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Volume 102(5);  February 1, 2005
In This Issue
This Week in PNAS
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1265–1266. doi: 10.1073/iti0505102.
PMCID: PMC547895
Commentaries
A new mechanism for immunologic initiation of asthma
Allen P. Kaplan
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1267–1268. Published online 2005 January 26. doi: 10.1073/pnas.0409828102.
PMCID: PMC547894
Perinatal imprinting by estrogen and adult prostate disease
Olle Söder
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1269–1270. Published online 2005 January 26. doi: 10.1073/pnas.0409703102.
PMCID: PMC547893
Bacterial subversion of the host secretory pathway
Craig R. Roy
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1271–1272. Published online 2005 January 26. doi: 10.1073/pnas.0409531101.
PMCID: PMC547872
Mistakes in translation don't translate into termination
Randall A. Hughes and Andrew D. Ellington
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1273–1274. Published online 2005 January 26. doi: 10.1073/pnas.0409443101.
PMCID: PMC547853
The ups and downs of gene expression and retroviral DNA integration
Alan Engelman
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1275–1276. Published online 2005 January 26. doi: 10.1073/pnas.0409587101.
PMCID: PMC547887
Physical Sciences
Applied Mathematics
An Eulerian path approach to local multiple alignment for DNA sequences
Yu Zhang and Michael S. Waterman
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1285–1290. Published online 2005 January 24. doi: 10.1073/pnas.0409240102.
PMCID: PMC547885
Chemistry
Biography of Louis E. Brus
Tinsley Davis
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1277–1279. Published online 2005 January 26. doi: 10.1073/pnas.0409555102.
PMCID: PMC547879
Optical forces between metallic particles
A. J. Hallock, P. L. Redmond, and L. E. Brus
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1280–1284. Published online 2005 January 12. doi: 10.1073/pnas.0408604101.
PMCID: PMC547848
Regular multicharged transient soft matter in Coulomb explosion of heteroclusters
Isidore Last and Joshua Jortner
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1291–1295. Published online 2005 January 21. doi: 10.1073/pnas.0408636102.
PMCID: PMC547852
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells
Douglass Wu, Guo-Wen Xing, Michael A. Poles, Amir Horowitz, Yuki Kinjo, Barbara Sullivan, Vera Bodmer-Narkevitch, Oliver Plettenburg, Mitchell Kronenberg, Moriya Tsuji, David D. Ho, and Chi-Huey Wong
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1351–1356. Published online 2005 January 21. doi: 10.1073/pnas.0408696102.
PMCID: PMC547854
Engineering
Microengineered hydromechanical cochlear model
Robert D. White and Karl Grosh
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1296–1301. Published online 2005 January 21. doi: 10.1073/pnas.0407446102.
PMCID: PMC547842
Geology
Feedbacks and the coevolution of plants and atmospheric CO2
David J. Beerling and Robert A. Berner
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1302–1305. Published online 2005 January 24. doi: 10.1073/pnas.0408724102.
PMCID: PMC547859
Geophysics
Short-lived chlorine-36 in a Ca- and Al-rich inclusion from the Ningqiang carbonaceous chondrite
Yangting Lin, Yunbin Guan, Laurie A. Leshin, Ziyuan Ouyang, and Daode Wang
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1306–1311. Published online 2005 January 25. doi: 10.1073/pnas.0407173101.
PMCID: PMC547833
Biological Sciences
Anthropology
Gene flow across linguistic boundaries in Native North American populations
Keith Hunley and Jeffrey C. Long
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1312–1317. Published online 2005 January 24. doi: 10.1073/pnas.0409301102.
PMCID: PMC547813
Applied Biological Sciences
Genes for direct methylation of glycine provide high levels of glycinebetaine and abiotic-stress tolerance in Synechococcus and Arabidopsis
Rungaroon Waditee, Md. Nazmul H. Bhuiyan, Vandna Rai, Kenji Aoki, Yoshito Tanaka, Takashi Hibino, Shigetoshi Suzuki, Jun Takano, André T. Jagendorf, Tetsuko Takabe, and Teruhiro Takabe
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1318–1323. Published online 2005 January 21. doi: 10.1073/pnas.0409017102.
PMCID: PMC547866
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
Mitchell D. Knutson, Mohamed Oukka, Lindsey M. Koss, Fikret Aydemir, and Marianne Wessling-Resnick
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1324–1328. Published online 2005 January 21. doi: 10.1073/pnas.0409409102.
PMCID: PMC547844
Biochemistry
Chromatin remodeling by DNA bending, not twisting
Yahli Lorch, Barbara Davis, and Roger D. Kornberg
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1329–1332. Published online 2005 January 26. doi: 10.1073/pnas.0409413102.
PMCID: PMC546017
ATP-driven stepwise rotation of FoF1-ATP synthase
Hiroshi Ueno, Toshiharu Suzuki, Kazuhiko Kinosita, Jr., and Masasuke Yoshida
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1333–1338. Published online 2005 January 24. doi: 10.1073/pnas.0407857102.
PMCID: PMC545493
Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator
Paul Labhart, Sudipan Karmakar, Eleni M. Salicru, Brian S. Egan, Vassilios Alexiadis, Bert W. O'Malley, and Carolyn L. Smith
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1339–1344. Published online 2005 January 26. doi: 10.1073/pnas.0409578102.
PMCID: PMC547886
Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)
Erin Convery, Euy Kyun Shin, Qi Ding, Wei Wang, Pauline Douglas, Laurie S. Davis, Jac A. Nickoloff, Susan P. Lees-Miller, and Katheryn Meek
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1345–1350. Published online 2005 January 24. doi: 10.1073/pnas.0406466102.
PMCID: PMC547837
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells
Douglass Wu, Guo-Wen Xing, Michael A. Poles, Amir Horowitz, Yuki Kinjo, Barbara Sullivan, Vera Bodmer-Narkevitch, Oliver Plettenburg, Mitchell Kronenberg, Moriya Tsuji, David D. Ho, and Chi-Huey Wong
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1351–1356. Published online 2005 January 21. doi: 10.1073/pnas.0408696102.
PMCID: PMC547854
Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH
Randen L. Patterson, Damian B. van Rossum, Adam I. Kaplin, Roxanne K. Barrow, and Solomon H. Snyder
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1357–1359. Published online 2005 January 26. doi: 10.1073/pnas.0409657102.
PMCID: PMC547892
Ancestry and progeny of nutrient amino acid transporters
Dmitri Y. Boudko, Andrea B. Kohn, Ella A. Meleshkevitch, Michelle K. Dasher, Theresa J. Seron, Bruce R. Stevens, and William R. Harvey
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1360–1365. Published online 2005 January 21. doi: 10.1073/pnas.0405183101.
PMCID: PMC547818
Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Takatsugu Kobayashi, Kensaku Sakamoto, Tetsuo Takimura, Ryo Sekine, Kelly Vincent, Kenji Kamata, Susumu Nishimura, and Shigeyuki Yokoyama
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1366–1371. Published online 2005 January 25. doi: 10.1073/pnas.0407039102.
PMCID: PMC547826
An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs
Jonas Noeske, Christian Richter, Marc A. Grundl, Hamid R. Nasiri, Harald Schwalbe, and Jens Wöhnert
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1372–1377. Published online 2005 January 21. doi: 10.1073/pnas.0406347102.
PMCID: PMC547832
Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole
L. Wayne Schultz, Liyun Liu, Margaret Cegielski, and J. Woodland Hastings
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1378–1383. Published online 2005 January 21. doi: 10.1073/pnas.0409335102.
PMCID: PMC547824
Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice
WonKeun Oh, Lutfi Abu-Elheiga, Parichher Kordari, Zeiwei Gu, Tattym Shaikenov, Subrahmanyam S. Chirala, and Salih J. Wakil
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1384–1389. Published online 2005 January 26. doi: 10.1073/pnas.0409451102.
PMCID: PMC547858
Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing
Jon A. Kenniston, Tania A. Baker, and Robert T. Sauer
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1390–1395. Published online 2005 January 25. doi: 10.1073/pnas.0409634102.
PMCID: PMC547888
Biophysics
A segment of cold shock protein directs the folding of a combinatorial protein
Stephanie de Bono, Lutz Riechmann, Eric Girard, Roger L. Williams, and Greg Winter
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1396–1401. Published online 2005 January 25. doi: 10.1073/pnas.0407298102.
PMCID: PMC547839
Statistical analysis of MPSS measurements: Application to the study of LPS-activated macrophage gene expression
G. A. Stolovitzky, A. Kundaje, G. A. Held, K. H. Duggar, C. D. Haudenschild, D. Zhou, T. J. Vasicek, K. D. Smith, A. Aderem, and J. C. Roach
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1402–1407. Published online 2005 January 24. doi: 10.1073/pnas.0406555102.
PMCID: PMC547838
Gating of acetylcholine receptor channels: Brownian motion across a broad transition state
Anthony Auerbach
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1408–1412. Published online 2005 January 21. doi: 10.1073/pnas.0406787102.
PMCID: PMC547815
Enthalpy of helix–coil transition: Missing link in rationalizing the thermodynamics of helix-forming propensities of the amino acid residues
John M. Richardson, Maria M. Lopez, and George I. Makhatadze
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1413–1418. Published online 2005 January 25. doi: 10.1073/pnas.0408004102.
PMCID: PMC547846
Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time
L. Stirling Churchman, Zeynep Ökten, Ronald S. Rock, John F. Dawson, and James A. Spudich
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1419–1423. Published online 2005 January 24. doi: 10.1073/pnas.0409487102.
PMCID: PMC545495
A push-pull mechanism for regulating integrin function
Wei Li, Douglas G. Metcalf, Roman Gorelik, Renhao Li, Neal Mitra, Vikas Nanda, Peter B. Law, James D. Lear, William F. DeGrado, and Joel S. Bennett
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1424–1429. Published online 2005 January 25. doi: 10.1073/pnas.0409334102.
PMCID: PMC547819
From the Cover:
Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
Carlos W. Bertoncini, Young-Sang Jung, Claudio O. Fernandez, Wolfgang Hoyer, Christian Griesinger, Thomas M. Jovin, and Markus Zweckstetter
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1430–1435. Published online 2005 January 25. doi: 10.1073/pnas.0407146102.
PMCID: PMC547830
Cell Biology
From the Cover:
Relationship between retroviral DNA-integration-site selection and host cell transcription
Lori F. Maxfield, Camilla D. Fraize, and John M. Coffin
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1436–1441. Published online 2005 January 19. doi: 10.1073/pnas.0409204102.
PMCID: PMC547878
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
Jihee Kim, Seungkirl Ahn, Xiu-Rong Ren, Erin J. Whalen, Eric Reiter, Huijun Wei, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1442–1447. Published online 2005 January 25. doi: 10.1073/pnas.0409532102.
PMCID: PMC547874
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
Xiu-Rong Ren, Eric Reiter, Seungkirl Ahn, Jihee Kim, Wei Chen, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1448–1453. Published online 2005 January 25. doi: 10.1073/pnas.0409534102.
PMCID: PMC547876
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo
Amjad Javed, George L. Barnes, Jitesh Pratap, Tomasz Antkowiak, Louis C. Gerstenfeld, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, and Gary S. Stein
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1454–1459. Published online 2005 January 21. doi: 10.1073/pnas.0409121102.
PMCID: PMC547873
The Wnt/β-catenin signaling pathway targets PPARγ activity in colon cancer cells
Emmelie Å. Jansson, Alexandra Are, Gediminas Greicius, I-Chun Kuo, Denise Kelly, Velmurugesan Arulampalam, and Sven Pettersson
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1460–1465. Published online 2005 January 21. doi: 10.1073/pnas.0405928102.
PMCID: PMC547827
A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways
Darren Boehning, Damian B. van Rossum, Randen L. Patterson, and Solomon H. Snyder
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1466–1471. Published online 2005 January 21. doi: 10.1073/pnas.0409650102.
PMCID: PMC547891
Blebbistatin and blebbistatin-inactivated myosin II inhibit myosin II-independent processes in Dictyostelium
Shi Shu, Xiong Liu, and Edward D. Korn
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1472–1477. Published online 2005 January 25. doi: 10.1073/pnas.0409528102.
PMCID: PMC547870
The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production
Iris Alroy, Shmuel Tuvia, Tsvika Greener, Daphna Gordon, Haim M. Barr, Daniel Taglicht, Revital Mandil-Levin, Danny Ben-Avraham, Dalit Konforty, Anat Nir, Orit Levius, Vivian Bicoviski, Mally Dori, Shenhav Cohen, Liora Yaar, Omri Erez, Oshrat Propheta-Meiran, Mordechai Koskas, Elanite Caspi-Bachar, Iris Alchanati, Alin Sela-Brown, Haim Moskowitz, Uwe Tessmer, Ulrich Schubert, and Yuval Reiss
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1478–1483. Published online 2005 January 19. doi: 10.1073/pnas.0408717102.
PMCID: PMC545085
Developmental Biology
Estrogen receptor α and imprinting of the neonatal mouse ventral prostate by estrogen
Yoko Omoto, Otabek Imamov, Margaret Warner, and Jan-Åke Gustafsson
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1484–1489. Published online 2005 January 21. doi: 10.1073/pnas.0409168102.
PMCID: PMC547875
Lack of TCF2/vHNF1 in mice leads to pancreas agenesis
C. Haumaitre, E. Barbacci, M. Jenny, M. O. Ott, G. Gradwohl, and S. Cereghini
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1490–1495. Published online 2005 January 24. doi: 10.1073/pnas.0405776102.
PMCID: PMC547822
Supernumerary neuromasts in the posterior lateral line of zebrafish lacking peripheral glia
Hernán López-Schier and A. J. Hudspeth
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1496–1501. Published online 2005 January 26. doi: 10.1073/pnas.0409361102.
PMCID: PMC547829
Laminin α1 globular domains 4–5 induce fetal development but are not vital for embryonic basement membrane assembly
Susanne Schéele, Mats Falk, Ahnders Franzén, Fredrik Ellin, Maria Ferletta, Peter Lonai, Björn Andersson, Rupert Timpl, Erik Forsberg, and Peter Ekblom
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1502–1506. Published online 2005 January 24. doi: 10.1073/pnas.0405095102.
PMCID: PMC545491
Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans
Tarja Kinnunen, Zebo Huang, Joanne Townsend, Michelle M. Gatdula, Jillian R. Brown, Jeffrey D. Esko, and Jeremy E. Turnbull
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1507–1512. Published online 2005 January 25. doi: 10.1073/pnas.0401591102.
PMCID: PMC547812
The DNA/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells
Juxiang Yang, Sergey Medvedev, P. Prabhakara Reddi, Richard M. Schultz, and Norman B. Hecht
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1513–1518. Published online 2005 January 21. doi: 10.1073/pnas.0404685102.
PMCID: PMC547816
Ecology
Soil animals alter plant litter diversity effects on decomposition
Stephan Hättenschwiler and Patrick Gasser
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1519–1524. Published online 2005 January 25. doi: 10.1073/pnas.0404977102.
PMCID: PMC547817
Stable isotopes (δ13C and δ15N) of organic matrix from coral skeleton
Leonard Muscatine, Claire Goiran, Lynton Land, Jean Jaubert, Jean-Pierre Cuif, and Denis Allemand
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1525–1530. Published online 2005 January 25. doi: 10.1073/pnas.0408921102.
PMCID: PMC547863
Host population persistence in the face of introduced vector-borne diseases: Hawaii amakihi and avian malaria
Bethany L. Woodworth, Carter T. Atkinson, Dennis A. LaPointe, Patrick J. Hart, Caleb S. Spiegel, Erik J. Tweed, Carlene Henneman, Jaymi LeBrun, Tami Denette, Rachel DeMots, Kelly L. Kozar, Dennis Triglia, Dan Lease, Aaron Gregor, Tom Smith, and David Duffy
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1531–1536. Published online 2005 January 24. doi: 10.1073/pnas.0409454102.
PMCID: PMC547860
Evolution
The position of Hippopotamidae within Cetartiodactyla
Jean-Renaud Boisserie, Fabrice Lihoreau, and Michel Brunet
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1537–1541. Published online 2005 January 26. doi: 10.1073/pnas.0409518102.
PMCID: PMC547867
A genomic population genetics analysis of the pathogenic enterocyte effacement island in Escherichia coli: The search for the unit of selection
Amanda Castillo, Luis E. Eguiarte, and Valeria Souza
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1542–1547. Published online 2005 January 24. doi: 10.1073/pnas.0408633102.
PMCID: PMC547851
The diversity of dolichol-linked precursors to Asn-linked glycans likely results from secondary loss of sets of glycosyltransferases
John Samuelson, Sulagna Banerjee, Paula Magnelli, Jike Cui, Daniel J. Kelleher, Reid Gilmore, and Phillips W. Robbins
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1548–1553. Published online 2005 January 21. doi: 10.1073/pnas.0409460102.
PMCID: PMC545090
From the Cover:
Reconstructing early sponge relationships by using the Burgess Shale fossil Eiffelia globosa, Walcott
Joseph P. Botting and Nicholas J. Butterfield
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1554–1559. Published online 2005 January 21. doi: 10.1073/pnas.0405867102.
PMCID: PMC547825
Genetics
Identifying tissue-selective transcription factor binding sites in vertebrate promoters
Andrew D. Smith, Pavel Sumazin, and Michael Q. Zhang
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1560–1565. Published online 2005 January 24. doi: 10.1073/pnas.0406123102.
PMCID: PMC547828
A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome
Mark Yandell, Adina M. Bailey, Sima Misra, ShengQiang Shu, Colin Wiel, Martha Evans-Holm, Susan E. Celniker, and Gerald M. Rubin
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1566–1571. Published online 2005 January 24. doi: 10.1073/pnas.0409421102.
PMCID: PMC545494
The landscape of genetic complexity across 5,700 gene expression traits in yeast
Rachel B. Brem and Leonid Kruglyak
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1572–1577. Published online 2005 January 19. doi: 10.1073/pnas.0408709102.
PMCID: PMC547855
Immunology
From the Cover:
Elicitation of allergic asthma by immunoglobulin free light chains
Aletta D. Kraneveld, Mirjam Kool, Anneke H. van Houwelingen, Paul Roholl, Alan Solomon, Dirkje S. Postma, Frans P. Nijkamp, and Frank A. Redegeld
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1578–1583. Published online 2005 January 14. doi: 10.1073/pnas.0406808102.
PMCID: PMC547820
Nibrin functions in Ig class-switch recombination
Sven Kracker, Yvonne Bergmann, Ilja Demuth, Pierre-Olivier Frappart, Gabriele Hildebrand, Rainer Christine, Zhao-Qi Wang, Karl Sperling, Martin Digweed, and Andreas Radbruch
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1584–1589. Published online 2005 January 24. doi: 10.1073/pnas.0409191102.
PMCID: PMC547877
Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1
Bernardo Reina-San-Martin, Michel C. Nussenzweig, André Nussenzweig, and Simone Difilippantonio
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1590–1595. Published online 2005 January 24. doi: 10.1073/pnas.0406289102.
PMCID: PMC547831
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses
Chiara Buono, Christoph J. Binder, George Stavrakis, Joseph L. Witztum, Laurie H. Glimcher, and Andrew H. Lichtman
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1596–1601. Published online 2005 January 21. doi: 10.1073/pnas.0409015102.
PMCID: PMC547865
A PKR-like eukaryotic initiation factor 2α kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains
Stefan Rothenburg, Nikolaus Deigendesch, Katharina Dittmar, Friedrich Koch-Nolte, Friedrich Haag, Ky Lowenhaupt, and Alexander Rich
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1602–1607. Published online 2005 January 19. doi: 10.1073/pnas.0408714102.
PMCID: PMC547857
Receptor editing in peripheral B cell tolerance
Jeffrey S. Rice, Jeffrey Newman, Chuansheng Wang, Daniel J. Michael, and Betty Diamond
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1608–1613. Published online 2005 January 19. doi: 10.1073/pnas.0409217102.
PMCID: PMC547880
Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin αXβ2
Thomas Vorup-Jensen, Christopher V. Carman, Motomu Shimaoka, Peter Schuck, Juraj Svitel, and Timothy A. Springer
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1614–1619. Published online 2005 January 21. doi: 10.1073/pnas.0409057102.
PMCID: PMC547869
Peptide 15-mers of defined sequence that substitute for random amino acid copolymers in amelioration of experimental autoimmune encephalomyelitis
Joel N. H. Stern, Zsolt Illés, Jayagopala Reddy, Derin B. Keskin, Masha Fridkis-Hareli, Vijay K. Kuchroo, and Jack L. Strominger
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1620–1625. Published online 2005 January 21. doi: 10.1073/pnas.0409022102.
PMCID: PMC547868
Unparalleled complexity of the MHC class I region in rhesus macaques
Nel Otting, Corrine M. C. Heijmans, Riet C. Noort, Natasja G. de Groot, Gaby G. M. Doxiadis, Jon J. van Rood, David I. Watkins, and Ronald E. Bontrop
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1626–1631. Published online 2005 January 21. doi: 10.1073/pnas.0409084102.
PMCID: PMC545086
Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells
Caius G. Radu, Amar Nijagal, Jami McLaughlin, Li Wang, and Owen N. Witte
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1632–1637. Published online 2005 January 21. doi: 10.1073/pnas.0409415102.
PMCID: PMC545089
Medical Sciences
Requirement of phospholipase D1 activity in H-RasV12-induced transformation
F. Gregory Buchanan, Matt McReynolds, Anthony Couvillon, Yoonseok Kam, Vijaykumar R. Holla, Raymond N. DuBois, and John H. Exton
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1638–1642. Published online 2005 January 24. doi: 10.1073/pnas.0406698102.
PMCID: PMC547811
Accessing key steps of human tumor progression in vivo by using an avian embryo model
Martin Hagedorn, Sophie Javerzat, Delphine Gilges, Aurélie Meyre, Benjamin de Lafarge, Anne Eichmann, and Andreas Bikfalvi
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1643–1648. Published online 2005 January 21. doi: 10.1073/pnas.0408622102.
PMCID: PMC547849
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation
Haojie Huang, Kevin M. Regan, Fang Wang, Diping Wang, David I Smith, Jan M. A. van Deursen, and Donald J. Tindall
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1649–1654. Published online 2005 January 24. doi: 10.1073/pnas.0406789102.
PMCID: PMC545492
Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc
Joerg Heineke, Hartmut Ruetten, Christian Willenbockel, Sandra C. Gross, Marian Naguib, Arnd Schaefer, Tibor Kempf, Denise Hilfiker-Kleiner, Pico Caroni, Theresia Kraft, Robert A. Kaiser, Jeffery D. Molkentin, Helmut Drexler, and Kai C. Wollert
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1655–1660. Published online 2005 January 21. doi: 10.1073/pnas.0405488102.
PMCID: PMC547821
Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism
Hunter C. Champion, Trinity J. Bivalacqua, Eiki Takimoto, David A. Kass, and Arthur L. Burnett
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1661–1666. Published online 2005 January 24. doi: 10.1073/pnas.0407183102.
PMCID: PMC547836
BDNF modulates GABAA receptors microtransplanted from the human epileptic brain to Xenopus oocytes
E. Palma, G. Torchia, C. Limatola, F. Trettel, A. Arcella, G. Cantore, G. Di Gennaro, M. Manfredi, V. Esposito, P. P. Quarato, R. Miledi, and F. Eusebi
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1667–1672. Published online 2005 January 21. doi: 10.1073/pnas.0409442102.
PMCID: PMC547850
Microbiology
From the Cover:
Brucella coopts the small GTPase Sar1 for intracellular replication
Jean Celli, Suzana P. Salcedo, and Jean-Pierre Gorvel
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1673–1678. Published online 2005 January 4. doi: 10.1073/pnas.0406873102.
PMCID: PMC547823
Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response
Paul Sumby, Kent D. Barbian, Donald J. Gardner, Adeline R. Whitney, Diane M. Welty, R. Daniel Long, John R. Bailey, Michael J. Parnell, Nancy P. Hoe, Gerald G. Adams, Frank R. DeLeo, and James M. Musser
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1679–1684. Published online 2005 January 24. doi: 10.1073/pnas.0406641102.
PMCID: PMC547841
Predicted hexameric structure of the Agrobacterium VirB4 C terminus suggests VirB4 acts as a docking site during type IV secretion
Rebecca Middleton, Kimmen Sjölander, Nandini Krishnamurthy, Jonathan Foley, and Patricia Zambryski
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1685–1690. Published online 2005 January 24. doi: 10.1073/pnas.0409399102.
PMCID: PMC547840
Transient interference with staphylococcal quorum sensing blocks abscess formation
Jesse S. Wright, III, Rhuzong Jin, and Richard P. Novick
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1691–1696. Published online 2005 January 21. doi: 10.1073/pnas.0407661102.
PMCID: PMC547845
Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase
Jamie M. Bacher, Valérie de Crécy-Lagard, and Paul R. Schimmel
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1697–1701. Published online 2005 January 12. doi: 10.1073/pnas.0409064102.
PMCID: PMC547871
Seasonal epidemics of cholera inversely correlate with the prevalence of environmental cholera phages
Shah M. Faruque, Iftekhar Bin Naser, M. Johirul Islam, A. S. G. Faruque, A. N. Ghosh, G. Balakrish Nair, David A. Sack, and John J. Mekalanos
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1702–1707. Published online 2005 January 14. doi: 10.1073/pnas.0408992102.
PMCID: PMC547864
Neuroscience
Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid
Max H. Nanao, Tim Green, Yael Stern-Bach, Stephen F. Heinemann, and Senyon Choe
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1708–1713. Published online 2005 January 26. doi: 10.1073/pnas.0409573102.
PMCID: PMC547884
Role of SDF1 chemokine in the development of lateral line efferent and facial motor neurons
Dora Sapède, Mireille Rossel, Christine Dambly-Chaudière, and Alain Ghysen
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1714–1718. Published online 2005 January 19. doi: 10.1073/pnas.0406382102.
PMCID: PMC547835
Differential contribution of the three Aph1 genes to γ-secretase activity in vivo
Lutgarde Serneels, Tim Dejaegere, Katleen Craessaerts, Katrien Horré, Ellen Jorissen, Thomas Tousseyn, Sébastien Hébert, Marcel Coolen, Gerard Martens, An Zwijsen, Wim Annaert, Dieter Hartmann, and Bart De Strooper
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1719–1724. Published online 2005 January 21. doi: 10.1073/pnas.0408901102.
PMCID: PMC547495
Mu-opioid receptors modulate the stability of dendritic spines
Dezhi Liao, Hang Lin, Ping Yee Law, and Horace H. Loh
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1725–1730. Published online 2005 January 19. doi: 10.1073/pnas.0406797102.
PMCID: PMC545084
The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton
Gianluca Cestra, Derek Toomre, Sunghoe Chang, and Pietro De Camilli
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1731–1736. Published online 2005 January 19. doi: 10.1073/pnas.0409376102.
PMCID: PMC547834
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling
Satoru Takahashi, Toshio Ohshima, Andrew Cho, Taduru Sreenath, Michael J. Iadarola, Harish C. Pant, Yong Kim, Angus C. Nairn, Roscoe O. Brady, Paul Greengard, and Ashok B. Kulkarni
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1737–1742. Published online 2005 January 21. doi: 10.1073/pnas.0409456102.
PMCID: PMC547862
Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep
Matthew P. Anderson, Takatoshi Mochizuki, Jinghui Xie, Walter Fischler, Jules P. Manger, Edmund M. Talley, Thomas E. Scammell, and Susumu Tonegawa
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1743–1748. Published online 2005 January 26. doi: 10.1073/pnas.0409644102.
PMCID: PMC547889
DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures
Jai Sung Noh, Rajiv P. Sharma, Marin Veldic, Alain A. Salvacion, Xiaomei Jia, Ying Chen, Erminio Costa, Alessandro Guidotti, and Dennis R. Grayson
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1749–1754. Published online 2005 January 25. doi: 10.1073/pnas.0409648102.
PMCID: PMC547890
Pharmacology
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice
T. M. Cunha, W. A. Verri, Jr., J. S. Silva, S. Poole, F. Q. Cunha, and S. H. Ferreira
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1755–1760. Published online 2005 January 21. doi: 10.1073/pnas.0409225102.
PMCID: PMC547882
Physiology
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54
Sophie Messager, Emmanouella E. Chatzidaki, Dan Ma, Alan G. Hendrick, Dirk Zahn, John Dixon, Rosemary R. Thresher, Isabelle Malinge, Didier Lomet, Mark B. L. Carlton, William H. Colledge, Alain Caraty, and Samuel A. J. R. Aparicio
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1761–1766. Published online 2005 January 21. doi: 10.1073/pnas.0409330102.
PMCID: PMC545088
Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart
Xinxin Yu, Shawn C. Burgess, Hongfei Ge, Kenny K. Wong, R. Haris Nassem, Daniel J. Garry, A. Dean Sherry, Craig R. Malloy, Joel P. Berger, and Cai Li
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1767–1772. Published online 2005 January 19. doi: 10.1073/pnas.0409564102.
PMCID: PMC547881
Plant Biology
Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
Farhad Forouhar, Yue Yang, Dhirendra Kumar, Yang Chen, Eyal Fridman, Sang Wook Park, Yiwen Chiang, Thomas B. Acton, Gaetano T. Montelione, Eran Pichersky, Daniel F. Klessig, and Liang Tong
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1773–1778. Published online 2005 January 24. doi: 10.1073/pnas.0409227102.
PMCID: PMC547883
Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome
Charlotte Kristensen, Marc Morant, Carl Erik Olsen, Claus T. Ekstrøm, David W. Galbraith, Birger Lindberg Møller, and Søren Bak
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1779–1784. Published online 2005 January 21. doi: 10.1073/pnas.0409233102.
PMCID: PMC545087
α-Glucan, water dikinase (GWD): A plastidic enzyme with redox-regulated and coordinated catalytic activity and binding affinity
René Mikkelsen, Kudzai E. Mutenda, Alexandra Mant, Peter Schürmann, and Andreas Blennow
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1785–1790. Published online 2005 January 21. doi: 10.1073/pnas.0406674102.
PMCID: PMC547843
Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores
Jianping Cui, Adam K. Bahrami, Elizabeth G. Pringle, Gustavo Hernandez-Guzman, Carol L. Bender, Naomi E. Pierce, and Frederick M. Ausubel
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1791–1796. Published online 2005 January 18. doi: 10.1073/pnas.0409450102.
PMCID: PMC547856
Psychology
Fast decay of iconic memory in observers with mild cognitive impairments
Zhong-Lin Lu, James Neuse, Stephen Madigan, and Barbara Anne Dosher
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1797–1802. Published online 2005 January 21. doi: 10.1073/pnas.0408402102.
PMCID: PMC547847
Social Sciences
Psychology
Experiments investigating cooperative types in humans: A complement to evolutionary theory and simulations
Robert Kurzban and Daniel Houser
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1803–1807. Published online 2005 January 21. doi: 10.1073/pnas.0408759102.
PMCID: PMC547861
Correction
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1808. Published online 2005 January 21. doi: 10.1073/pnas.0404043102.
PMCID: PMC547814
Corrects: David N. Levy, et al. From the Cover:
Dynamics of HIV-1 recombination in its natural target cells.
Proc Natl Acad Sci U S A. 2004 March 23; 101(12): 4204–4209.
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