| | This journal provides immediate access to some articles. Commentary IL-1β: An endosomal exit Mark D. Wewers PMCID: PMC478557 Physical Sciences Applied Physical Sciences Pattern formation of stationary transcellular ionic currents in Fucus M. Léonetti, E. Dubois-Violette, and F. Homblé PMCID: PMC478558 Chemistry Enhanced (hydrodynamic) transport induced by population growth in reaction–diffusion systems with application to population genetics Marcel Ovidiu Vlad, L. Luca Cavalli-Sforza, and John Ross PMCID: PMC478559 Biological Sciences Biochemistry Insight into the PrPC → PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants Frédéric Eghiaian, Jeanne Grosclaude, Stéphanie Lesceu, Pascale Debey, Bénédicte Doublet, Eric Tréguer, Human Rezaei, and Marcel Knossow PMCID: PMC478560 A freestanding proofreading domain is required for protein synthesis quality control in Archaea Dragana Korencic, Ivan Ahel, James Schelert, Meik Sacher, Benfang Ruan, Constantinos Stathopoulos, Paul Blum, Michael Ibba, and Dieter Söll PMCID: PMC478561 From the Cover:
Switching desaturase enzyme specificity by alternate subcellular targeting Ingo Heilmann, Mark S. Pidkowich, Thomas Girke, and John Shanklin PMCID: PMC478599 Biophysics The 70-kDa heat shock protein chaperone nucleotide-binding domain in solution unveiled as a molecular machine that can reorient its functional subdomains Yongbo Zhang and Erik R. P. Zuiderweg PMCID: PMC478562 Template-assisted filament growth by parallel stacking of tau Martin Margittai and Ralf Langen PMCID: PMC478563 The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity Sylvie Doublié, Viswanath Bandaru, Jeffrey P. Bond, and Susan S. Wallace PMCID: PMC478564 Cell Biology From the Cover:
Mitochondrial “swirls” induced by oxygen stress and in the Drosophila mutant hyperswirl David W. Walker and Seymour Benzer PMCID: PMC478565 The serine/threonine kinase cyclin G-associated kinase regulates epidermal growth factor receptor signaling Lei Zhang, Ole Gjoerup, and Thomas M. Roberts PMCID: PMC478566 A family of Acrp30/adiponectin structural and functional paralogs Guang W. Wong, Jin Wang, Christopher Hug, Tsu-Shuen Tsao, and Harvey F. Lodish PMCID: PMC478567 T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin Christopher Hug, Jin Wang, Naina Shehzeen Ahmad, Jonathan S. Bogan, Tsu-Shuen Tsao, and Harvey F. Lodish PMCID: PMC478568 A role for Gα12/Gα13 in p120ctn regulation Beate F. Krakstad, Vandana V. Ardawatia, and Anna M. Aragay PMCID: PMC478569 Developmental Biology Retinoic acid influences anteroposterior positioning of epidermal sensory neurons and their gene expression in a developing chordate (amphioxus) Michael Schubert, Nicholas D. Holland, Hector Escriva, Linda Z. Holland, and Vincent Laudet PMCID: PMC478570 Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation Toshio Hamatani, Takiko Daikoku, Haibin Wang, Hiromichi Matsumoto, Mark G. Carter, Minoru S. H. Ko, and Sudhansu K. Dey PMCID: PMC478571 Thyroid hormone receptor α is a molecular switch of cardiac function between fetal and postnatal life Wilfried Mai, Marc F. Janier, Nathalie Allioli, Laure Quignodon, Thomas Chuzel, Frédéric Flamant, and Jacques Samarut PMCID: PMC478572 Nanos suppresses somatic cell fate in Drosophila germ line Yoshiki Hayashi, Makoto Hayashi, and Satoru Kobayashi PMCID: PMC478573 AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons Francesca M. Theriault, Priscillia Roy, and Stefano Stifani PMCID: PMC478574 Evolution Distribution of short paired duplications in mammalian genomes Elizabeth E. Thomas, Nathan Srebro, Jonathan Sebat, Nicholas Navin, John Healy, Bud Mishra, and Michael Wigler PMCID: PMC478600 Surviving the ice: Northern refugia and postglacial colonization Kevin C. Rowe, Edward J. Heske, Patrick W. Brown, and Ken N. Paige PMCID: PMC478575 From the Cover:
Biophysical constraints on the origin of leaves inferred from the fossil record C. P. Osborne, D. J. Beerling, B. H. Lomax, and W. G. Chaloner PMCID: PMC478576 Information constraints and the precision of adaptation: Sex ratio manipulation in wasps David M. Shuker and Stuart A. West PMCID: PMC478577 From the Cover:
Mitochondrial-type assembly of FeS centers in the hydrogenosomes of the amitochondriate eukaryote Trichomonas vaginalis Robert Sutak, Pavel Dolezal, Heather L. Fiumera, Ivan Hrdy, Andrew Dancis, Maria Delgadillo-Correa, Patricia J. Johnson, Miklós Müller, and Jan Tachezy PMCID: PMC478578 Functionally reproductive diploid and haploid males in an inbreeding hymenopteran with complementary sex determination David P. Cowan and Julie K. Stahlhut PMCID: PMC478579 Genetics Enhanced (hydrodynamic) transport induced by population growth in reaction–diffusion systems with application to population genetics Marcel Ovidiu Vlad, L. Luca Cavalli-Sforza, and John Ross PMCID: PMC478559 Cre-lox-regulated conditional RNA interference from transgenes Andrea Ventura, Alexander Meissner, Christopher P. Dillon, Michael McManus, Phillip A. Sharp, Luk Van Parijs, Rudolf Jaenisch, and Tyler Jacks PMCID: PMC478580 A demonstration and findings of a statistical approach through reanalysis of inflammatory bowel disease data Shaw-Hwa Lo and Tian Zheng PMCID: PMC478581 Immunology Direct interaction between FcγRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity Jeffrey M. Beekman, Jantine E. Bakema, Jan G. J. van de Winkel, and Jeanette H. W. Leusen PMCID: PMC478582 Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease Silke Paust, Linrong Lu, Nami McCarty, and Harvey Cantor PMCID: PMC478583 Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc Gianluca Moroncini, Nnennaya Kanu, Laura Solforosi, Gil Abalos, Glenn C. Telling, Mark Head, James Ironside, Jeremy P. Brockes, Dennis R. Burton, and R. Anthony Williamson PMCID: PMC478584 Ligation of CD8 leads to apoptosis of thymocytes that have not undergone positive selection Kristie M. Grebe, Raedun L. Clarke, and Terry A. Potter PMCID: PMC478585 Medical Sciences From the Cover:
Treating cocaine addiction with viruses M. Rocio A. Carrera, Gunnar F. Kaufmann, Jenny M. Mee, Michael M. Meijler, George F. Koob, and Kim D. Janda PMCID: PMC478586 Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse Kohjiro Ueki, Tatsuya Kondo, Yu-Hua Tseng, and C. Ronald Kahn PMCID: PMC478587 Lamin B1 is required for mouse development and nuclear integrity Laurent Vergnes, Miklós Péterfy, Martin O. Bergo, Stephen G. Young, and Karen Reue PMCID: PMC478588 Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity Bulent O. Yildiz, Marc A. Suchard, Ma-Li Wong, Samuel M. McCann, and Julio Licinio PMCID: PMC478601 Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of β2 integrin gene expression Tianqing Kong, Holger K. Eltzschig, Jorn Karhausen, Sean P. Colgan, and C. Simon Shelley PMCID: PMC478589 Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage Xiangqun Gao and Paul Talalay PMCID: PMC478590 Microbiology The evolution of H5N1 influenza viruses in ducks in southern China H. Chen, G. Deng, Z. Li, G. Tian, Y. Li, P. Jiao, L. Zhang, Z. Liu, R. G. Webster, and K. Yu PMCID: PMC478602 Neuroscience Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes Alexander W. Bruce, Ian J. Donaldson, Ian C. Wood, Sally A. Yerbury, Michael I. Sadowski, Michael Chapman, Berthold Göttgens, and Noel J. Buckley PMCID: PMC478591 Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release Nadia De Mota, Annabelle Reaux-Le Goazigo, Said El Messari, Nicolas Chartrel, Darren Roesch, Cynthia Dujardin, Claude Kordon, Hubert Vaudry, Françoise Moos, and Catherine Llorens-Cortes PMCID: PMC478592 Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests Tamas Bartfai, Xiaoying Lu, Hedieh Badie-Mahdavi, Alasdair M. Barr, Andrey Mazarati, Xiao-Ying Hua, Tony Yaksh, Gebhard Haberhauer, Susana Conde Ceide, Laurent Trembleau, Laszlo Somogyi, Lenz Kröck, and Julius Rebek, Jr. PMCID: PMC478593 Learning modulates the ensemble representations for odors in primary olfactory networks Kevin C. Daly, Thomas A. Christensen, Hong Lei, Brian H. Smith, and John G. Hildebrand PMCID: PMC478594 Physiology Lipid- and mechanosensitivities of sodium/hydrogen exchangers analyzed by electrical methods Daniel Fuster, Orson W. Moe, and Donald W. Hilgemann PMCID: PMC478595 Plant Biology Pattern formation of stationary transcellular ionic currents in Fucus M. Léonetti, E. Dubois-Violette, and F. Homblé PMCID: PMC478558 Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport Carola Holweg and Peter Nick PMCID: PMC478596 Corrections Proc Natl Acad Sci U S A. 2004 July 13; 101(28): 10494. doi: 10.1073/pnas.0403640101.PMCID: PMC478597 Corrects: Tetsufumi Koike, et al. Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A. 2004 May 25; 101(21): 8132–8137. Proc Natl Acad Sci U S A. 2004 July 13; 101(28): 10494. doi: 10.1073/pnas.0403922101.PMCID: PMC478598 Corrects: Robert M. Bachoo, et al. Molecular diversity of astrocytes with implications for neurological disorders. Proc Natl Acad Sci U S A. 2004 June 1; 101(22): 8384–8389. |
