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Volume 1(1);  October 2003
Message from the Founders
Why PLoS Became a Publisher
Patrick O Brown, Michael B Eisen, and Harold E Varmus
PLoS Biol. 2003 October; 1(1): e36. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000036.
PMCID: PMC212706
Editorial
PLoS Biology—We're Open
Philip Bernstein, Barbara Cohen, Catriona MacCallum, Hemai Parthasarathy, Mark Patterson, and Vivian Siegel
PLoS Biol. 2003 October; 1(1): e34. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000034.
PMCID: PMC212705
Synopses
Functional Analysis of RSS Spacers
PLoS Biol. 2003 October; 1(1): e4. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000004.
PMCID: PMC212688
Borneo Elephants: A High Priority for Conservation
PLoS Biol. 2003 October; 1(1): e7. Published online 2003 August 18. doi: 10.1371/journal.pbio.0000007.
PMCID: PMC176547
Monitoring Malaria: Genomic Activity of the Parasite in Human Blood Cells
PLoS Biol. 2003 October; 1(1): e11. Published online 2003 August 18. doi: 10.1371/journal.pbio.0000011.
PMCID: PMC176548
Biological Clock Depends on Many Parts Working Together
PLoS Biol. 2003 October; 1(1): e23. Published online 2003 September 15. doi: 10.1371/journal.pbio.0000023.
PMCID: PMC193606
Developmental Origins and Evolution of Buchnera Host Cells
PLoS Biol. 2003 October; 1(1): e24. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000024.
PMCID: PMC212700
Supersensitive Worms Reveal New Gene Functions
PLoS Biol. 2003 October; 1(1): e26. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000026.
PMCID: PMC212701
Large-Scale Association Study Confirms Genetic Complexity Underlying Type 2 Diabetes
PLoS Biol. 2003 October; 1(1): e30. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000030.
PMCID: PMC212703
New Genomic Approach Predicts True Evolutionary History of Bacterial Genomes
PLoS Biol. 2003 October; 1(1): e31. Published online 2003 September 15. doi: 10.1371/journal.pbio.0000031.
PMCID: PMC193607
Mathematical Modeling Predicts How Proteins Affect Cellular Communication
PLoS Biol. 2003 October; 1(1): e32. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000032.
PMCID: PMC212704
Essay
Neuroscience Networks: Data-sharing in an Information Age
Thomas R Insel, Nora D Volkow, Ting-Kai Li, James F Battey, Jr, and Story C Landis
PLoS Biol. 2003 October; 1(1): e17. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000017.
PMCID: PMC212696
Features
Genetically Modified Corn— Environmental Benefits and Risks
Virginia Gewin
PLoS Biol. 2003 October; 1(1): e8. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000008.
PMCID: PMC212689
Digital Evolution
Bill O'Neill
PLoS Biol. 2003 October; 1(1): e18. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000018.
PMCID: PMC212697
Unsolved Mystery
What Controls Variation in Human Skin Color?
Gregory S Barsh
PLoS Biol. 2003 October; 1(1): e27. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000027.
PMCID: PMC212702
Journal Club
Heterochromatin Dynamics
Tobias Straub
PLoS Biol. 2003 October; 1(1): e14. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000014.
PMCID: PMC212693
Primer
Microarray Analysis: Genome-scale hypothesis scanning
Greg Gibson
PLoS Biol. 2003 October; 1(1): e15. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000015.
PMCID: PMC212694
V(D)J Recombination and the Evolution of the Adaptive Immune System
Eleonora Market and F. Nina Papavasiliou
PLoS Biol. 2003 October; 1(1): e16. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000016.
PMCID: PMC212695
Community Page
Out of the Way: How the next copyright revolution can help the next scientific revolution
Glenn Otis Brown
PLoS Biol. 2003 October; 1(1): e9. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000009.
PMCID: PMC212690
Research Articles
A Functional Analysis of the Spacer of V(D)J Recombination Signal Sequences
Alfred Ian Lee, Sebastian D Fugmann, Lindsay G Cowell, Leon M Ptaszek, Garnett Kelsoe, and David G Schatz
PLoS Biol. 2003 October; 1(1): e1. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000001.
PMCID: PMC212687
The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum
Zbynek Bozdech, Manuel Llinás, Brian Lee Pulliam, Edith D Wong, Jingchun Zhu, and Joseph L DeRisi
PLoS Biol. 2003 October; 1(1): e5. Published online 2003 August 18. doi: 10.1371/journal.pbio.0000005.
PMCID: PMC176545
DNA Analysis Indicates That Asian Elephants Are Native to Borneo and Are Therefore a High Priority for Conservation
Prithiviraj Fernando, T. N. C Vidya, John Payne, Michael Stuewe, Geoffrey Davison, Raymond J Alfred, Patrick Andau, Edwin Bosi, Annelisa Kilbourn, and Don J Melnick
PLoS Biol. 2003 October; 1(1): e6. Published online 2003 August 18. doi: 10.1371/journal.pbio.0000006.
PMCID: PMC176546
The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway
Ethan Lee, Adrian Salic, Roland Krüger, Reinhart Heinrich, and Marc W Kirschner
PLoS Biol. 2003 October; 1(1): e10. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000010.
PMCID: PMC212691
Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions
Femke Simmer, Celine Moorman, Alexander M van der Linden, Ewart Kuijk, Peter V.E van den Berghe, Ravi S Kamath, Andrew G Fraser, Julie Ahringer, and Ronald H. A Plasterk
PLoS Biol. 2003 October; 1(1): e12. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000012.
PMCID: PMC212692
Drosophila Free-Running Rhythms Require Intercellular Communication
Ying Peng, Dan Stoleru, Joel D Levine, Jeffrey C Hall, and Michael Rosbash
PLoS Biol. 2003 October; 1(1): e13. Published online 2003 September 15. doi: 10.1371/journal.pbio.0000013.
PMCID: PMC193604
From Gene Trees to Organismal Phylogeny in Prokaryotes:The Case of the γ-Proteobacteria
Emmanuelle Lerat, Vincent Daubin, and Nancy A Moran
PLoS Biol. 2003 October; 1(1): e19. Published online 2003 September 15. doi: 10.1371/journal.pbio.0000019.
PMCID: PMC193605
Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action
Inês Barroso, Jian'an Luan, Rita P. S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, David Clayton, Alan J Schafer, Stephen O'Rahilly, and Nicholas J Wareham
PLoS Biol. 2003 October; 1(1): e20. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000020.
PMCID: PMC212698
Developmental Origin and Evolution of Bacteriocytes in the Aphid–Buchnera Symbiosis
Christian Braendle, Toru Miura, Ryan Bickel, Alexander W Shingleton, Srinivas Kambhampati, and David L Stern
PLoS Biol. 2003 October; 1(1): e21. Published online 2003 October 13. doi: 10.1371/journal.pbio.0000021.
PMCID: PMC212699
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