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Volume 101(40);  October 5, 2004
Commentary
Reverse transcriptase at bacterial telomeres
Neal F. Lue and Sulin Jiang
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14307–14308. Published online 2004 September 28. doi: 10.1073/pnas.0406018101.
PMCID: PMC521969
Perspective
Exercises in prognostication: Crystal structures and protein folding
Jack D. Dunitz and Harold A. Scheraga
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14309–14311. Published online 2004 September 27. doi: 10.1073/pnas.0405744101.
PMCID: PMC521964
Biographies
Biography of Erin K. O'Shea
Melissa Marino
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14312–14314. Published online 2004 September 28. doi: 10.1073/pnas.0406675101.
PMCID: PMC521978
Biography of Vernon M. Ingram
Tinsley H. Davis
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14323–14325. Published online 2004 September 28. doi: 10.1073/pnas.0406677101.
PMCID: PMC521979
Physical Sciences
Applied Mathematics
Entropy of dialogues creates coherent structures in e-mail traffic
Jean-Pierre Eckmann, Elisha Moses, and Danilo Sergi
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14333–14337. Published online 2004 September 24. doi: 10.1073/pnas.0405728101.
PMCID: PMC521963
Chemistry
Relationship of Leffler (Brønsted) α values and protein folding Φ values to position of transition-state structures on reaction coordinates
Alan R. Fersht
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14338–14342. Published online 2004 September 21. doi: 10.1073/pnas.0406091101.
PMCID: PMC521971
Probing conformational dynamics in single donor-acceptor synthetic molecules by means of photoinduced reversible electron transfer
Mircea Cotlet, Sadahiro Masuo, Guobin Luo, Johan Hofkens, Mark Van der Auweraer, Jan Verhoeven, Klaus Müllen, Xiaoliang Sunney Xie, and Frans De Schryver
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14343–14348. Published online 2004 September 23. doi: 10.1073/pnas.0406119101.
PMCID: PMC521947
Bulk-solvent and hydration-shell fluctuations, similar to α- and β-fluctuations in glasses, control protein motions and functions
P. W. Fenimore, Hans Frauenfelder, B. H. McMahon, and R. D. Young
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14408–14413. Published online 2004 September 24. doi: 10.1073/pnas.0405573101.
PMCID: PMC521939
Chemistry
Measuring single-molecule nucleic acid dynamics in solution by two-color filtered ratiometric fluorescence correlation spectroscopy
Haitao Li, Xiaojun Ren, Liming Ying, Shankar Balasubramanian, and David Klenerman
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14425–14430. Published online 2004 September 27. doi: 10.1073/pnas.0404295101.
PMCID: PMC521954
Biological Sciences
Agricultural Sciences
Sequence composition and genome organization of maize
Joachim Messing, Arvind K. Bharti, Wojciech M. Karlowski, Heidrun Gundlach, Hye Ran Kim, Yeisoo Yu, Fusheng Wei, Galina Fuks, Carol A. Soderlund, Klaus F. X. Mayer, and Rod A. Wing
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14349–14354. Published online 2004 September 23. doi: 10.1073/pnas.0406163101.
PMCID: PMC521949
Applied Biological Sciences
Responsive transporter genes within the murine intestinal-pancreatic axis form a basis of zinc homeostasis
Juan P. Liuzzi, Jeffrey A. Bobo, Louis A. Lichten, Don A. Samuelson, and Robert J. Cousins
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14355–14360. Published online 2004 September 20. doi: 10.1073/pnas.0406216101.
PMCID: PMC521973
Biochemistry
From the Cover:
Reverse transcriptase activity innate to DNA polymerase I and DNA topoisomerase I proteins of Streptomyces telomere complex
Kai Bao and Stanley N. Cohen
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14361–14366. Published online 2004 September 7. doi: 10.1073/pnas.0404386101.
PMCID: PMC521936
A poxvirus protein forms a complex with left-handed Z-DNA: Crystal structure of a Yatapoxvirus Zα bound to DNA
Sung Chul Ha, Neratur K. Lokanath, Dong Van Quyen, Chun Ai Wu, Ky Lowenhaupt, Alexander Rich, Yang-Gyun Kim, and Kyeong Kyu Kim
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14367–14372. Published online 2004 September 24. doi: 10.1073/pnas.0405586101.
PMCID: PMC521960
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins
Jing Song, Linda K. Durrin, Thomas A. Wilkinson, Theodore G. Krontiris, and Yuan Chen
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14373–14378. Published online 2004 September 23. doi: 10.1073/pnas.0403498101.
PMCID: PMC521952
Molecular dynamics studies of ground state and intermediate of the hyperthermophilic indole-3-glycerol phosphate synthase
Devleena Mazumder-Shivakumar and Thomas C. Bruice
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14379–14384. Published online 2004 September 27. doi: 10.1073/pnas.0406002101.
PMCID: PMC521968
Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity
Tim A. Rand, Krzysztof Ginalski, Nick V. Grishin, and Xiaodong Wang
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14385–14389. Published online 2004 September 27. doi: 10.1073/pnas.0405913101.
PMCID: PMC521941
Prohaptoglobin is proteolytically cleaved in the endoplasmic reticulum by the complement C1r-like protein
Krzysztof B. Wicher and Erik Fries
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14390–14395. Published online 2004 September 22. doi: 10.1073/pnas.0405692101.
PMCID: PMC521962
Long-range intramolecular signaling in a tRNA synthetase complex revealed by pre-steady-state kinetics
Nathan T. Uter and John J. Perona
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14396–14401. Published online 2004 September 27. doi: 10.1073/pnas.0404017101.
PMCID: PMC521953
Biophysics
Relationship of Leffler (Brønsted) α values and protein folding Φ values to position of transition-state structures on reaction coordinates
Alan R. Fersht
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14338–14342. Published online 2004 September 21. doi: 10.1073/pnas.0406091101.
PMCID: PMC521971
Different relaxations in myoglobin after photolysis
Matteo Levantino, Antonio Cupane, László Zimányi, and Pál Ormos
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14402–14407. Published online 2004 September 22. doi: 10.1073/pnas.0406062101.
PMCID: PMC521970
Bulk-solvent and hydration-shell fluctuations, similar to α- and β-fluctuations in glasses, control protein motions and functions
P. W. Fenimore, Hans Frauenfelder, B. H. McMahon, and R. D. Young
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14408–14413. Published online 2004 September 24. doi: 10.1073/pnas.0405573101.
PMCID: PMC521939
Biophysics
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels
Cristiano Viappiani, Stefano Bettati, Stefano Bruno, Luca Ronda, Stefania Abbruzzetti, Andrea Mozzarelli, and William A. Eaton
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14414–14419. Published online 2004 September 22. doi: 10.1073/pnas.0405987101.
PMCID: PMC521967
The formation of spherulites by amyloid fibrils of bovine insulin
Mark R. H. Krebs, Cait E. MacPhee, Aline F. Miller, Iain E. Dunlop, Christopher M. Dobson, and Athene M. Donald
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14420–14424. Published online 2004 September 20. doi: 10.1073/pnas.0405933101.
PMCID: PMC521966
Measuring single-molecule nucleic acid dynamics in solution by two-color filtered ratiometric fluorescence correlation spectroscopy
Haitao Li, Xiaojun Ren, Liming Ying, Shankar Balasubramanian, and David Klenerman
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14425–14430. Published online 2004 September 27. doi: 10.1073/pnas.0404295101.
PMCID: PMC521954
From the Cover:
Systematic investigation of protein phase behavior with a microfluidic formulator
Carl L. Hansen, Morten O. A. Sommer, and Stephen R. Quake
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14431–14436. Published online 2004 September 27. doi: 10.1073/pnas.0405847101.
PMCID: PMC521965
Phospholamban structural dynamics in lipid bilayers probed by a spin label rigidly coupled to the peptide backbone
Christine B. Karim, Tara L. Kirby, Zhiwen Zhang, Yuri Nesmelov, and David D. Thomas
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14437–14442. Published online 2004 September 24. doi: 10.1073/pnas.0402801101.
PMCID: PMC521948
Cell Biology
Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression
Rosa M. Marion, Aviv Regev, Eran Segal, Yoseph Barash, Daphne Koller, Nir Friedman, and Erin K. O'Shea
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14315–14322. Published online 2004 September 7. doi: 10.1073/pnas.0405353101.
PMCID: PMC521938
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation
Yiling Hong and Peter J. Stambrook
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14443–14448. Published online 2004 September 27. doi: 10.1073/pnas.0401346101.
PMCID: PMC521944
Developmental Biology
Foxa2 is required for transition to air breathing at birth
Huajing Wan, Yan Xu, Machiko Ikegami, Mildred T. Stahlman, Klaus H. Kaestner, Siew-Lan Ang, and Jeffrey A. Whitsett
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14449–14454. Published online 2004 September 27. doi: 10.1073/pnas.0404424101.
PMCID: PMC521955
Evolution
From the Cover:
Meager genetic variability of the human malaria agent Plasmodium vivax
M. C. Leclerc, P. Durand, C. Gauthier, S. Patot, N. Billotte, M. Menegon, C. Severini, F. J. Ayala, and F. Renaud
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14455–14460. Published online 2004 August 24. doi: 10.1073/pnas.0405186101.
PMCID: PMC521958
Immunology
A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation
Sumito Ogawa, Jean Lozach, Kristen Jepsen, Dominique Sawka-Verhelle, Valentina Perissi, Roman Sasik, David W. Rose, Randall S. Johnson, Michael G. Rosenfeld, and Christopher K. Glass
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14461–14466. Published online 2004 September 27. doi: 10.1073/pnas.0405786101.
PMCID: PMC521940
IFN-γ enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation
Mitsutoshi Matsuo, Yasuhiro Nagata, Eiichi Sato, Djordje Atanackovic, Danila Valmori, Yao-Tseng Chen, Gerd Ritter, Ira Mellman, Lloyd J. Old, and Sacha Gnjatic
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14467–14472. Published online 2004 September 21. doi: 10.1073/pnas.0405947101.
PMCID: PMC521945
Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells
Helene C. Dujardin, Odile Burlen-Defranoux, Laurent Boucontet, Paulo Vieira, Ana Cumano, and Antonio Bandeira
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14473–14478. Published online 2004 September 27. doi: 10.1073/pnas.0403303101.
PMCID: PMC521951
Medical Sciences
PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder
Jing Chen, Daniel J. DeAngelo, Jeffery L. Kutok, Ifor R. Williams, Benjamin H. Lee, Martha Wadleigh, Nicole Duclos, Sarah Cohen, Jennifer Adelsperger, Rachel Okabe, Allison Coburn, Ilene Galinsky, Brian Huntly, Pamela S. Cohen, Thomas Meyer, Doriano Fabbro, Johannes Roesel, Lolita Banerji, James D. Griffin, Sheng Xiao, Jonathan A. Fletcher, Richard M. Stone, and D. Gary Gilliland
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14479–14484. Published online 2004 September 24. doi: 10.1073/pnas.0404438101.
PMCID: PMC521956
Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study
Sudha K. Iyengar, Barbara E. K. Klein, Ronald Klein, Gyungah Jun, James H. Schick, Christopher Millard, Rachel Liptak, Karlie Russo, Kristine E. Lee, and Robert C. Elston
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14485–14490. Published online 2004 September 27. doi: 10.1073/pnas.0400778101.
PMCID: PMC521942
Microbiology
Sword and shield: Linked group B streptococcal β-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense
George Y. Liu, Kelly S. Doran, Toby Lawrence, Nicole Turkson, Manuela Puliti, Luciana Tissi, and Victor Nizet
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14491–14496. Published online 2004 September 20. doi: 10.1073/pnas.0406143101.
PMCID: PMC521972
Evidence for conservation of architecture and physical properties of Omp85-like proteins throughout evolution
Neeraj K. Surana, Susan Grass, Gail G. Hardy, Huilin Li, David G. Thanassi, and Joseph W. St. Geme, III
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14497–14502. Published online 2004 September 20. doi: 10.1073/pnas.0404679101.
PMCID: PMC521957
Neuroscience
Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule
Barbara J. Blanchard, Albert Chen, Leslie M. Rozeboom, Kate A. Stafford, Peter Weigele, and Vernon M. Ingram
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14326–14332. Published online 2004 September 23. doi: 10.1073/pnas.0405941101.
PMCID: PMC521943
Molecular profiling reveals synaptic release machinery in Merkel cells
Henry Haeberle, Mika Fujiwara, Jody Chuang, Michael M. Medina, Mayuri V. Panditrao, Susanne Bechstedt, Jonathon Howard, and Ellen A. Lumpkin
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14503–14508. Published online 2004 September 24. doi: 10.1073/pnas.0406308101.
PMCID: PMC521975
Distinct ontogenic and regional expressions of newly identified Cajal-Retzius cell-specific genes during neocorticogenesis
Hiroshi Yamazaki, Mariko Sekiguchi, Masako Takamatsu, Yasuto Tanabe, and Shigetada Nakanishi
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14509–14514. Published online 2004 September 27. doi: 10.1073/pnas.0406295101.
PMCID: PMC521974
Spatial memory, recognition memory, and the hippocampus
Nicola J. Broadbent, Larry R. Squire, and Robert E. Clark
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14515–14520. Published online 2004 September 27. doi: 10.1073/pnas.0406344101.
PMCID: PMC521976
Visual expertise with nonface objects leads to competition with the early perceptual processing of faces in the human occipitotemporal cortex
Bruno Rossion, Chun-Chia Kung, and Michael J. Tarr
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14521–14526. Published online 2004 September 24. doi: 10.1073/pnas.0405613101.
PMCID: PMC521961
Pharmacology
LEAPT: Lectin-directed enzyme-activated prodrug therapy
Mark A. Robinson, Stuart T. Charlton, Philippe Garnier, Xiang-tao Wang, Stanley S. Davis, Alan C. Perkins, Malcolm Frier, Ruth Duncan, Tony J. Savage, David A. Wyatt, Susan A. Watson, and Benjamin G. Davis
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14527–14532. Published online 2004 September 24. doi: 10.1073/pnas.0303574101.
PMCID: PMC521935
Plant Biology
From the Cover:
Evidence for landscape-level, pollen-mediated gene flow from genetically modified creeping bentgrass with CP4 EPSPS as a marker
Lidia S. Watrud, E. Henry Lee, Anne Fairbrother, Connie Burdick, Jay R. Reichman, Mike Bollman, Marjorie Storm, George King, and Peter K. Van de Water
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14533–14538. Published online 2004 September 24. doi: 10.1073/pnas.0405154101.
PMCID: PMC521937
Arabidopsis C-terminal domain phosphatase-like 1 and 2 are essential Ser-5-specific C-terminal domain phosphatases
Hisashi Koiwa, Stéphane Hausmann, Woo Young Bang, Akihiro Ueda, Naoko Kondo, Akihiro Hiraguri, Toshiyuki Fukuhara, Jeong Dong Bahk, Dae-Jin Yun, Ray A. Bressan, Paul M. Hasegawa, and Stewart Shuman
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14539–14544. Published online 2004 September 23. doi: 10.1073/pnas.0403174101.
PMCID: PMC521950
A specific form of thioredoxin h occurs in plant mitochondria and regulates the alternative oxidase
Eric Gelhaye, Nicolas Rouhier, Joelle Gérard, Yves Jolivet, José Gualberto, Nicolas Navrot, Per-Ingvard Ohlsson, Gunnar Wingsle, Masakazu Hirasawa, David B. Knaff, Hongmei Wang, Pierre Dizengremel, Yves Meyer, and Jean-Pierre Jacquot
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14545–14550. Published online 2004 September 22. doi: 10.1073/pnas.0405282101.
PMCID: PMC521959
Social Sciences
Social Sciences
Terror attacks influence driving behavior in Israel
Guy Stecklov and Joshua R. Goldstein
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14551–14556. Published online 2004 September 24. doi: 10.1073/pnas.0402483101.
PMCID: PMC521946
Correction
Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14557. Published online 2004 September 20. doi: 10.1073/pnas.0406534101.
PMCID: PMC521977
Corrects: Aymeric de Parseval, et al. Feline immunodeficiency virus targets activated CD4+ T cells by using CD134 as a binding receptor. Proc Natl Acad Sci U S A. 2004 August 31; 101(35): 13044–13049.
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