradova, Tom Haas, Edward F. Plow, and Jun Qin PMCID: PMC26454 Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein Xinli Lin, Gerald Koelsch, Shili Wu, Debbie Downs, Azar Dashti, and Jordan Tang PMCID: PMC26455 Consequences of placing an intramolecular crosslink in myosin S1 Kunihiko Konno, Kathleen Ue, Mikhail Khoroshev, Hugo Martinez, Bruce Ray, and Manuel F. Morales PMCID: PMC26456 Three-dimensional modeling of and ligand docking to vitamin D receptor ligand binding domain Keiko Yamamoto, Hiroyuki Masuno, Mihwa Choi, Kinichi Nakashima, Tetsuya Taga, Hiroshi Ooizumi, Kazuhiko Umesono, Wanda Sicinska, Janeen VanHooke, Hector F. DeLuca, and Sachiko Yamada PMCID: PMC26457 Self-assembly of large, ordered lamellae from non-bilayer lipids and integral membrane proteins in vitro Ilian Simidjiev, Svetla Stoylova, Heinz Amenitsch, Tamás Jávorfi, László Mustárdy, Peter Laggner, Andreas Holzenburg, and Győző Garab PMCID: PMC26458 Folding and activity of circularly permuted forms of a polytopic membrane protein Rudolf Beutler, Francesco Ruggiero, and Bernhard Erni PMCID: PMC26459 A regulator of G protein signaling interaction surface linked to effector specificity Mathew E. Sowa, Wei He, Theodore G. Wensel, and Olivier Lichtarge PMCID: PMC26460 Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors Kristen L. Pierce, Stuart Maudsley, Yehia Daaka, Louis M. Luttrell, and Robert J. Lefkowitz PMCID: PMC26461 Positive and negative regulation of endogenous genes by designed transcription factors Roger R. Beerli, Birgit Dreier, and Carlos F. Barbas, III PMCID: PMC26462 Host factor Hfq of Escherichia coli stimulates elongation of poly(A) tails by poly(A) polymerase I Eliane Hajnsdorf and Philippe Régnier PMCID: PMC26463 Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry Kirk McMillan, Marc Adler, Douglas S. Auld, John J. Baldwin, Eric Blasko, Leslie J. Browne, Daniel Chelsky, David Davey, Ronald E. Dolle, Keith A. Eagen, Shawn Erickson, Richard I. Feldman, Charles B. Glaser, Cornell Mallari, Michael M. Morrissey, Michael H. J. Ohlmeyer, Gonghua Pan, John F. Parkinson, Gary B. Phillips, Mark A. Polokoff, Nolan H. Sigal, Ronald Vergona, Marc Whitlow, Tish A. Young, and James J. Devlin PMCID: PMC26464 From the Cover:
Methionine-independent initiation of translation in the capsid
protein of an insect RNA virus Jun Sasaki and Nobuhiko Nakashima PMCID: PMC26465 Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase Hyun Kim, Hangil Park, Lucy Montalvo, and William J. Lennarz PMCID: PMC26466 Coupling between protein folding and allostery in the GroE chaperonin system Ofer Yifrach and Amnon Horovitz PMCID: PMC26467 Transition-state structure as a unifying basis in protein-folding mechanisms: Contact order, chain topology, stability, and the extended nucleus mechanism Alan R. Fersht PMCID: PMC26468 A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase James P. J. Chong, Mariko K. Hayashi, Martha N. Simon, Rui-Ming Xu, and Bruce Stillman PMCID: PMC26469 A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity Stephen A. Chappell, Gerald M. Edelman, and Vincent P. Mauro PMCID: PMC26470 Biophysics The elasticity and failure of fluid-filled cellular solids: Theory and experiment M. Warner, B. L. Thiel, and A. M. Donald PMCID: PMC26439 Determination of the binding sites of the proton transfer
inhibitors Cd2+ and Zn2+ in bacterial
reaction centers H. L. Axelrod, E. C. Abresch, M. L. Paddock, M. Y. Okamura, and G. Feher PMCID: PMC26471 Identification of the proton pathway in bacterial reaction centers: Replacement of Asp-M17 and Asp-L210 with Asn reduces the proton transfer rate in the presence of Cd2+ M. L. Paddock, G. Feher, and M. Y. Okamura PMCID: PMC26472 Femtosecond resolution of ligand-heme interactions in the
high-affinity quinol oxidase bd: A di-heme active site? Marten H. Vos, Vitaliy B. Borisov, Ursula Liebl, Jean-Louis Martin, and Alexander A. Konstantinov PMCID: PMC26473 Cell Biology The Golgi-associated COPI-coated buds and vesicles contain β/γ-actin Ferran Valderrama, Ana Luna, Teresa Babià, José A. Martínez-Menárguez, José Ballesta, Holger Barth, Christine Chaponnier, Jaime Renau-Piqueras, and Gustavo Egea PMCID: PMC26474 RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism Ji Li, Ildiko Sarosi, Xiao-Qiang Yan, Sean Morony, Casey Capparelli, Hong-Lin Tan, Susan McCabe, Robin Elliott, Sheila Scully, Gwyneth Van, Stephen Kaufman, Shao-Chieh Juan, Yu Sun, John Tarpley, Laura Martin, Kathleen Christensen, James McCabe, Paul Kostenuik, Hailing Hsu, Frederick Fletcher, Colin R. Dunstan, David L. Lacey, and William J. Boyle PMCID: PMC26475 A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity Tal Raveh, Hanna Berissi, Miriam Eisenstein, Taly Spivak, and Adi Kimchi PMCID: PMC26476 Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases Xingming Deng, Peter Ruvolo, Boyd Carr, and W. Stratford May, Jr. PMCID: PMC26477 The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest Sa Wang, Min Guo, Honghai Ouyang, Xiaoling Li, Carlos Cordon-Cardo, Akihiro Kurimasa, David J. Chen, Zvi Fuks, C. Clifton Ling, and Gloria C. Li PMCID: PMC26478 Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins Sylvia Krobitsch and Susan Lindquist PMCID: PMC26479 Neuropeptide Y (NPY) potentiates phenylephrine-induced mitogen-activated protein kinase activation in primary cardiomyocytes via NPY Y5 receptors Corinne Pellieux, Thérèse Sauthier, Andrea Domenighetti, Donald J. Marsh, Richard D. Palmiter, Hans-R. Brunner, and Thierry Pedrazzini PMCID: PMC26480 Myeloblastin is a granulocyte colony-stimulating factor-responsive gene conferring factor-independent growth to hematopoietic cells Pierre G. Lutz, Christel Moog-Lutz, Edith Coumau-Gatbois, Ladan Kobari, Yolande Di Gioia, and Yvon E. Cayre PMCID: PMC26481 Developmental Biology neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas Gérard Gradwohl, Andrée Dierich, Marianne LeMeur, and François Guillemot PMCID: PMC26482 Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes Ralph J. DiLeone, Gregory A. Marcus, Michelle D. Johnson, and David M. Kingsley PMCID: PMC26483 Zic2 regulates the kinetics of neurulation Takeharu Nagai, Jun Aruga, Osamu Minowa, Takashi Sugimoto, Yoshiki Ohno, Tetsuo Noda, and Katsuhiko Mikoshiba PMCID: PMC26484 Endogenous expression of Müllerian inhibiting substance in early postnatal rat Sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites Koji Watanabe, Trent R. Clarke, Andrew H. Lane, Xinzhong Wang, and Patricia K. Donahoe PMCID: PMC26485 Ecology Climate change is affecting altitudinal migrants and hibernating species David W. Inouye, Billy Barr, Kenneth B. Armitage, and Brian D. Inouye PMCID: PMC26486 Chemical defense against predation in an insect egg Thomas Eisner, Maria Eisner, Carmen Rossini, Vikram K. Iyengar, Braden L. Roach, Eva Benedikt, and Jerrold Meinwald PMCID: PMC26487 Evolution INAUGURAL ARTICLE by a Recently Elected Academy Member: Biodiversity of Costa Rican salamanders:
Implications of high levels of genetic differentiation and
phylogeographic structure for species formation Mario García-París, David A. Good, Gabriela Parra-Olea, and David B. Wake PMCID: PMC26488 High relatedness and inbreeding at the origin of eusociality in gall-inducing thrips T. W. Chapman, B. J. Crespi, B. D. Kranz, and M. P. Schwarz PMCID: PMC26489 From the Cover:
Population genetics of Ice Age brown bears Jennifer A. Leonard, Robert K. Wayne, and Alan Cooper PMCID: PMC26490 Hox cluster genomics in the horn shark, Heterodontus francisci Chang-Bae Kim, Chris Amemiya, Wendy Bailey, Kazuhiko Kawasaki, Jason Mezey, Webb Miller, Shinsei Minoshima, Nobuyoshi Shimizu, Günter Wagner, and Frank Ruddle PMCID: PMC26491 Identification of hepatitis B virus indigenous to chimpanzees Xiaolei Hu, Harold S. Margolis, Robert H. Purcell, James Ebert, and Betty H. Robertson PMCID: PMC26492 Genetics In vitro cloning of complex mixtures of DNA on microbeads: Physical separation of differentially expressed cDNAs Sydney Brenner, Steven R. Williams, Eric H. Vermaas, Thorsten Storck, Keith Moon, Christie McCollum, Jen-I Mao, Shujun Luo, James J. Kirchner, Sam Eletr, Robert B. DuBridge, Timothy Burcham, and Glenn Albrecht PMCID: PMC26493 Suppression of chromosome segregation defects of Escherichia coli muk mutants by mutations in topoisomerase I James A. Sawitzke and Stuart Austin PMCID: PMC26494 Mitochondrial carbonic anhydrase CA VB: Differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles Gul N. Shah, David Hewett-Emmett, Jeffrey H. Grubb, Mary C. Migas, Robert E. Fleming, Abdul Waheed, and William S. Sly PMCID: PMC26495 Nonlinearity in genetic decoding: Homologous DNA replicase genes use alternatives of transcriptional slippage or translational frameshifting Bente Larsen, Norma M. Wills, Chad Nelson, John F. Atkins, and Raymond F. Gesteland PMCID: PMC26496 Immunology Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen Robert Weissert, Anna Lobell, Katrien L. de Graaf, Sana Yousif Eltayeb, Roland Andersson, Tomas Olsson, and Hans Wigzell PMCID: PMC26497 Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10) Sergei V. Kotenko, Simona Saccani, Lara S. Izotova, Olga V. Mirochnitchenko, and Sidney Pestka PMCID: PMC26498 Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes Liping Yu, David T. Robles, Norio Abiru, Paramjit Kaur, Marian Rewers, Katalin Kelemen, and George S. Eisenbarth PMCID: PMC26499 The dual functions of Fas ligand in the regulation of peripheral CD8+ and CD4+ T cells Ivy Suzuki and Pamela J. Fink PMCID: PMC26500 Role of Syk in B-cell development and antigen-receptor signaling Richard J. Cornall, Alex M. Cheng, Tony Pawson, and Christopher C. Goodnow PMCID: PMC26501 Hypothyroidism in transgenic mice expressing IFN-γ in the thyroid P. Caturegli, M. Hejazi, K. Suzuki, O. Dohan, N. Carrasco, L. D. Kohn, and N. R. Rose PMCID: PMC26502 Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcγ receptors I and II/III Francisco A. Bonilla, Ross M. Fujita, Vadim I. Pivniouk, Andrew C. Chan, and Raif S. Geha PMCID: PMC26503 Medical Sciences Polycystin 1 is required for the structural integrity of blood vessels Keetae Kim, Iain Drummond, Oxana Ibraghimov-Beskrovnaya, Katherine Klinger, and M. Amin Arnaout PMCID: PMC26504 Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate Takumi Era and Owen N. Witte PMCID: PMC26505 Cardiolipin is a normal component of human plasma lipoproteins Hiroshi Deguchi, José A. Fernández, Tilman M. Hackeng, Carole L. Banka, and John H. Griffin PMCID: PMC26506 Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells Bing-Hua Jiang, Jenny Z. Zheng, Masahiro Aoki, and Peter K. Vogt PMCID: PMC26507 Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy Arul M. Chinnaiyan, Uttara Prasad, Sunita Shankar, Daniel A. Hamstra, Murthy Shanaiah, Thomas L. Chenevert, Brian D. Ross, and Alnawaz Rehemtulla PMCID: PMC26508 Human AML1/MDS1/EVI1 fusion protein induces an acute myelogenous leukemia (AML) in mice: A model for human AML Grace M. Cuenco, Giuseppina Nucifora, and Ruibao Ren PMCID: PMC26509 Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: A parasite adhesion trait implicated in cerebral malaria Joseph D. Smith, Alister G. Craig, Neline Kriek, Diana Hudson-Taylor, Sue Kyes, Toby Fagen, Robert Pinches, Dror I. Baruch, Chris I. Newbold, and Louis H. Miller PMCID: PMC26510 Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes Hiroshi Mitsuoka, Erik B. Kistler, and Geert W. Schmid-Schönbein PMCID: PMC26511 Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis Naftali Kaminski, John D. Allard, Jean F. Pittet, Fengrong Zuo, Mark J. D. Griffiths, David Morris, Xiaozhu Huang, Dean Sheppard, and Renu A. Heller PMCID: PMC26512 Lipotoxic heart disease in obese rats: Implications for human obesity Yan-Ting Zhou, Paul Grayburn, Asad Karim, Michio Shimabukuro, Moritake Higa, Dany Baetens, Lelio Orci, and Roger H. Unger PMCID: PMC26513 Enzyme plus light therapy to repair DNA damage in ultraviolet-B-irradiated human skin Helger Stege, Len Roza, Arie A. Vink, Markus Grewe, Thomas Ruzicka, Susanne Grether-Beck, and Jean Krutmann PMCID: PMC26514 Chemical chaperones mediate increased secretion of mutant α1-antitrypsin (α1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in α1-AT deficiency Jon A. J. Burrows, Lauren K. Willis, and David H. Perlmutter PMCID: PMC26515 Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicity D. B. Axworthy, J. M. Reno, M. D. Hylarides, R. W. Mallett, L. J. Theodore, L. M. Gustavson, F.-M. Su, L. J. Hobson, P. L. Beaumier, and A. R. Fritzberg PMCID: PMC26516 From the Cover:
The epidemiology of antibiotic resistance in hospitals: Paradoxes and prescriptions Marc Lipsitch, Carl T. Bergstrom, and Bruce R. Levin PMCID: PMC26540 Microbiology Atmospheric energy for subsurface life on Mars? Benjamin P. Weiss, Yuk L. Yung, and Kenneth H. Nealson PMCID: PMC26444 Facilitated diffusion of fructose via the phosphoenolpyruvate/glucose phosphotransferase system of Escherichia coli Hans L. Kornberg, Linda T. M. Lambourne, and Andrew A. Sproul PMCID: PMC26517 Defensive extrusive ectosymbionts of Euplotidium (Ciliophora) that contain microtubule-like structures are bacteria related to Verrucomicrobia Giulio Petroni, Stefan Spring, Karl-Heinz Schleifer, Franco Verni, and Giovanna Rosati PMCID: PMC26518 A herpes simplex virus 1 recombinant lacking the glycoprotein G coding sequences is defective in entry through apical surfaces of polarized epithelial cells in culture and in vivo Lorren C. Tran, Jennifer M. Kissner, Larry E. Westerman, and Amy E. Sears PMCID: PMC26519 Neurobiology Importance of newly generated neurons in the adult olfactory bulb for odor discrimination Gilles Gheusi, Harold Cremer, Heather McLean, Geneviève Chazal, Jean-Didier Vincent, and Pierre-Marie Lledo PMCID: PMC26520 Activation of a heterologously expressed octopamine receptor coupled only to adenylyl cyclase produces all the features of presynaptic facilitation in Aplysia sensory neurons Deok-Jin Chang, Xiao-Ching Li, Yong-Seok Lee, Hyong-Kyu Kim, Ueon Suk Kim, Nam Jeong Cho, Xinmian Lo, Klaudiusz R. Weiss, Eric R. Kandel, and Bong-Kiun Kaang PMCID: PMC26521 An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins Seana O'Regan, Elisabeth Traiffort, Martial Ruat, Nathalie Cha, Désiré Compaoré, and François-Marie Meunier PMCID: PMC26522 Columnar distribution of serotonin-dependent plasticity within kitten striate cortex Ljubomir Kojic, Richard H. Dyck, Qiang Gu, Robert M. Douglas, Joanne Matsubara, and Max S. Cynader PMCID: PMC26523 Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate–nitric oxide neurotransmission Andrew A. Pieper, Seth Blackshaw, Emily E. Clements, Daniel J. Brat, David K. Krug, Alison J. White, Patricia Pinto-Garcia, Antonella Favit, Jill R. Conover, Solomon H. Snyder, and Ajay Verma PMCID: PMC26524 Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: Evidence from genomic deletion of biosynthetic enzymes L. Xue, G. Farrugia, S. M. Miller, C. D. Ferris, S. H. Snyder, and J. H. Szurszewski PMCID: PMC26525 Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors P. Svenningsson, M. Lindskog, C. Ledent, M. Parmentier, P. Greengard, B. B. Fredholm, and G. Fisone PMCID: PMC26526 Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells Elizabeth A. Vitalis, James L. Costantin, Pei-San Tsai, Hideya Sakakibara, Sreenivasan Paruthiyil, Taroh Iiri, Jean-Francois Martini, Michiyoshi Taga, Amy L. H. Choi, Andrew C. Charles, and Richard I. Weiner PMCID: PMC26527 Gamma rhythms and beta rhythms have different synchronization properties N. Kopell, G. B. Ermentrout, M. A. Whittington, and R. D. Traub PMCID: PMC26528 Circadian modulation of dopamine receptor responsiveness in Drosophila melanogaster Rozi Andretic and Jay Hirsh PMCID: PMC26529 Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice Brigitte Dumartin, Mohamed Jaber, Francois Gonon, Marc G. Caron, Bruno Giros, and Bertrand Bloch PMCID: PMC26530 Pharmacology Induction of topoisomerase I cleavage complexes by 1-β-d-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells Philippe Pourquier, Yuji Takebayashi, Yoshimasa Urasaki, Christopher Gioffre, Glenda Kohlhagen, and Yves Pommier PMCID: PMC26531 Physiology Ascorbic acid acts as an inhibitory transmitter in the hypothalamus to inhibit stimulated luteinizing hormone-releasing hormone release by scavenging nitric oxide Sharada Karanth, Wen H. Yu, Anna Walczewska, Claudio Mastronardi, and Samuel M. McCann PMCID: PMC26532 Plant Biology Isolation and characterization of powdery mildew-resistant Arabidopsis mutants John Vogel and Shauna Somerville PMCID: PMC26533 UV light selectively coinduces supply pathways from primary metabolism and flavonoid secondary product formation in parsley Elke Logemann, Annette Tavernaro, Wolfgang Schulz, Imre E. Somssich, and Klaus Hahlbrock PMCID: PMC26534 Alternatively spliced N resistance gene transcripts: Their possible role in tobacco mosaic virus resistance S. P. Dinesh-Kumar and Barbara J. Baker PMCID: PMC26535 The production of recombinant proteins in transgenic barley grains Henriette Horvath, Jintai Huang, Oi Wong, Elizabeth Kohl, Thomas Okita, C. Gamini Kannangara, and Diter von Wettstein PMCID: PMC26536 The pollen determinant of self-incompatibility in Brassica campestris Seiji Takayama, Hiroshi Shiba, Megumi Iwano, Hiroko Shimosato, Fang-Sik Che, Naoko Kai, Masao Watanabe, Go Suzuki, Kokichi Hinata, and Akira Isogai PMCID: PMC26537 A novel precursor recognition element facilitates posttranslational binding to the signal recognition particle in chloroplasts Justin DeLille, Eric C. Peterson, Tracey Johnson, Misty Moore, Alicia Kight, and Ralph Henry PMCID: PMC26538 Elemental propagation of calcium signals in response-specific patterns determined by environmental stimulus strength Helen Goddard, N. F. H. Manison, D. Tomos, and C. Brownlee PMCID: PMC26539 Population Biology From the Cover:
The epidemiology of antibiotic resistance in hospitals: Paradoxes and prescriptions Marc Lipsitch, Carl T. Bergstrom, and Bruce R. Levin PMCID: PMC26540 Psychology Parsing executive processes: Strategic vs. evaluative functions of the anterior cingulate cortex Cameron S. Carter, Angus M. Macdonald, Matthew Botvinick, Laura L. Ross, V. Andrew Stenger, Douglas Noll, and Jonathan D. Cohen PMCID: PMC26541 Correction Proc Natl Acad Sci U S A. 2000 February 15; 97(4): 1949. Published online 2000 February 4. PMCID: PMC55972 Corrects: Rafael Maldonado, et al. Altered emotional and locomotor responses in mice deficient in the transcription factor CREM. Proc Natl Acad Sci U S A. 1999 November 23; 96(24): 14094–14099. Retractions Proc Natl Acad Sci U S A. 2000 February 15; 97(4): 1949. PMCID: PMC55973 Retracts: J M Ritchie, et al. Sodium channels in the cytoplasm of Schwann cells. Proc Natl Acad Sci U S A. 1990 December; 87(23): 9290–9294. Proc Natl Acad Sci U S A. 2000 February 15; 97(4): 1949. PMCID: PMC55974 Retracts: J M Ritchie, et al. Sodium channels in the cytoplasm of Schwann cells. Proc Natl Acad Sci U S A. 1990 December; 87(23): 9290–9294. |
