| | This journal provides immediate access to some articles. Letter The epidemiology of AIDS in Haiti refutes the claims of Gilbert et al. Jean William Pape, Paul Farmer, Serena Koenig, Daniel Fitzgerald, Peter Wright, and Warren Johnson PMCID: PMC2268778 This Week in PNAS Proc Natl Acad Sci U S A. 2008 March 11; 105(10): 3659–3660. doi: 10.1073/iti1008105.PMCID: PMC2268807 Commentary Does antisense make sense of AID targeting? Sergio Roa, Fei Li Kuang, and Matthew D. Scharff PMCID: PMC2268770 Physical Sciences Applied Physical Sciences From the Cover:
Microfluidics of cytoplasmic streaming and its implications for intracellular transport Raymond E. Goldstein, Idan Tuval, and Jan-Willem van de Meent PMCID: PMC2268784 A 16-bit parallel processing in a molecular assembly Anirban Bandyopadhyay and Somobrata Acharya PMCID: PMC2268776 Vacancy-mediated dehydrogenation of sodium alanate Hakan Gunaydin, Kendall N. Houk, and Vidvuds Ozoliņš PMCID: PMC2268810 Chemistry A nanostructure-initiator mass spectrometry-based enzyme activity assay Trent R. Northen, Jinq-Chyi Lee, Linh Hoang, Jason Raymond, Der-Ren Hwang, Steven M. Yannone, Chi-Huey Wong, and Gary Siuzdak PMCID: PMC2268803 DNA binding shifts the redox potential of the transcription factor SoxR Alon A. Gorodetsky, Lars E. P. Dietrich, Paul E. Lee, Bruce Demple, Dianne K. Newman, and Jacqueline K. Barton PMCID: PMC2268809 Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN Sheng-Kai Wang, Pi-Hui Liang, Rena D. Astronomo, Tsui-Ling Hsu, Shie-Liang Hsieh, Dennis R. Burton, and Chi-Huey Wong PMCID: PMC2268808 From the Cover:
Layered metal sulfides: Exceptionally selective agents for radioactive strontium removal Manolis J. Manos, Nan Ding, and Mercouri G. Kanatzidis PMCID: PMC2268822 Molecular asymmetry in extraterrestrial chemistry: Insights from a pristine meteorite Sandra Pizzarello, Yongsong Huang, and Marcelo R. Alexandre PMCID: PMC2268819 Engineering Simultaneous in vivo positron emission tomography and magnetic resonance imaging Ciprian Catana, Daniel Procissi, Yibao Wu, Martin S. Judenhofer, Jinyi Qi, Bernd J. Pichler, Russell E. Jacobs, and Simon R. Cherry PMCID: PMC2268792 Micro- and nanoparticles self-assembly for virtually defect-free, adjustable monolayers N. Aubry, P. Singh, M. Janjua, and S. Nudurupati PMCID: PMC2268815 Biological Sciences Anthropology Heritability of cooperative behavior in the trust game David Cesarini, Christopher T. Dawes, James H. Fowler, Magnus Johannesson, Paul Lichtenstein, and Björn Wallace PMCID: PMC2268795 Applied Biological Sciences Cost-effective production of a vaginal protein microbicide to prevent HIV transmission Koreen Ramessar, Thomas Rademacher, Markus Sack, Johannes Stadlmann, Dimitris Platis, Gabriela Stiegler, Nikos Labrou, Fritz Altmann, Julian Ma, Eva Stöger, Teresa Capell, and Paul Christou PMCID: PMC2268773 In vitro self-assembly of tailorable nanotubes from a simple protein building block Edward R. Ballister, Angela H. Lai, Ronald N. Zuckermann, Yifan Cheng, and Joseph D. Mougous PMCID: PMC2268831 Biochemistry A nanostructure-initiator mass spectrometry-based enzyme activity assay Trent R. Northen, Jinq-Chyi Lee, Linh Hoang, Jason Raymond, Der-Ren Hwang, Steven M. Yannone, Chi-Huey Wong, and Gary Siuzdak PMCID: PMC2268803 DNA binding shifts the redox potential of the transcription factor SoxR Alon A. Gorodetsky, Lars E. P. Dietrich, Paul E. Lee, Bruce Demple, Dianne K. Newman, and Jacqueline K. Barton PMCID: PMC2268809 Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN Sheng-Kai Wang, Pi-Hui Liang, Rena D. Astronomo, Tsui-Ling Hsu, Shie-Liang Hsieh, Dennis R. Burton, and Chi-Huey Wong PMCID: PMC2268808 A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies Gary Frey, Hanqin Peng, Sophia Rits-Volloch, Marco Morelli, Yifan Cheng, and Bing Chen PMCID: PMC2268799 The thermodynamic H+/ATP ratios of the H+-ATPsynthases from chloroplasts and Escherichia coli Stefan Steigmiller, Paola Turina, and Peter Gräber PMCID: PMC2268821 Analyses of Mlc–IIBGlc interaction and a plausible molecular mechanism of Mlc inactivation by membrane sequestration Tae-Wook Nam, Ha Il Jung, Young Jun An, Young-Ha Park, Sang Hee Lee, Yeong-Jae Seok, and Sun-Shin Cha PMCID: PMC2268834 Cleavage mechanism of human Mus81–Eme1 acting on Holliday-junction structures Ewan R. Taylor and Clare H. McGowan PMCID: PMC2268786 Real-time electron transfer in respiratory complex I Marina L. Verkhovskaya, Nikolai Belevich, Liliya Euro, Mårten Wikström, and Michael I. Verkhovsky PMCID: PMC2268814 Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination Ildiko Unk, Ildikó Hajdú, Károly Fátyol, Jerard Hurwitz, Jung-Hoon Yoon, Louise Prakash, Satya Prakash, and Lajos Haracska PMCID: PMC2268824 Opening and closing of the periplasmic gate in lactose permease Yonggang Zhou, Lan Guan, J. Alfredo Freites, and H. Ronald Kaback PMCID: PMC2268789 Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice Natalia Gustavsson, Ye Lao, Anton Maximov, Jen-Chieh Chuang, Elena Kostromina, Joyce J. Repa, Cai Li, George K. Radda, Thomas C. Südhof, and Weiping Han PMCID: PMC2268794 Biophysics From the Cover:
Microfluidics of cytoplasmic streaming and its implications for intracellular transport Raymond E. Goldstein, Idan Tuval, and Jan-Willem van de Meent PMCID: PMC2268784 Structural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat protein Christian Löw, Ulrich Weininger, Piotr Neumann, Mirjam Klepsch, Hauke Lilie, Milton T. Stubbs, and Jochen Balbach PMCID: PMC2268769 Cell Biology TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression Youhna M. Ayala, Tom Misteli, and Francisco E. Baralle PMCID: PMC2268791 Developmental Biology A Caenorhabditis elegans model for epithelial–neuronal transdifferentiation Sophie Jarriault, Yannick Schwab, and Iva Greenwald PMCID: PMC2268801 Ecology Rapid evolution of seed dispersal in an urban environment in the weed Crepis sancta P.-O. Cheptou, O. Carrue, S. Rouifed, and A. Cantarel PMCID: PMC2268839 Introduced rats indirectly change marine rocky intertidal communities from algae- to invertebrate-dominated Carolyn M. Kurle, Donald A. Croll, and Bernie R. Tershy PMCID: PMC2268820 Environmental Sciences From the Cover:
Microbial community gene expression in ocean surface waters Jorge Frias-Lopez, Yanmei Shi, Gene W. Tyson, Maureen L. Coleman, Stephan C. Schuster, Sallie W. Chisholm, and Edward F. DeLong PMCID: PMC2268829 Mushroom fruiting and climate change Håvard Kauserud, Leif Christian Stige, Jon Olav Vik, Rune H. Økland, Klaus Høiland, and Nils Chr. Stenseth PMCID: PMC2268836 Evolution The oldest North American primate and mammalian biogeography during the Paleocene–Eocene Thermal Maximum K. Christopher Beard PMCID: PMC2268774 Elephant shark sequence reveals unique insights into the evolutionary history of vertebrate genes: A comparative analysis of the protocadherin cluster Wei-Ping Yu, Vikneswari Rajasegaran, Kenneth Yew, Wai-lin Loh, Boon-Hui Tay, Chris T. Amemiya, Sydney Brenner, and Byrappa Venkatesh PMCID: PMC2268768 Immunology Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7 Arnold H. Bakker, Rieuwert Hoppes, Carsten Linnemann, Mireille Toebes, Boris Rodenko, Celia R. Berkers, Sine Reker Hadrup, Wim J. E. van Esch, Mirjam H. M. Heemskerk, Huib Ovaa, and Ton N. M. Schumacher PMCID: PMC2268811 Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers Gijsbert M. Grotenbreg, Nadia R. Roan, Eduardo Guillen, Rob Meijers, Jia-huai Wang, George W. Bell, Michael N. Starnbach, and Hidde L. Ploegh PMCID: PMC2268777 Identification of phosphatidylinositol 4-kinase type II β as HLA class II-restricted target in graft versus leukemia reactivity Marieke Griffioen, Edith D. van der Meijden, Elisabeth H. Slager, M. Willy Honders, Caroline E. Rutten, Simone A. P. van Luxemburg-Heijs, Peter A. von dem Borne, Johannes J. van Rood, Roel Willemze, and J. H. Frederik Falkenburg PMCID: PMC2268788 From the Cover:
Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions Thomas Perlot, Gang Li, and Frederick W. Alt PMCID: PMC2268805 Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen Daniel E. Speiser, Petra Baumgaertner, Verena Voelter, Estelle Devevre, Catherine Barbey, Nathalie Rufer, and Pedro Romero PMCID: PMC2268830 T cell expression of MyD88 is required for resistance to Toxoplasma gondii David F. LaRosa, Jason S. Stumhofer, Andrew E. Gelman, Adeeb H. Rahman, Devon K. Taylor, Christopher A. Hunter, and Laurence A. Turka PMCID: PMC2268781 Editing and escape from editing in anti-DNA B cells Salar N. Khan, Esther J. Witsch, Noah G. Goodman, Anil K. Panigrahi, Ching Chen, Yufei Jiang, Amy M. Cline, Jan Erikson, Martin Weigert, Eline T. Luning Prak, and Marko Radic PMCID: PMC2268806 HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype Simona Fiorentini, Elena Riboldi, Fabio Facchetti, Manuela Avolio, Marco Fabbri, Giorgio Tosti, Pablo D. Becker, Carlos A. Guzman, Silvano Sozzani, and Arnaldo Caruso PMCID: PMC2268771 Nucleoprotein structure of the CD4 locus: Implications for the mechanisms underlying CD4 regulation during T cell development Ming Yu, Mimi Wan, Jianmin Zhang, Jie Wu, Rohini Khatri, and Tian Chi PMCID: PMC2268827 Medical Sciences Simultaneous in vivo positron emission tomography and magnetic resonance imaging Ciprian Catana, Daniel Procissi, Yibao Wu, Martin S. Judenhofer, Jinyi Qi, Bernd J. Pichler, Russell E. Jacobs, and Simon R. Cherry PMCID: PMC2268792 Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy Sarah Palmer, Frank Maldarelli, Ann Wiegand, Barry Bernstein, George J. Hanna, Scott C. Brun, Dale J. Kempf, John W. Mellors, John M. Coffin, and Martin S. King PMCID: PMC2268833 Kuru prions and sporadic Creutzfeldt–Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice Jonathan D. F. Wadsworth, Susan Joiner, Jacqueline M. Linehan, Melanie Desbruslais, Katie Fox, Sharon Cooper, Sabrina Cronier, Emmanuel A. Asante, Simon Mead, Sebastian Brandner, Andrew F. Hill, and John Collinge PMCID: PMC2268835 The organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis Anuradha Rao, Jamie Haywood, Ann L. Craddock, Martin G. Belinsky, Gary D. Kruh, and Paul A. Dawson PMCID: PMC2268840 RelB is the NF-κB subunit downstream of NIK responsible for osteoclast differentiation Sergio Vaira, Trevor Johnson, Angela C. Hirbe, Muhammad Alhawagri, Imani Anwisye, Benedicte Sammut, Julie O'Neal, Wei Zou, Katherine N. Weilbaecher, Roberta Faccio, and Deborah Veis Novack PMCID: PMC2268780 Suppression of non-small cell lung tumor development by the let-7 microRNA family Madhu S. Kumar, Stefan J. Erkeland, Ryan E. Pester, Cindy Y. Chen, Margaret S. Ebert, Phillip A. Sharp, and Tyler Jacks PMCID: PMC2268826 In vivo correction of a Menkes disease model using antisense oligonucleotides Erik C. Madsen, Paul A. Morcos, Bryce A. Mendelsohn, and Jonathan D. Gitlin PMCID: PMC2268804 Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population Jinyan Wang, Hideyuki Takeuchi, Yoshifumi Sonobe, Shijie Jin, Tetsuya Mizuno, Shin Miyakawa, Masatoshi Fujiwara, Yoshikazu Nakamura, Takuma Kato, Hisako Muramatsu, Takashi Muramatsu, and Akio Suzumura PMCID: PMC2268842 Txnip balances metabolic and growth signaling via PTEN disulfide reduction Simon T. Y. Hui, Allen M. Andres, Amber K. Miller, Nathanael J. Spann, Douglas W. Potter, Noah M. Post, Amelia Z. Chen, Sowbarnika Sachithanantham, Dae Young Jung, Jason K. Kim, and Roger A. Davis PMCID: PMC2268825 Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad Shun-Fu Chang, Cheng Allen Chang, Ding-Yu Lee, Pei-Ling Lee, Yu-Ming Yeh, Chiuan-Ren Yeh, Cheng-Kung Cheng, Shu Chien, and Jeng-Jiann Chiu PMCID: PMC2268796 Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition Sanjeev Shangary, Dongguang Qin, Donna McEachern, Meilan Liu, Rebecca S. Miller, Su Qiu, Zaneta Nikolovska-Coleska, Ke Ding, Guoping Wang, Jianyong Chen, Denzil Bernard, Jian Zhang, Yipin Lu, Qingyang Gu, Rajal B. Shah, Kenneth J. Pienta, Xiaolan Ling, Sanmao Kang, Ming Guo, Yi Sun, Dajun Yang, and Shaomeng Wang PMCID: PMC2268798 Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation Zhengrong Hao, Yan Huang, Jake Cleman, Ion S. Jovin, Wylie W. Vale, Tracy L. Bale, and Frank J. Giordano PMCID: PMC2268793 Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin Ramiro Garzon, Michela Garofalo, Maria Paola Martelli, Roger Briesewitz, Lisheng Wang, Cecilia Fernandez-Cymering, Stefano Volinia, Chang-Gong Liu, Susanne Schnittger, Torsten Haferlach, Arcangelo Liso, Daniela Diverio, Marco Mancini, Giovanna Meloni, Robin Foa, Massimo F. Martelli, Cristina Mecucci, Carlo M. Croce, and Brunangelo Falini PMCID: PMC2268779 Microbiology From the Cover:
Regulation of surface architecture by symbiotic bacteria mediates host colonization Cui Hua Liu, S. Melanie Lee, Jordan M. VanLare, Dennis L. Kasper, and Sarkis K. Mazmanian PMCID: PMC2268772 Antibiotic-resistant soil bacteria in transgenic plant fields Sandrine Demanèche, Hervé Sanguin, John Poté, Elisabeth Navarro, Dominique Bernillon, Patrick Mavingui, Walter Wildi, Timothy M. Vogel, and Pascal Simonet PMCID: PMC2268783 Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure Christian Hoffmann, Andrew Leis, Michael Niederweis, Jürgen M. Plitzko, and Harald Engelhardt PMCID: PMC2268800 Shewanella secretes flavins that mediate extracellular electron transfer Enrico Marsili, Daniel B. Baron, Indraneel D. Shikhare, Dan Coursolle, Jeffrey A. Gralnick, and Daniel R. Bond PMCID: PMC2268775 ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity Atsushi Okumura, Paula M. Pitha, and Ronald N. Harty PMCID: PMC2268823 Leishmania requires Rab7-mediated degradation of endocytosed hemoglobin for their growth Nitin Patel, Sudha B. Singh, Sandip K. Basu, and Amitabha Mukhopadhyay PMCID: PMC2268841 Neuroscience Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis Anton Maximov, Ye Lao, Hongmei Li, Xiaocheng Chen, Josep Rizo, Jakob B. Sørensen, and Thomas C. Südhof PMCID: PMC2268828 Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice Natalia Gustavsson, Ye Lao, Anton Maximov, Jen-Chieh Chuang, Elena Kostromina, Joyce J. Repa, Cai Li, George K. Radda, Thomas C. Südhof, and Weiping Han PMCID: PMC2268794 Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells Jean-Sébastien Schonn, Anton Maximov, Ye Lao, Thomas C. Südhof, and Jakob B. Sørensen PMCID: PMC2268838 Language affects patterns of brain activation associated with perceptual decision Li Hai Tan, Alice H. D. Chan, Paul Kay, Pek-Lan Khong, Lawrance K. C. Yip, and Kang-Kwong Luke PMCID: PMC2268832 Internal body state influences topographical plasticity of sensory representations in the rat gustatory cortex Riccardo Accolla and Alan Carleton PMCID: PMC2268816 Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene Kwon-Yul Ryu, Jacob C. Garza, Xin-Yun Lu, Gregory S. Barsh, and Ron R. Kopito PMCID: PMC2268782 Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria Christine Vande Velde, Timothy M. Miller, Neil R. Cashman, and Don W. Cleveland PMCID: PMC2268797 The maturing architecture of the brain's default network Damien A. Fair, Alexander L. Cohen, Nico U. F. Dosenbach, Jessica A. Church, Francis M. Miezin, Deanna M. Barch, Marcus E. Raichle, Steven E. Petersen, and Bradley L. Schlaggar PMCID: PMC2268790 Physiology Gating-associated conformational changes in the mechanosensitive channel MscL Kenjiro Yoshimura, Jiro Usukura, and Masahiro Sokabe PMCID: PMC2268802 The RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels Shangwei Hou, Rong Xu, Stefan H. Heinemann, and Toshinori Hoshi PMCID: PMC2268785 Plant Biology A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes Dipanwita Basu, Jie Le, Taya Zakharova, Eileen L. Mallery, and Daniel B. Szymanski PMCID: PMC2268813 In vivo hyperspectral confocal fluorescence imaging to determine pigment localization and distribution in cyanobacterial cells Wim F. J. Vermaas, Jerilyn A. Timlin, Howland D. T. Jones, Michael B. Sinclair, Linda T. Nieman, Sawsan W. Hamad, David K. Melgaard, and David M. Haaland PMCID: PMC2268818 Thioredoxin-mediated reversible dissociation of a stromal multiprotein complex in response to changes in light availability Thomas P. Howard, Metodi Metodiev, Julie C. Lloyd, and Christine A. Raines PMCID: PMC2268787 Barley grain with adhering hulls is controlled by an ERF family transcription factor gene regulating a lipid biosynthesis pathway Shin Taketa, Satoko Amano, Yasuhiro Tsujino, Tomohiko Sato, Daisuke Saisho, Katsuyuki Kakeda, Mika Nomura, Toshisada Suzuki, Takashi Matsumoto, Kazuhiro Sato, Hiroyuki Kanamori, Shinji Kawasaki, and Kazuyoshi Takeda PMCID: PMC2268812 Psychology Broad bandwidth of perceptual learning in the visual system of adults with anisometropic amblyopia Chang-Bing Huang, Yifeng Zhou, and Zhong-Lin Lu PMCID: PMC2268837 Social Sciences Anthropology Domestication of the donkey: Timing, processes, and indicators Stine Rossel, Fiona Marshall, Joris Peters, Tom Pilgram, Matthew D. Adams, and David O'Connor PMCID: PMC2268817 Economic Sciences Heritability of cooperative behavior in the trust game David Cesarini, Christopher T. Dawes, James H. Fowler, Magnus Johannesson, Paul Lichtenstein, and Björn Wallace PMCID: PMC2268795 Psychology Language affects patterns of brain activation associated with perceptual decision Li Hai Tan, Alice H. D. Chan, Paul Kay, Pek-Lan Khong, Lawrance K. C. Yip, and Kang-Kwong Luke PMCID: PMC2268832 |
