| | This journal provides immediate access to some articles. Inaugural Article Strategies for developing Green Super Rice Qifa Zhang PMCID: PMC2034246 This Week in PNAS Proc Natl Acad Sci U S A. 2007 October 16; 104(42): 16391–16392. doi: 10.1073/iti4207104.PMCID: PMC2034225 Editorial Introducing PNAS online letters to the editor Randy Schekman PMCID: PMC2034237 Commentaries Fish respond when the mercury rises Daniel R. Engstrom PMCID: PMC2034244 Has evolution primed humans to “beware the beast”? Arne Öhman PMCID: PMC2034250 The TCR binding site does move Wolfgang W. A. Schamel and Michael Reth PMCID: PMC2034258 Has hair cell loss MET its match? Matthew W. Kelley PMCID: PMC2034239 Physical Sciences Chemistry 3′-O-modified nucleotides as reversible terminators for pyrosequencing Jian Wu, Shenglong Zhang, Qinglin Meng, Huanyan Cao, Zengmin Li, Xiaoxu Li, Shundi Shi, Dae Hyun Kim, Lanrong Bi, Nicholas J. Turro, and Jingyue Ju PMCID: PMC2034218 Engineering From the Cover:
Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of α-helical and β-sheet protein domains Theodor Ackbarow, Xuefeng Chen, Sinan Keten, and Markus J. Buehler PMCID: PMC2034213 Geology East African megadroughts between 135 and 75 thousand years ago and bearing on early-modern human origins Christopher A. Scholz, Thomas C. Johnson, Andrew S. Cohen, John W. King, John A. Peck, Jonathan T. Overpeck, Michael R. Talbot, Erik T. Brown, Leonard Kalindekafe, Philip Y. O. Amoako, Robert P. Lyons, Timothy M. Shanahan, Isla S. Castañeda, Clifford W. Heil, Steven L. Forman, Lanny R. McHargue, Kristina R. Beuning, Jeanette Gomez, and James Pierson PMCID: PMC1964544 Ecological consequences of early Late Pleistocene megadroughts in tropical Africa Andrew S. Cohen, Jeffery R. Stone, Kristina R. M. Beuning, Lisa E. Park, Peter N. Reinthal, David Dettman, Christopher A. Scholz, Thomas C. Johnson, John W. King, Michael R. Talbot, Erik T. Brown, and Sarah J. Ivory PMCID: PMC2034256 Unusual lattice dynamics of vanadium under high pressure Wei Luo, Rajeev Ahuja, Yang Ding, and Ho-kwang Mao PMCID: PMC2034226 From the Cover:
Diffusion-controlled metabolism for long-term survival of single isolated microorganisms trapped within ice crystals Robert A. Rohde and P. Buford Price PMCID: PMC2034245 Physics Spontaneous knotting of an agitated string Dorian M. Raymer and Douglas E. Smith PMCID: PMC2034230 Statistics A gene regulatory network in mouse embryonic stem cells Qing Zhou, Hiram Chipperfield, Douglas A. Melton, and Wing Hung Wong PMCID: PMC2034259 Biological Sciences Agricultural Sciences Strategies for developing Green Super Rice Qifa Zhang PMCID: PMC2034246 Plant nuclear factor Y (NF-Y) B subunits confer drought tolerance and lead to improved corn yields on water-limited acres Donald E. Nelson, Peter P. Repetti, Tom R. Adams, Robert A. Creelman, Jingrui Wu, David C. Warner, Don C. Anstrom, Robert J. Bensen, Paolo P. Castiglioni, Meghan G. Donnarummo, Brendan S. Hinchey, Roderick W. Kumimoto, Don R. Maszle, Roger D. Canales, Katherine A. Krolikowski, Stanton B. Dotson, Neal Gutterson, Oliver J. Ratcliffe, and Jacqueline E. Heard PMCID: PMC2034233 Anthropology East African megadroughts between 135 and 75 thousand years ago and bearing on early-modern human origins Christopher A. Scholz, Thomas C. Johnson, Andrew S. Cohen, John W. King, John A. Peck, Jonathan T. Overpeck, Michael R. Talbot, Erik T. Brown, Leonard Kalindekafe, Philip Y. O. Amoako, Robert P. Lyons, Timothy M. Shanahan, Isla S. Castañeda, Clifford W. Heil, Steven L. Forman, Lanny R. McHargue, Kristina R. Beuning, Jeanette Gomez, and James Pierson PMCID: PMC1964544 Stable isotope and DNA evidence for ritual sequences in Inca child sacrifice Andrew S. Wilson, Timothy Taylor, Maria Constanza Ceruti, Jose Antonio Chavez, Johan Reinhard, Vaughan Grimes, Wolfram Meier-Augenstein, Larry Cartmell, Ben Stern, Michael P. Richards, Michael Worobey, Ian Barnes, and M. Thomas P. Gilbert PMCID: PMC2034262 Applied Biological Sciences 3′-O-modified nucleotides as reversible terminators for pyrosequencing Jian Wu, Shenglong Zhang, Qinglin Meng, Huanyan Cao, Zengmin Li, Xiaoxu Li, Shundi Shi, Dae Hyun Kim, Lanrong Bi, Nicholas J. Turro, and Jingyue Ju PMCID: PMC2034218 Variant estrogen receptor–c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation Lei Li, Koji Hisamoto, Kyung Hee Kim, M. Page Haynes, Philip M. Bauer, Archana Sanjay, Mark Collinge, Roland Baron, William C. Sessa, and Jeffrey R. Bender PMCID: PMC2034248 Biochemistry Structural basis for antiactivation in bacterial quorum sensing Guozhou Chen, Philip D. Jeffrey, Clay Fuqua, Yigong Shi, and Lingling Chen PMCID: PMC2034266 Continuous fat oxidation in acetyl–CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity Cheol Soo Choi, David B. Savage, Lutfi Abu-Elheiga, Zhen-Xiang Liu, Sheene Kim, Ameya Kulkarni, Alberto Distefano, Yu-Jin Hwang, Richard M. Reznick, Roberto Codella, Dongyan Zhang, Gary W. Cline, Salih J. Wakil, and Gerald I. Shulman PMCID: PMC2034222 Polyphosphate kinase 1, a conserved bacterial enzyme, in a eukaryote, Dictyostelium discoideum, with a role in cytokinesis Haiyu Zhang, María R. Gómez-García, Xiaobing Shi, Narayana N. Rao, and Arthur Kornberg PMCID: PMC2034253 A glycosyltransferase with a length-controlling activity as a mechanism to regulate the size of polysaccharides Andrés E. Ciocchini, L. Soledad Guidolin, Adriana C. Casabuono, Alicia S. Couto, Nora Iñón de Iannino, and Rodolfo A. Ugalde PMCID: PMC2034269 Cloning and characterization of the biosynthetic gene cluster for kutznerides Danica Galonić Fujimori, Siniša Hrvatin, Christopher S. Neumann, Matthias Strieker, Mohamed A. Marahiel, and Christopher T. Walsh PMCID: PMC2034236 Sugar binding induces an outward facing conformation of LacY Irina Smirnova, Vladimir Kasho, Jun-Yong Choe, Christian Altenbach, Wayne L. Hubbell, and H. Ronald Kaback PMCID: PMC2034228 Biophysics From the Cover:
Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of α-helical and β-sheet protein domains Theodor Ackbarow, Xuefeng Chen, Sinan Keten, and Markus J. Buehler PMCID: PMC2034213 Longitudinally propagating traveling waves of the mammalian tectorial membrane Roozbeh Ghaffari, Alexander J. Aranyosi, and Dennis M. Freeman PMCID: PMC2034249 Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy Shang-Te Danny Hsu, Paola Fucini, Lisa D. Cabrita, Hélène Launay, Christopher M. Dobson, and John Christodoulou PMCID: PMC2034214 Familial Alzheimer's disease mutations alter the stability of the amyloid β-protein monomer folding nucleus Marianne A. Grant, Noel D. Lazo, Aleksey Lomakin, Margaret M. Condron, Hiromi Arai, Ghiam Yamin, Alan C. Rigby, and David B. Teplow PMCID: PMC2034231 Phylogenomic analysis of the emergence of GC-rich transcription elements Patricia Khuu, Maurice Sandor, Jennifer DeYoung, and P. Shing Ho PMCID: PMC2034261 Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference Léa Desigaux, Matthieu Sainlos, Olivier Lambert, Raphael Chevre, Emilie Letrou-Bonneval, Jean-Pierre Vigneron, Pierre Lehn, Jean-Marie Lehn, and Bruno Pitard PMCID: PMC2034216 Transfer RNA in the hybrid P/E state: Correlating molecular dynamics simulations with cryo-EM data Wen Li and Joachim Frank PMCID: PMC2034235 Cell Biology Chromosome territory reorganization in a human disease with altered DNA methylation Maria R. Matarazzo, Shelagh Boyle, Maurizio D'Esposito, and Wendy A. Bickmore PMCID: PMC2034264 Increased survival of muscle stem cells lacking the MyoD gene after transplantation into regenerating skeletal muscle Atsushi Asakura, Hiroyuki Hirai, Boris Kablar, Shigeru Morita, Jeff Ishibashi, Bryan A. Piras, Amanda J. Christ, Mayank Verma, Karin A. Vineretsky, and Michael A. Rudnicki PMCID: PMC2034220 Developmental Biology A gene regulatory network in mouse embryonic stem cells Qing Zhou, Hiram Chipperfield, Douglas A. Melton, and Wing Hung Wong PMCID: PMC2034259 Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination Yuna Kim, Nathan Bingham, Ryohei Sekido, Keith L. Parker, Robin Lovell-Badge, and Blanche Capel PMCID: PMC2034251 Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A Judy Qiju Wu, David V. Hansen, Yanxiang Guo, Michael Zhuo Wang, Wanli Tang, Christopher D. Freel, Jeffrey J. Tung, Peter K. Jackson, and Sally Kornbluth PMCID: PMC2034268 Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation Xiaochun Long, Esther E. Creemers, Da-Zhi Wang, Eric N. Olson, and Joseph M. Miano PMCID: PMC2034223 Ecology Deep-water kelp refugia as potential hotspots of tropical marine diversity and productivity Michael H. Graham, Brian P. Kinlan, Louis D. Druehl, Lauren E. Garske, and Stuart Banks PMCID: PMC2034254 Aquatic organisms as amber inclusions and examples from a modern swamp forest Alexander R. Schmidt and David L. Dilcher PMCID: PMC2034260 Environmental Sciences Whole-ecosystem study shows rapid fish-mercury response to changes in mercury deposition Reed C. Harris, John W. M. Rudd, Marc Amyot, Christopher L. Babiarz, Ken G. Beaty, Paul J. Blanchfield, R. A. Bodaly, Brian A. Branfireun, Cynthia C. Gilmour, Jennifer A. Graydon, Andrew Heyes, Holger Hintelmann, James P. Hurley, Carol A. Kelly, David P. Krabbenhoft, Steve E. Lindberg, Robert P. Mason, Michael J. Paterson, Cheryl L. Podemski, Art Robinson, Ken A. Sandilands, George R. Southworth, Vincent L. St. Louis, and Michael T. Tate PMCID: PMC2034227 From the Cover:
Diffusion-controlled metabolism for long-term survival of single isolated microorganisms trapped within ice crystals Robert A. Rohde and P. Buford Price PMCID: PMC2034245 Evolution Ecological consequences of early Late Pleistocene megadroughts in tropical Africa Andrew S. Cohen, Jeffery R. Stone, Kristina R. M. Beuning, Lisa E. Park, Peter N. Reinthal, David Dettman, Christopher A. Scholz, Thomas C. Johnson, John W. King, Michael R. Talbot, Erik T. Brown, and Sarah J. Ivory PMCID: PMC2034256 Category-specific attention for animals reflects ancestral priorities, not expertise Joshua New, Leda Cosmides, and John Tooby PMCID: PMC2034212 From the Cover:
Quantitative genetic correlation between trait and preference supports a sexually selected sperm process Leigh W. Simmons and Janne S. Kotiaho PMCID: PMC2034270 Genetics Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z Shivkumar Venkatasubrahmanyam, William W. Hwang, Marc D. Meneghini, Amy Hin Yan Tong, and Hiten D. Madhani PMCID: PMC2034229 Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins Christian Beisel, Andreas Buness, Ian M. Roustan-Espinosa, Britta Koch, Sabine Schmitt, Stefan A. Haas, Marc Hild, Tomonori Katsuyama, and Renato Paro PMCID: PMC2001164 Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence René Gysin, Rudolf Kraftsik, Julie Sandell, Pierre Bovet, Céline Chappuis, Philippe Conus, Patricia Deppen, Martin Preisig, Viviane Ruiz, Pascal Steullet, Mirjana Tosic, Thomas Werge, Michel Cuénod, and Kim Q. Do PMCID: PMC2034265 A mouse model of conditional lipodystrophy Suyeon Kim, Li-Wen Huang, Kathy J. Snow, Vitaly Ablamunits, Muneer G. Hasham, Timothy H. Young, Angelique C. Paulk, Joel E. Richardson, Jason P. Affourtit, Tali Shalom-Barak, Carol J. Bult, and Yaacov Barak PMCID: PMC2034232 Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations Zhaohui Feng, Wenwei Hu, Angelika K. Teresky, Eva Hernando, Carlos Cordon-Cardo, and Arnold J. Levine PMCID: PMC2034252 Immunology Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor Dmitry M. Gakamsky, Erwin Lewitzki, Ernst Grell, Xavier Saulquin, Bernard Malissen, Felix Montero-Julian, Marc Bonneville, and Israel Pecht PMCID: PMC2034217 From the Cover:
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans Bart Ferwerda, Matthew B. B. McCall, Santos Alonso, Evangelos J. Giamarellos-Bourboulis, Maria Mouktaroudi, Neskuts Izagirre, Din Syafruddin, Gibson Kibiki, Tudor Cristea, Anneke Hijmans, Lutz Hamann, Shoshana Israel, Gehad ElGhazali, Marita Troye-Blomberg, Oliver Kumpf, Boubacar Maiga, Amagana Dolo, Ogobara Doumbo, Cornelus C. Hermsen, Anton F. H. Stalenhoef, Reinout van Crevel, Han G. Brunner, Djin-Ye Oh, Ralf R. Schumann, Concepcion de la Rúa, Robert Sauerwein, Bart-Jan Kullberg, André J. A. M. van der Ven, Jos W. M. van der Meer, and Mihai G. Netea PMCID: PMC2034238 Medical Sciences Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction Peter J. Coffey, Carlos Gias, Caroline J. McDermott, Peter Lundh, Matthew C. Pickering, Charanjit Sethi, Alan Bird, Fred W. Fitzke, Annelie Maass, Li Li Chen, Graham E. Holder, Philip J. Luthert, Thomas E. Salt, Stephen E. Moss, and John Greenwood PMCID: PMC2034255 A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling James W. Wisler, Scott M. DeWire, Erin J. Whalen, Jonathan D. Violin, Matthew T. Drake, Seungkirl Ahn, Sudha K. Shenoy, and Robert J. Lefkowitz PMCID: PMC2034221 Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer Jude Kendall, Qing Liu, Amy Bakleh, Alex Krasnitz, Ken C. Q. Nguyen, B. Lakshmi, William L. Gerald, Scott Powers, and David Mu PMCID: PMC2034240 Microbiology Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract M. Chelsea Lane, Christopher J. Alteri, Sara N. Smith, and Harry L. T. Mobley PMCID: PMC2034267 Neuroscience Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition Zhengqing Hu and Jeffrey T. Corwin PMCID: PMC1994140 From the Cover:
Centrally released oxytocin mediates mating-induced anxiolysis in male rats Martin Waldherr and Inga D. Neumann PMCID: PMC2034242 A small-molecule therapeutic lead for Huntington's disease: Preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse Vanita Chopra, Jonathan H. Fox, Greg Lieberman, Kathryn Dorsey, Wayne Matson, Peter Waldmeier, David E. Housman, Aleksey Kazantsev, Anne B. Young, and Steven Hersch PMCID: PMC2034257 Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission Norio Wada, Yasushi Kishimoto, Dai Watanabe, Masanobu Kano, Tomoo Hirano, Kazuo Funabiki, and Shigetada Nakanishi PMCID: PMC2034211 Physiology MAL decreases the internalization of the aquaporin-2 water channel Erik-Jan Kamsteeg, Amy S. Duffield, Irene B. M. Konings, Joanna Spencer, Philipp Pagel, Peter M. T. Deen, and Michael J. Caplan PMCID: PMC2034241 Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice Kazutake Tsujikawa, Katsutoshi Yayama, Tamon Hayashi, Hiroaki Matsushita, Taijiro Yamaguchi, Tomomi Shigeno, Yusuke Ogitani, Megumi Hirayama, Tetsuya Kato, So-ichiro Fukada, Shingo Takatori, Hiromu Kawasaki, Hiroshi Okamoto, Masahito Ikawa, Masaru Okabe, and Hiroshi Yamamoto PMCID: PMC2034234 Mammary gland homeostasis employs serotonergic regulation of epithelial tight junctions Malinda A. Stull, Vaibhav Pai, Archie J. Vomachka, Aaron M. Marshall, George A. Jacob, and Nelson D. Horseman PMCID: PMC2034263 Plant Biology Control of corolla monosymmetry in the Brassicaceae Iberis amara Andrea Busch and Sabine Zachgo PMCID: PMC2034219 Social Sciences Agricultural Sciences A multifunctional desaturase involved in the biosynthesis of the processionary moth sex pheromone Montserrat Serra, Benjamin Piña, José Luis Abad, Francisco Camps, and Gemma Fabriàs PMCID: PMC2034215 Psychology Category-specific attention for animals reflects ancestral priorities, not expertise Joshua New, Leda Cosmides, and John Tooby PMCID: PMC2034212 |
