| | This journal provides immediate access to some articles. Commentaries Tox-boxes, fungal secondary metabolites, and plant disease Anne E. Osbourn PMCID: PMC64654 Dissecting the transcriptional network of pancreatic islets
during development and differentiation David Q. Shih and Markus Stoffel PMCID: PMC64655 Surprises from the airway epithelium Landon S. King PMCID: PMC64656 Another protozoan contributes to understanding telomeres and
transposable elements Mary-Lou Pardue, P. G. DeBaryshe, and Ky Lowenhaupt PMCID: PMC64657 Physical Sciences Applied Mathematics Conservative front tracking and level set algorithms James Glimm, Xiao Lin Li, Yingjie Liu, and Ning Zhao PMCID: PMC64658 Applied Physical Sciences Pattern formation in Escherichia coli: A model for
the pole-to-pole oscillations of Min proteins and the localization of
the division site Hans Meinhardt and Piet A. J. de Boer PMCID: PMC64659 Pulse confinement in optical fibers with random dispersion M. Chertkov, I. Gabitov, and J. Moeser PMCID: PMC64660 Chemistry The anticancer drug–DNA complex: Femtosecond primary dynamics
for anthracycline antibiotics function Xiaogang Qu, Chaozhi Wan, Hans-Christian Becker, Dongping Zhong, and Ahmed H. Zewail PMCID: PMC64661 Geology Rapid shoreward encroachment of salt marsh cordgrass in response
to accelerated sea-level rise Jeffrey P. Donnelly and Mark D. Bertness PMCID: PMC64662 Physics A possible loophole in the theorem of Bell Karl Hess and Walter Philipp PMCID: PMC64663 Bell's theorem and the problem of decidability between the views
of Einstein and Bohr Karl Hess and Walter Philipp PMCID: PMC64664 Spectroscopic studies of the vibrational and electronic
properties of solid hydrogen to 285 GPa Alexander F. Goncharov, Eugene Gregoryanz, Russell J. Hemley, and Ho-kwang Mao PMCID: PMC64665 Biological Sciences Applied Biological Sciences Detection of DNA point mutations and mRNA expression levels by
rolling circle amplification in individual cells Allen T. Christian, Melissa S. Pattee, Christina M. Attix, Beth E. Reed, Karen J. Sorensen, and James D. Tucker PMCID: PMC64666 Biochemistry Binding specificity of Escherichia coli trigger
factor Holger Patzelt, Stefan Rüdiger, Dirk Brehmer, Günter Kramer, Sonja Vorderwülbecke, Elke Schaffitzel, Andreas Waitz, Thomas Hesterkamp, Liying Dong, Jens Schneider-Mergener, Bernd Bukau, and Elke Deuerling PMCID: PMC64667 Dimer formation drives the activation of the cell death protease
caspase 9 Martin Renatus, Henning R. Stennicke, Fiona L. Scott, Robert C. Liddington, and Guy S. Salvesen PMCID: PMC64668 Targeting of human DNA polymerase ι to the replication
machinery via interaction with PCNA Lajos Haracska, Robert E. Johnson, Ildiko Unk, Barbara B. Phillips, Jerard Hurwitz, Louise Prakash, and Satya Prakash PMCID: PMC64669 The ionic layer is required for efficient dissociation of the
SNARE complex by α-SNAP and NSF Suzie J. Scales, Bryan Y. Yoo, and Richard H. Scheller PMCID: PMC64670 Structure of a quinohemoprotein amine dehydrogenase with an
uncommon redox cofactor and highly unusual crosslinking Saumen Datta, Youichi Mori, Kazuyoshi Takagi, Katsunori Kawaguchi, Zhi-Wei Chen, Toshihide Okajima, Shun'ichi Kuroda, Tokuji Ikeda, Kenji Kano, Katsuyuki Tanizawa, and F. Scott Mathews PMCID: PMC64671 From the Cover:
Enzyme-like proteins by computational design Daniel N. Bolon and Stephen L. Mayo PMCID: PMC64672 Critical involvement of a carbamylated lysine in catalytic
function of class D β-lactamases Dasantila Golemi, Laurent Maveyraud, Sergei Vakulenko, Jean-Pierre Samama, and Shahriar Mobashery PMCID: PMC64673 Translation of a nonpolyadenylated viral RNA is enhanced by
binding of viral coat protein or polyadenylation of the RNA Lyda Neeleman, René C. L. Olsthoorn, Huub J. M. Linthorst, and John F. Bol PMCID: PMC64674 Cysteinyl-tRNA synthetase is not essential for viability of the
archaeon Methanococcus maripaludis Constantinos Stathopoulos, Wonduck Kim, Tong Li, Iain Anderson, Britta Deutsch, Sotiria Palioura, William Whitman, and Dieter Söll PMCID: PMC64675 Okazaki fragment processing: Modulation of the strand
displacement activity of DNA polymerase δ by the concerted action
of replication protein A, proliferating cell nuclear antigen,
and flap endonuclease-1 Giovanni Maga, Giuseppe Villani, Vanessa Tillement, Manuel Stucki, Giada A. Locatelli, Isabelle Frouin, Silvio Spadari, and Ulrich Hübscher PMCID: PMC64676 A vertebrate fatty acid desaturase with Δ5 and Δ6 activities Nicola Hastings, Morris Agaba, Douglas R. Tocher, Michael J. Leaver, James R. Dick, John R. Sargent, and Alan J. Teale PMCID: PMC64677 Import of amber and ochre suppressor tRNAs into mammalian cells:
A general approach to site-specific insertion of amino acid analogues into proteins Caroline Köhrer, Liang Xie, Susanne Kellerer, Umesh Varshney, and Uttam L. RajBhandary PMCID: PMC64678 Histone tails modulate nucleosome mobility and regulate
ATP-dependent nucleosome sliding by NURF Ali Hamiche, Ju-Gyeong Kang, Cynthia Dennis, Hua Xiao, and Carl Wu PMCID: PMC64679 A second iron-regulatory system in yeast independent of Aft1p Julian C. Rutherford, Shulamit Jaron, Esha Ray, Patrick O. Brown, and Dennis R. Winge PMCID: PMC64680 RelE, a global inhibitor of translation, is activated during
nutritional stress Susanne K. Christensen, Marie Mikkelsen, Kim Pedersen, and Kenn Gerdes PMCID: PMC64681 Differential roles of phosphorylation in the formation of
transcriptional active RNA polymerase I Stephan Fath, Philipp Milkereit, Gerald Peyroche, Michel Riva, Christophe Carles, and Herbert Tschochner PMCID: PMC64682 Specificity in transmembrane helix–helix interactions can define
a hierarchy of stability for sequence variants Karen G. Fleming and Donald M. Engelman PMCID: PMC64683 Biophysics The anticancer drug–DNA complex: Femtosecond primary dynamics
for anthracycline antibiotics function Xiaogang Qu, Chaozhi Wan, Hans-Christian Becker, Dongping Zhong, and Ahmed H. Zewail PMCID: PMC64661 Dynamic mechanisms of the membrane water channel aquaporin-1
(AQP1) Yifei Kong and Jianpeng Ma PMCID: PMC64684 Protein threading by learning Iksoo Chang, Marek Cieplak, Ruxandra I. Dima, Amos Maritan, and Jayanth R. Banavar PMCID: PMC64685 Fast dynamics of halophilic malate dehydrogenase and BSA measured
by neutron scattering under various solvent conditions influencing protein stability Moeava Tehei, Dominique Madern, Claude Pfister, and Giuseppe Zaccai PMCID: PMC64686 Global configuration of single titin molecules observed through
chain-associated rhodamine dimers László Grama, Béla Somogyi, and Miklós S. Z. Kellermayer PMCID: PMC64687 Rapid formation of the stable tyrosyl radical in photosystem II Peter Faller, Richard J. Debus, Klaus Brettel, Miwa Sugiura, A. William Rutherford, and Alain Boussac PMCID: PMC64688 NMR structure reveals intramolecular regulation mechanism
for pheromone binding and release Reto Horst, Fred Damberger, Peter Luginbühl, Peter Güntert, Guihong Peng, Larisa Nikonova, Walter S. Leal, and Kurt Wüthrich PMCID: PMC64689 Comparison of a hair bundle's spontaneous oscillations with its
response to mechanical stimulation reveals the underlying active process P. Martin, A. J. Hudspeth, and F. Jülicher PMCID: PMC64690 Compressive nonlinearity in the hair bundle's active response to
mechanical stimulation P. Martin and A. J. Hudspeth PMCID: PMC64691 The nature of fluorescence emission in the red fluorescent
protein DsRed, revealed by single-molecule detection M. F. Garcia-Parajo, M. Koopman, E. M. H. P. van Dijk, V. Subramaniam, and N. F. van Hulst PMCID: PMC64692 Identification of different emitting species in the red
fluorescent protein DsRed by means of ensemble and
single-molecule spectroscopy Mircea Cotlet, Johan Hofkens, Satoshi Habuchi, Gunter Dirix, Maarten Van Guyse, Jan Michiels, Jos Vanderleyden, and Frans C. De Schryver PMCID: PMC64693 Cell Biology Pattern formation in Escherichia coli: A model for
the pole-to-pole oscillations of Min proteins and the localization of
the division site Hans Meinhardt and Piet A. J. de Boer PMCID: PMC64659 Peripheral myelin protein 22 is a constituent of intercellular
junctions in epithelia Lucia Notterpek, Kyle J. Roux, Stephanie A. Amici, Amy Yazdanpour, Christoph Rahner, and Brad S. Fletcher PMCID: PMC64694 Radiation risk to low fluences of α particles may be greater
than we thought Hongning Zhou, Masao Suzuki, Gerhard Randers-Pehrson, Diane Vannais, Gang Chen, James E. Trosko, Charles A. Waldren, and Tom K. Hei PMCID: PMC64695 Akt/PKB regulates laminin and collagen IV isotypes of the
basement membrane Xiaofeng Li, Ulrika Talts, Jan F. Talts, Esther Arman, Peter Ekblom, and Peter Lonai PMCID: PMC64696 The tumor autocrine motility factor receptor, gp78, is a
ubiquitin protein ligase implicated in degradation from the
endoplasmic reticulum Shengyun Fang, Marco Ferrone, Cuihong Yang, Jane P. Jensen, Swati Tiwari, and Allan M. Weissman PMCID: PMC64697 Specific interference with gene expression induced by long,
double-stranded RNA in mouse embryonal teratocarcinoma cell lines Eric Billy, Vincent Brondani, Haidi Zhang, Ulrich Müller, and Witold Filipowicz PMCID: PMC64698 Analysis of mitotic microtubule-associated proteins using mass
spectrometry identifies astrin, a spindle-associated protein Gary J. Mack and Duane A. Compton PMCID: PMC64699 Atrogin-1, a muscle-specific F-box protein highly expressed
during muscle atrophy Marcelo D. Gomes, Stewart H. Lecker, R. Thomas Jagoe, Ami Navon, and Alfred L. Goldberg PMCID: PMC64700 Identification, characterization, and complete amino acid
sequence of the conjugation-inducing glycoprotein (blepharmone) in the
ciliate Blepharisma japonicum Mayumi Sugiura and Terue Harumoto PMCID: PMC64701 The LIM domain gene LMO4 inhibits
differentiation of mammary epithelial cells in vitro
and is overexpressed in breast cancer Jane E. Visvader, Deon Venter, Kyungmin Hahm, Margaret Santamaria, Eleanor Y. M. Sum, Lorraine O'Reilly, David White, Rachael Williams, Jane Armes, and Geoffrey J. Lindeman PMCID: PMC64702 Induction of platelet formation from megakaryocytoid cells by
nitric oxide Elisabeth Battinelli, Scott R. Willoughby, Thomas Foxall, C. Robert Valeri, and Joseph Loscalzo PMCID: PMC64703 Coexisting conformations of fibronectin in cell culture imaged
using fluorescence resonance energy transfer Gretchen Baneyx, Loren Baugh, and Viola Vogel PMCID: PMC64704 Developmental Biology Bazooka is required for localization of determinants and
controlling proliferation in the sensory organ precursor cell lineage
in Drosophila Fabrice Roegiers, Susan Younger-Shepherd, Lily Yeh Jan, and Yuh Nung Jan PMCID: PMC64705 Bazooka and atypical protein kinase C are required to
regulate oocyte differentiation in the Drosophila
ovary Daniel N. Cox, Salim Abdelilah Seyfried, Lily Yeh Jan, and Yuh Nung Jan PMCID: PMC64706 From the Cover:
A transcription factor regulatory circuit in differentiated
pancreatic cells Sylvia F. Boj, Marcelina Párrizas, Miguel A. Maestro, and Jorge Ferrer PMCID: PMC64707 Seven Wnt homologues in Drosophila: A case study
of the developing tracheae Marta Llimargas and Peter A. Lawrence PMCID: PMC64708 Ecology The animal species–body size distribution of Marion Island Kevin J. Gaston, Steven L. Chown, and Richard D. Mercer PMCID: PMC64709 Evolution From the Cover:
Three retrotransposon families in the genome of Giardia
lamblia: Two telomeric, one dead Irina R. Arkhipova and Hilary G. Morrison PMCID: PMC64710 Association between divergence and interspersed repeats in
mammalian noncoding genomic DNA Francesca Chiaromonte, Shan Yang, Laura Elnitski, Von Bing Yap, Webb Miller, and Ross C. Hardison PMCID: PMC64711 From the Cover:
Genetic shift in photoperiodic response correlated with
global warming William E. Bradshaw and Christina M. Holzapfel PMCID: PMC64712 A likelihood ratio test for evolutionary rate shifts and
functional divergence among proteins Bjarne Knudsen and Michael M. Miyamoto PMCID: PMC64713 Dinosaurs, dragons, and dwarfs: The evolution of maximal
body size Gary P. Burness, Jared Diamond, and Timothy Flannery PMCID: PMC64714 Genetics Meiotic recombination frequencies are affected by nutritional
states in Saccharomyces cerevisiae Mohamad F. F. Abdullah and Rhona H. Borts PMCID: PMC64715 High frequency mitotic gene conversion in genetic hybrids of the
oomycete Phytophthora sojae Jureerat Chamnanpunt, Wei-xing Shan, and Brett M. Tyler PMCID: PMC64716 Restricted chromosomal silencing in nucleolar dominance Michelle S. Lewis and Craig S. Pikaard PMCID: PMC64717 Immunology Flk-2 is a marker in hematopoietic stem cell differentiation: A
simple method to isolate long-term stem cells Julie L. Christensen and Irving L. Weissman PMCID: PMC64718 Signaling at the inhibitory natural killer cell immune synapse
regulates lipid raft polarization but not class I MHC clustering Marlys S. Fassett, Daniel M. Davis, Markus M. Valter, George B. Cohen, and Jack L. Strominger PMCID: PMC64719 Switch junction sequences in PMS2-deficient mice reveal a
microhomology-mediated mechanism of Ig class switch recombination Michael R. Ehrenstein, Cristina Rada, Anne-Marie Jones, César Milstein, and Michael S. Neuberger PMCID: PMC64720 IL-15 plays a major role in the persistence of Tax-specific CD8
cells in HAM/TSP patients Nazli Azimi, Masahiro Nagai, Steven Jacobson, and Thomas A. Waldmann PMCID: PMC64721 T cell infiltration of the prostate induced by androgen
withdrawal in patients with prostate cancer Maria Mercader, Barbara K. Bodner, Micheal T. Moser, Pamela S. Kwon, Eugene S. Y. Park, Ryan G. Manecke, Thomas M. Ellis, Eva M. Wojcik, Damu Yang, Robert C. Flanigan, W. Bedford Waters, W. Martin Kast, and Eugene D. Kwon PMCID: PMC64722 Role of SEREX-defined immunogenic wild-type cellular molecules in
the development of tumor-specific immunity Hiroyoshi Nishikawa, Koji Tanida, Hiroaki Ikeda, Miho Sakakura, Yoshihiro Miyahara, Takumi Aota, Katsumi Mukai, Masato Watanabe, Kagemasa Kuribayashi, Lloyd J. Old, and Hiroshi Shiku PMCID: PMC64723 Complement activation in factor D-deficient mice Yuanyuan Xu, Minghe Ma, Gregory C. Ippolito, Harry W. Schroeder, Jr., Michael C. Carroll, and John E. Volanakis PMCID: PMC64724 Medical Sciences A high level of cyclooxygenase-2 inhibitor selectivity is
associated with a reduced interference of platelet cyclooxygenase-1
inactivation by aspirin Marc Ouellet, Denis Riendeau, and M. David Percival PMCID: PMC64725 Genetically engineered macrophages expressing IFN-γ restore
alveolar immune function in scid mice Min Wu, Shabbir Hussain, Ying-Hui He, Rajamouli Pasula, Patricia A. Smith, and William J. Martin, II PMCID: PMC64726 Two-step transcriptional amplification as a method for imaging
reporter gene expression using weak promoters M. Iyer, L. Wu, M. Carey, Y. Wang, A. Smallwood, and S. S. Gambhir PMCID: PMC64727 Chlorophyllin intervention reduces aflatoxin–DNA adducts in
individuals at high risk for liver cancer Patricia A. Egner, Jin-Bing Wang, Yuan-Rong Zhu, Bao-Chu Zhang, Yan Wu, Qi-Nan Zhang, Geng-Sun Qian, Shuang-Yuan Kuang, Stephen J. Gange, Lisa P. Jacobson, Kathy J. Helzlsouer, George S. Bailey, John D. Groopman, and Thomas W. Kensler PMCID: PMC64728 Microbiology Mutation frequency and biological cost of antibiotic resistance
in Helicobacter pylori Britta Björkholm, Maria Sjölund, Per G. Falk, Otto G. Berg, Lars Engstrand, and Dan I. Andersson PMCID: PMC64729 A quorum sensing-associated virulence gene of Pseudomonas
aeruginosa encodes a LysR-like transcription regulator with a
unique self-regulatory mechanism Hui Cao, Gomathi Krishnan, Boyan Goumnerov, John Tsongalis, Ronald Tompkins, and Laurence G. Rahme PMCID: PMC64730 A tumor host range selection procedure identifies
p150sal2 as a target of polyoma virus large T antigen Dawei Li, Ken Dower, Yupo Ma, Yu Tian, and Thomas L. Benjamin PMCID: PMC64731 Helicobacter pylori genetic diversity within the
gastric niche of a single human host Dawn A. Israel, Nina Salama, Uma Krishna, Ulrich M. Rieger, John C. Atherton, Stanley Falkow, and Richard M. Peek, Jr. PMCID: PMC64732 Activation of the Mason–Pfizer monkey virus protease within
immature capsids in vitro Scott D. Parker and Eric Hunter PMCID: PMC64733 The human salivary peptide histatin 5 exerts its antifungal
activity through the formation of reactive oxygen species Eva J. Helmerhorst, Robert F. Troxler, and Frank G. Oppenheim PMCID: PMC64734 Neurobiology Ligand-induced signal transduction within heterodimeric
GABAB receptor Marta Margeta-Mitrovic, Yuh Nung Jan, and Lily Yeh Jan PMCID: PMC64735 Function of GB1 and GB2 subunits in G protein coupling of
GABAB receptors Marta Margeta-Mitrovic, Yuh Nung Jan, and Lily Yeh Jan PMCID: PMC64736 Induction of multiple signaling loops by MuSK during
neuromuscular synapse formation Chris Moore, Marco Leu, Ulrich Müller, and Hans Rudolf Brenner PMCID: PMC64737 INAUGURAL ARTICLE by a Recently Elected Academy Member: Neurotrophins are key mediators of the myelination program in the
peripheral nervous system Jonah R. Chan, José Miguel Cosgaya, Yong Jian Wu, and Eric M. Shooter PMCID: PMC64738 Minocycline prevents nigrostriatal dopaminergic neurodegeneration
in the MPTP model of Parkinson's disease Yansheng Du, Zhizhong Ma, Suizhen Lin, Richard C. Dodel, Feng Gao, Kelly R. Bales, Lazarose C. Triarhou, Eyassu Chernet, Ken W. Perry, David L. G. Nelson, Susan Luecke, Lee A. Phebus, Frank P. Bymaster, and Steven M. Paul PMCID: PMC64739 Specific spatial learning deficits become severe with age in
β-amyloid precursor protein transgenic mice that harbor diffuse
β-amyloid deposits but do not form plaques Milla Koistinaho, Michael Ort, Jose M. Cimadevilla, Roman Vondrous, Barbara Cordell, Jari Koistinaho, Jan Bures, and Linda S. Higgins PMCID: PMC64740 Activation by GDNF of a transcriptional program repressing
neurite growth in dorsal root ganglia Sten Linnarsson, Åsa Mikaels, Christel Baudet, and Patrik Ernfors PMCID: PMC64741 Underediting of glutamate receptor GluR-B mRNA in
malignant gliomas Stefan Maas, Stephan Patt, Michael Schrey, and Alexander Rich PMCID: PMC64742 Candidate odorant receptors from the malaria vector mosquito
Anopheles gambiae and evidence of down-regulation in
response to blood feeding A. N. Fox, R. J. Pitts, H. M. Robertson, J. R. Carlson, and L. J. Zwiebel PMCID: PMC64743 Mechanisms underlying rapid experience-dependent plasticity in
the human visual cortex Babak Boroojerdi, Fortunato Battaglia, Wolf Muellbacher, and Leonardo G. Cohen PMCID: PMC64744 A caged Ab reveals an immediate/instructive effect of BDNF
during hippocampal synaptic potentiation Albrecht H. Kossel, Sidney B. Cambridge, Uta Wagner, and Tobias Bonhoeffer PMCID: PMC64745 PTP and LTP at a hippocampal mossy fiber-interneuron synapse Henrik Alle, Peter Jonas, and Jörg R. P. Geiger PMCID: PMC64746 Physiology The KCl cotransporter isoform KCC3 can play an important role in
cell growth regulation Meng-Ru Shen, Cheng-Yang Chou, Keng-Fu Hsu, Hsiao-Sheng Liu, Philip B. Dunham, Eli J. Holtzman, and J. Clive Ellory PMCID: PMC64747 Lipopolysaccharide-induced leptin release is neurally controlled C. A. Mastronardi, W. H. Yu, V. K. Srivastava, W. L. Dees, and S. M. McCann PMCID: PMC64748 Plant Biology Ricin A chain without its partner B chain is degraded after
retrotranslocation from the endoplasmic reticulum to the cytosol in
plant cells Alessandra Di Cola, Lorenzo Frigerio, J. Michael Lord, Aldo Ceriotti, and Lynne M. Roberts PMCID: PMC64749 A transcriptional roadmap to wood formation Magnus Hertzberg, Henrik Aspeborg, Jarmo Schrader, Anders Andersson, Rikard Erlandsson, Kristina Blomqvist, Rupali Bhalerao, Mathias Uhlén, Tuula T. Teeri, Joakim Lundeberg, Björn Sundberg, Peter Nilsson, and Göran Sandberg PMCID: PMC64750 Plastome-encoded bacterial ribulose-1,5-bisphosphate
carboxylase/oxygenase (RubisCO) supports photosynthesis and growth
in tobacco Spencer M. Whitney and T. John Andrews PMCID: PMC64751 Corrections Proc Natl Acad Sci U S A. 2001 December 4; 98(25): 14744. Published online 2001 November 20. PMCID: PMC64651 Corrects: Thomas C. Rich, et al. A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell. Proc Natl Acad Sci U S A. 2001 November 6; 98(23): 13049–13054. Proc Natl Acad Sci U S A. 2001 December 4; 98(25): 14744. Published online 2001 November 27. PMCID: PMC64652 Corrects: Fang Yu, et al. HIF-1α binding to VHL is regulated by stimulus-sensitive
proline hydroxylation. Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9630–9635. Proc Natl Acad Sci U S A. 2001 December 4; 98(25): 14744. Published online 2001 November 27. PMCID: PMC64653 Corrects: Anny Fortin, et al. Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice. Proc Natl Acad Sci U S A. 2001 September 11; 98(19): 10793–10798. |
