| | This journal provides immediate access to some articles. Commentaries Hominids and hybrids: The place of Neanderthals in human evolution Ian Tattersall and Jeffrey H. Schwartz PMCID: PMC33580 The tangled biology of tau Kirk C. Wilhelmsen PMCID: PMC33581 Coming or going it’s another pretty picture for the λ-Int
family album Arthur Landy PMCID: PMC33582 Augmenting β receptors in the heart: Short-term gains offset by
long-term pains? Lee E. Limbird and Douglas E. Vaughan PMCID: PMC33583 Permanence of brain sex differences and structural plasticity of the
adult brain Bruce S. McEwen PMCID: PMC33584 Physical Sciences Chemistry A method for high-sensitivity peptide sequencing using postsource decay matrix-assisted laser desorption ionization mass spectrometry T. Keough, R. S. Youngquist, and M. P. Lacey PMCID: PMC22028 Passive entry of a DNA molecule into a small pore Pierre-Gilles de Gennes PMCID: PMC22072 Biological Sciences Biochemistry Purification of transcription cofactor complex CRSP Soojin Ryu and Robert Tjian PMCID: PMC22029 Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse Feng Guo, Deshmukh N. Gopaul, and Gregory D. Van Duyne PMCID: PMC22031 mRNA cap recognition: Dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains Guanghui Hu, Paul D. Gershon, Alec E. Hodel, and Florante A. Quiocho PMCID: PMC22034 Chromatin structure analysis of the mouse Xist locus Veronica McCabe, Emma J. Formstone, Laura P. O’Neill, Bryan M. Turner, and Neil Brockdorff PMCID: PMC22037 Glutamine synthetase inactivation by protein–protein interaction Mario García-Domínguez, José C. Reyes, and Francisco J. Florencio PMCID: PMC22038 Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl–CoA reductase Lydia Tabernero, Daniel A. Bochar, Victor W. Rodwell, and Cynthia V. Stauffacher PMCID: PMC22040 Identification of SH2-Bβ as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2 Liangyou Rui and Christin Carter-Su PMCID: PMC22043 Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells Simona Raffioni, Didier Thomas, Erik D. Foehr, Leslie M. Thompson, and Ralph A. Bradshaw PMCID: PMC22045 Heat-inactivated proteins are rescued by the DnaK ![[center dot]](corehtml/pmc/pmcents/middot.gif) J-GrpE set and ClpB chaperones Ken Motohashi, Yohei Watanabe, Masafumi Yohda, and Masasuke Yoshida PMCID: PMC22047 Bypassing the periplasm: Reconstitution of the AcrAB multidrug efflux pump of Escherichia coli Helen I. Zgurskaya and Hiroshi Nikaido PMCID: PMC22048 Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove Yuji Takebayashi, Philippe Pourquier, Akira Yoshida, Glenda Kohlhagen, and Yves Pommier PMCID: PMC22050 An inactive open complex mediated by an UP element at Escherichia coli promoters Hideaki Tagami and Hiroji Aiba PMCID: PMC22052 Host-cell positive transcription elongation factor b kinase activity is essential and limiting for HIV type 1 replication Osvaldo Flores, Gary Lee, Joseph Kessler, Michael Miller, William Schlief, Joanne Tomassini, and Daria Hazuda PMCID: PMC22054 NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun Cristina López-Rodríguez, José Aramburu, Andrew S. Rakeman, and Anjana Rao PMCID: PMC22056 Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target Per-Johan Jakobsson, Staffan Thorén, Ralf Morgenstern, and Bengt Samuelsson PMCID: PMC22058 Purification of the yeast U4/U6 U5 small nuclear ribonucleoprotein particle and identification of its proteins Scott W. Stevens and John Abelson PMCID: PMC22060 The α-helix folds on the millisecond time scale David T. Clarke, Andrew J. Doig, Benjamin J. Stapley, and Gareth R. Jones PMCID: PMC22062 cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain Erik G. Lund, Joseph M. Guileyardo, and David W. Russell PMCID: PMC22064 Biophysics Electrically driven motor in the outer hair cell: Effect of a mechanical constraint M. Adachi and K. H. Iwasa PMCID: PMC22066 The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule Himangshu S. Bose, Randy M. Whittal, Michael A. Baldwin, and Walter L. Miller PMCID: PMC22068 A single amino acid near the C terminus of the synaptosomeassociated protein of 25 kDa (SNAP-25) is essential for exocytosis in chromaffin cells Manuel Criado, Anabel Gil, Salvador Viniegra, and Luis M. Gutiérrez PMCID: PMC22070 Passive entry of a DNA molecule into a small pore Pierre-Gilles de Gennes PMCID: PMC22072 Cell Biology Hepatic differentiation induced by oncostatin M attenuates fetal liver hematopoiesis Taisei Kinoshita, Takashi Sekiguchi, Ming-jiang Xu, Yoshiaki Ito, Akihide Kamiya, Koh-ichiro Tsuji, Tatsutoshi Nakahata, and Atsushi Miyajima PMCID: PMC22074 Receptor recruitment: A mechanism for interactions between G protein-coupled receptors Ulla Holtbäck, Hjalmar Brismar, Gerald F. DiBona, Michael Fu, Paul Greengard, and Anita Aperia PMCID: PMC22075 Separation of C/EBPα-mediated proliferation arrest and differentiation pathways Christine Müller, Marianna Alunni-Fabbroni, Elisabeth Kowenz-Leutz, Xianming Mo, Massimo Tommasino, and Achim Leutz PMCID: PMC22076 A functional bone morphogenetic protein system in the ovary Shunichi Shimasaki, Rob J. Zachow, Danmei Li, Holly Kim, Shun-ichiro Iemura, Naoto Ueno, Kuber Sampath, R. Jeffrey Chang, and Gregory F. Erickson PMCID: PMC22077 Genetic dissection of the budding yeast Arp2/3 complex: A comparison of the in vivo and structural roles of individual subunits Dirk C. Winter, Elizabeth Y. Choe, and Rong Li PMCID: PMC22078 Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy Zhen Hou, Que Nguyen, Baruch Frenkel, Susan K. Nilsson, Moira Milne, André J. van Wijnen, Janet L. Stein, Peter Quesenberry, Jane B. Lian, and Gary S. Stein PMCID: PMC22079 Ezrin, a plasma membrane–microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway Alexis Gautreau, Patrick Poullet, Daniel Louvard, and Monique Arpin PMCID: PMC22080 Cdc20 associates with the kinase aurora2/Aik Dawn C. Farruggio, Fiona M. Townsley, and Joan V. Ruderman PMCID: PMC22081 The intracellular parasite Theileria parva protects infected T cells from apoptosis Volker T. Heussler, Joel Machado, Jr, Paula C. Fernandez, Catherine Botteron, Chao-Guang Chen, Martin J. Pearse, and Dirk A. E. Dobbelaere PMCID: PMC22082 Developmental Biology Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice Felix Beck, Kallayanee Chawengsaksophak, Paul Waring, Raymond J. Playford, and John B. Furness PMCID: PMC22083 Normal growth and development in the absence of hepatic insulin-like growth factor I Shoshana Yakar, Jun-Li Liu, Bethel Stannard, Andrew Butler, Domenici Accili, Brian Sauer, and Derek LeRoith PMCID: PMC22084 Branching morphogenesis independent of mesenchymal–epithelial contact in the developing kidney Jizeng Qiao, Hiroyuki Sakurai, and Sanjay K. Nigam PMCID: PMC22085 Selective activation of the versican promoter by epithelial– mesenchymal interactions during hair follicle development Jiro Kishimoto, Ritsuko Ehama, Lin Wu, Shuwei Jiang, Nanyan Jiang, and Robert E. Burgeson PMCID: PMC22086 Ecology Folkecology and commons management in the Maya Lowlands Scott Atran, Douglas Medin, Norbert Ross, Elizabeth Lynch, John Coley, Edilberto Ucan Ek’, and Valentina Vapnarsky PMCID: PMC22132 Evolution MADS-box genes reveal that gnetophytes are more closely related to conifers than to flowering plants Kai-Uwe Winter, Annette Becker, Thomas Münster, Jan T. Kim, Heinz Saedler, and Günter Theissen PMCID: PMC22087 Mutation, recombination, and incipient speciation of bacteria in the laboratory Marin Vulić, Richard E. Lenski, and Miroslav Radman PMCID: PMC22088 Widespread intra-serotype recombination in natural populations of dengue virus Michael Worobey, Andrew Rambaut, and Edward C. Holmes PMCID: PMC22089 Proposal for a standardized temporal scheme of biological classification for extant species John C. Avise and Glenn C. Johns PMCID: PMC22090 Genetics Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others Laura Carrel and Huntington F. Willard PMCID: PMC22091 Conditional requirement for the Flk-1 receptor in the in vitro generation of early hematopoietic cells Michihiro Hidaka, William L. Stanford, and Alan Bernstein PMCID: PMC22092 Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation Guangbin Luo, Michelle S. Yao, Carla F. Bender, Michael Mills, Anthony R. Bladl, Allan Bradley, and John H. J. Petrini PMCID: PMC22093 Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array Steven A. Ahrendt, Sarel Halachmi, John T. Chow, Li Wu, Naomi Halachmi, Stephen C. Yang, Scott Wehage, Jin Jen, and David Sidransky PMCID: PMC22094 Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington’s disease brain nuclei Marcela V. Karpuj, Hideki Garren, Hilda Slunt, Donald L. Price, James Gusella, Mark W. Becher, and Lawrence Steinman PMCID: PMC22095 Neurosecretory control of aging in Caenorhabditis elegans Michael Ailion, Takao Inoue, Carole I. Weaver, Robert W. Holdcraft, and James H. Thomas PMCID: PMC22096 Stimulation of homologous recombination in plants by expression of the bacterial resolvase RuvC Gil Shalev, Yaron Sitrit, Naomi Avivi-Ragolski, Conrad Lichtenstein, and Avraham A. Levy PMCID: PMC22097 The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system Naomichi Matsukawa, Wojciech J. Grzesik, Nobuyuki Takahashi, Kailash N. Pandey, Stephen Pang, Mitsuo Yamauchi, and Oliver Smithies PMCID: PMC22098 Colinearity and its exceptions in orthologous adh regions of maize and sorghum Alexander P. Tikhonov, Phillip J. SanMiguel, Yuko Nakajima, Nina M. Gorenstein, Jeffrey L. Bennetzen, and Zoya Avramova PMCID: PMC22099 Efficient export of the glucose transporter Hxt1p from the endoplasmic reticulum requires Gsf2p Peter W. Sherwood and Marian Carlson PMCID: PMC22100 Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 William H. Biggs, III, Jill Meisenhelder, Tony Hunter, Webster K. Cavenee, and Karen C. Arden PMCID: PMC22101 The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway Valia T. Mihaylova, Christina Z. Borland, Laura Manjarrez, Michael J. Stern, and Hong Sun PMCID: PMC22102 An engineered closterovirus RNA replicon and analysis of heterologous terminal sequences for replication T. Satyanarayana, S. Gowda, V. P. Boyko, M. R. Albiach-Marti, M. Mawassi, J. Navas-Castillo, A. V. Karasev, V. Dolja, M. E. Hilf, D. J. Lewandowski, P. Moreno, M. Bar-Joseph, S. M. Garnsey, and W. O. Dawson PMCID: PMC22103 Immunology Induction of differentiation of pre-NKT cells to mature Vα14
NKT cells by granulocyte/macrophage colony-stimulating factor Hiroshi Sato, Toshinori Nakayama, Yujiro Tanaka, Masakatsu Yamashita, Yoichi Shibata, Eisuke Kondo, Yasushi Saito, and Masaru Taniguchi PMCID: PMC22104 Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes O. Rötzschke, K. Falk, J. Mack, J. M. Lau, G. Jung, and J. L. Strominger PMCID: PMC22105 Cytolytic and IFN-γ-producing activities of γδ T cells in the mouse intestinal epithelium are T cell receptor-β-chain dependent Masako Kohyama, Masanobu Nanno, Mariko Kawaguchi-Miyashita, Shinichiro Shimada, Mamoru Watanabe, Toshifumi Hibi, Schuichi Kaminogawa, and Hiromichi Ishikawa PMCID: PMC22106 Medical Sciences Cancer-specific chromosome alterations in the constitutive fragile region FRA3B Koshi Mimori, Teresa Druck, Hiroshi Inoue, Hansjuerg Alder, Lori Berk, Masaki Mori, Kay Huebner, and Carlo M. Croce PMCID: PMC22107 Treatment of noninfectious intermediate and posterior uveitis
with the humanized anti-Tac mAb: A phase I/II clinical trial Robert B. Nussenblatt, Eric Fortin, Rhett Schiffman, Luiz Rizzo, Janine Smith, Paul Van Veldhuisen, Pushpa Sran, Anita Yaffe, Carolyn K. Goldman, Thomas A. Waldmann, and Scott M. Whitcup PMCID: PMC22108 Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9 Subhra Ranjan Chakrabarti, Rashmi Sood, Surajit Ganguly, Stefan Bohlander, Zhiyuan Shen, and Giuseppina Nucifora PMCID: PMC22109 A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders Teresa C. Leone, Carla J. Weinheimer, and Daniel P. Kelly PMCID: PMC22110 X inactivation and somatic cell selection rescue female mice carrying a Piga-null mutation Peter Keller, Gabi Tremml, Vittorio Rosti, and Monica Bessler PMCID: PMC22111 JC virus DNA is present in the mucosa of the human colon and in colorectal cancers Luigi Laghi, Ann E. Randolph, D. P. Chauhan, Giancarlo Marra, Eugene O. Major, James V. Neel, and C. Richard Boland PMCID: PMC22112 Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention Xiaolin Zi and Rajesh Agarwal PMCID: PMC22113 Microbiology Constitutive cell surface association between CD4 and CCR5 Xiaodong Xiao, Lijun Wu, Tzanko S. Stantchev, Yan-Ru Feng, Sophie Ugolini, Hong Chen, Zhimin Shen, James L. Riley, Christopher C. Broder, Quentin J. Sattentau, and Dimiter S. Dimitrov PMCID: PMC22114 Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases Ferric C. Fang, Mary Ann DeGroote, John W. Foster, Andreas J. Bäumler, Urs Ochsner, Traci Testerman, Shawn Bearson, Jean-Christophe Giárd, Yisheng Xu, Gail Campbell, and Tracey Laessig PMCID: PMC22115 Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8+ T lymphocytes S. Mazher Husain, Edward J. Usherwood, Heather Dyson, Christopher Coleclough, Michael A. Coppola, David L. Woodland, Marcia A. Blackman, James P. Stewart, and Jeffery T. Sample PMCID: PMC22116 Neurobiology The neural substrate and temporal dynamics of interference effects in working memory as revealed by event-related functional MRI Mark D’Esposito, Bradley R. Postle, John Jonides, and Edward E. Smith PMCID: PMC22117 Relationship between presynaptic calcium transients and postsynaptic currents at single γ-aminobutyric acid (GABA)ergic boutons S. Kirischuk, N. Veselovsky, and R. Grantyn PMCID: PMC22118 Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis Daniel A. Lim and Arturo Alvarez-Buylla PMCID: PMC22119 Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects Kazim A. Sheikh, Ji Sun, Yujing Liu, Hiromichi Kawai, Thomas O. Crawford, Richard L. Proia, John W. Griffin, and Ronald L. Schnaar PMCID: PMC22120 A brain sexual dimorphism controlled by adult circulating androgens Bradley M. Cooke, Golnaz Tabibnia, and S. Marc Breedlove PMCID: PMC22121 Gap-junctional coupling between neurons and astrocytes in primary central nervous system cultures Maira M. Fróes, Ana Helena P. Correia, José Garcia-Abreu, David C. Spray, Antônio C. Campos de Carvalho, and Vivaldo Moura Neto PMCID: PMC22122 Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis Xiao Xu, Daseng Yang, Tony Wyss-Coray, Jim Yan, Li Gan, Yi Sun, and Lennart Mucke PMCID: PMC22123 Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3 Martin Biel, Mathias Seeliger, Alexander Pfeifer, Konrad Kohler, Andrea Gerstner, Andreas Ludwig, Gesine Jaissle, Sascha Fauser, Eberhart Zrenner, and Franz Hofmann PMCID: PMC22124 Somatotopy of the lateral line projection in larval zebrafish Daniel Alexandre and Alain Ghysen PMCID: PMC22125 Pharmacology Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis Timothy D. Warner, Francesco Giuliano, Ivana Vojnovic, Antoaneta Bukasa, Jane A. Mitchell, and John R. Vane PMCID: PMC22126 Activation of erythropoietin receptor in the absence of hormone by a peptide that binds to a domain different from the hormone binding site Tatjana Naranda, Kenneth Wong, R. Ilene Kaufman, Avram Goldstein, and Lennart Olsson PMCID: PMC22127 Plant Biology Suppression of the heterotrimeric G protein causes abnormal morphology, including dwarfism, in rice Yukiko Fujisawa, Teruhisa Kato, Shizuka Ohki, Atsushi Ishikawa, Hidemi Kitano, Takuji Sasaki, Tadashi Asahi, and Yukimoto Iwasaki PMCID: PMC22128 AKT3, a phloem-localized K+ channel, is blocked by protons I. Marten, S. Hoth, R. Deeken, P. Ache, K. A. Ketchum, T. Hoshi, and R. Hedrich PMCID: PMC22129 Psychology Distribution of tactile learning and its neural basis Justin A. Harris, Rasmus S. Petersen, and Mathew E. Diamond PMCID: PMC22130 Impairments in verb morphology after brain injury: A connectionist model Marc F. Joanisse and Mark S. Seidenberg PMCID: PMC22131 Social Sciences Anthropology Folkecology and commons management in the Maya Lowlands Scott Atran, Douglas Medin, Norbert Ross, Elizabeth Lynch, John Coley, Edilberto Ucan Ek’, and Valentina Vapnarsky PMCID: PMC22132 The early Upper Paleolithic human skeleton from the Abrigo do Lagar Velho (Portugal) and modern human emergence in Iberia Cidália Duarte, João Maurício, Paul B. Pettitt, Pedro Souto, Erik Trinkaus, Hans van der Plicht, and João Zilhão PMCID: PMC22133 Corrections Proc Natl Acad Sci U S A. 1999 June 22; 96(13): 7610. PMCID: PMC56103 Corrects: Ingrid Remy, et al. Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays. Proc Natl Acad Sci U S A. 1999 May 11; 96(10): 5394–5399. Proc Natl Acad Sci U S A. 1999 June 22; 96(13): 7610. PMCID: PMC56104 Corrects: I. Apostolou, et al. Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls. Proc Natl Acad Sci U S A. 1999 April 27; 96(9): 5141–5146. Proc Natl Acad Sci U S A. 1999 June 22; 96(13): 7610. PMCID: PMC56105 Corrects: R. Beau Lotto, et al. Mach bands as empirically derived associations. Proc Natl Acad Sci U S A. 1999 April 27; 96(9): 5245–5250. Proc Natl Acad Sci U S A. 1999 June 22; 96(13): 7610. PMCID: PMC56106 Corrects: Sunil P. Gandhi, et al. Spatial attention affects brain activity in human primary visual cortex. Proc Natl Acad Sci U S A. 1999 March 16; 96(6): 3314–3319. |
