| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 April 3; 104(14): 5705–5706. doi: 10.1073/iti1407104.PMCID: PMC1851552 Commentaries Fish extinctions and ecosystem functioning in tropical ecosystems Daniel E. Schindler PMCID: PMC1851553 Further evidence of the safety of assisted reproductive technologies Zev Rosenwaks and Kristin Bendikson PMCID: PMC1851554 Homogenous rivers, homogenous faunas Peter B. Moyle and Jeffrey F. Mount PMCID: PMC1851555 Natural killer T cells: Know thyself Mitchell Kronenberg and Laurent Gapin PMCID: PMC1851556 Physical Sciences Applied Physical Sciences From the Cover:
Micromechanical control of cell–cell interactions Elliot E. Hui and Sangeeta N. Bhatia PMCID: PMC1851558 Chemistry High-pressure/low-temperature neutron scattering of gas inclusion compounds: Progress and prospects Yusheng Zhao, Hongwu Xu, Luke L. Daemen, Konstantin Lokshin, Kimberly T. Tait, Wendy L. Mao, Junhua Luo, Robert P. Currier, and Donald D. Hickmott PMCID: PMC1832222 Destruction of long-range interactions by a single mutation in lysozyme Ruhong Zhou, Maria Eleftheriou, Ajay K. Royyuru, and Bruce J. Berne PMCID: PMC1851576 Environmental Sciences From the Cover:
Homogenization of regional river dynamics by dams and global biodiversity implications N. LeRoy Poff, Julian D. Olden, David M. Merritt, and David M. Pepin PMCID: PMC1851560 Projected distributions of novel and disappearing climates by 2100 AD John W. Williams, Stephen T. Jackson, and John E. Kutzbach PMCID: PMC1851561 20th-Century doubling in dust archived in an Antarctic Peninsula ice core parallels climate change and desertification in South America Joseph R. McConnell, Alberto J. Aristarain, J. Ryan Banta, P. Ross Edwards, and Jefferson C. Simões PMCID: PMC1851562 Geophysics Thermodynamic constraints on stochastic acceleration in compressional turbulence Lennard A. Fisk and George Gloeckler PMCID: PMC1829328 Physics Estimation of critical exponents from cluster coefficients and the application of this estimation to hard spheres E. Eisenberg and A. Baram PMCID: PMC1851564 Biological Sciences Biochemistry Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger Santina Bruzzone, Iliana Moreschi, Cesare Usai, Lucrezia Guida, Gianluca Damonte, Annalisa Salis, Sonia Scarfì, Enrico Millo, Antonio De Flora, and Elena Zocchi PMCID: PMC1832220 The p23 molecular chaperone promotes functional telomerase complexes through DNA dissociation Oyetunji A. Toogun, Will Zeiger, and Brian C. Freeman PMCID: PMC1851566 Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway Ami S. Bhatt, Alana Welm, Christopher J. Farady, Maximiliano Vásquez, Keith Wilson, and Charles S. Craik PMCID: PMC1838401 Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase Tsunehiro Mizushima, Yukiko Yoshida, Taichi Kumanomidou, Yuko Hasegawa, Atsuo Suzuki, Takashi Yamane, and Keiji Tanaka PMCID: PMC1851568 From the Cover:
Structural insight into substrate specificity of phosphodiesterase 10 Huanchen Wang, Yudong Liu, Jing Hou, Meiyan Zheng, Howard Robinson, and Hengming Ke PMCID: PMC1851569 Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex Robert J. C. Gilbert, Yulya Gordiyenko, Tobias von der Haar, Andreas F.-P. Sonnen, Gregor Hofmann, Maria Nardelli, David I. Stuart, and John E. G. McCarthy PMCID: PMC1832216 Estrogen receptor α is a putative substrate for the BRCA1 ubiquitin ligase Catherine M. Eakin, Michael J. MacCoss, Gregory L. Finney, and Rachel E. Klevit PMCID: PMC1851571 Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Mihoko Takahashi, Youhei Kondou, and Chikashi Toyoshima PMCID: PMC1851572 Extrachromosomal element capture and the evolution of multiple replication origins in archaeal chromosomes Nicholas P. Robinson and Stephen D. Bell PMCID: PMC1851573 Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis Elenita I. Kanin, Ryan T. Kipp, Charles Kung, Matthew Slattery, Agnes Viale, Steven Hahn, Kevan M. Shokat, and Aseem Z. Ansari PMCID: PMC1851574 Evidence for proton transfer in the rate-limiting step of a fast-cleaving Varkud satellite ribozyme M. Duane Smith and Richard A. Collins PMCID: PMC1851575 Biophysics Destruction of long-range interactions by a single mutation in lysozyme Ruhong Zhou, Maria Eleftheriou, Ajay K. Royyuru, and Bruce J. Berne PMCID: PMC1851576 Correlation between mechanical strength of messenger RNA pseudoknots and ribosomal frameshifting Thomas M. Hansen, S. Nader S. Reihani, Lene B. Oddershede, and Michael A. Sørensen PMCID: PMC1838403 Cell Biology CCR4/NOT complex associates with the proteasome and regulates histone methylation R. Nicholas Laribee, Yoichiro Shibata, Douglas P. Mersman, Sean R. Collins, Patrick Kemmeren, Assen Roguev, Jonathan S. Weissman, Scott D. Briggs, Nevan J. Krogan, and Brian D. Strahl PMCID: PMC1851578 Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons Xiang Zhou, J. Ramesh Babu, Susana da Silva, Qing Shu, Isabella A. Graef, Tim Oliver, Toshifumi Tomoda, Tomomi Tani, Marie W. Wooten, and Fan Wang PMCID: PMC1851579 From the Cover:
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins Hua Huang, Fang Sun, David M. Owen, Weiping Li, Yan Chen, Michael Gale, Jr., and Jin Ye PMCID: PMC1829327 Morlin, an inhibitor of cortical microtubule dynamics and cellulose synthase movement Seth DeBolt, Ryan Gutierrez, David W. Ehrhardt, Carlos V. Melo, Loretta Ross, Sean R. Cutler, Christopher Somerville, and Dario Bonetta PMCID: PMC1851581 Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks Alejandro Wolf-Yadlin, Sampsa Hautaniemi, Douglas A. Lauffenburger, and Forest M. White PMCID: PMC1851582 Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1 Qingchang Meng, Suresh K. Rayala, Anupama E. Gururaj, Amjad H. Talukder, Bert W. O'Malley, and Rakesh Kumar PMCID: PMC1851583 Rab27b regulates number and secretion of platelet dense granules Tanya Tolmachova, Magnus Åbrink, Clare E. Futter, Kalwant S. Authi, and Miguel C. Seabra PMCID: PMC1831675 Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties Michelle B. Bowie, David G. Kent, Brad Dykstra, Kristen D. McKnight, Lindsay McCaffrey, Pamela A. Hoodless, and Connie J. Eaves PMCID: PMC1829493 Molecular and electrophysiological characterization of a mechanosensitive channel expressed in the chloroplasts of Chlamydomonas Yoshitaka Nakayama, Kenta Fujiu, Masahiro Sokabe, and Kenjiro Yoshimura PMCID: PMC1851586 Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy Prashant Prabhat, Zhuo Gan, Jerry Chao, Sripad Ram, Carlos Vaccaro, Steven Gibbons, Raimund J. Ober, and E. Sally Ward PMCID: PMC1851587 Developmental Biology Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways Barbara Stecca, Christophe Mas, Virginie Clement, Marie Zbinden, Rafael Correa, Vincent Piguet, Friedrich Beermann, and Ariel Ruiz i Altaba PMCID: PMC1838820 nanos function is essential for development and regeneration of planarian germ cells Yuying Wang, Ricardo M. Zayas, Tingxia Guo, and Phillip A. Newmark PMCID: PMC1851589 Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch Hung Ping Shih, Michael K. Gross, and Chrissa Kioussi PMCID: PMC1851590 Jagged-mediated Notch signaling maintains proliferating neural progenitors and regulates cell diversity in the ventral spinal cord Sang-Yeob Yeo and Ajay B. Chitnis PMCID: PMC1832219 Crucial roles of Foxa2 in mouse anterior–posterior axis polarization via regulation of anterior visceral endoderm-specific genes Chiharu Kimura-Yoshida, E. Tian, Hiroshi Nakano, Saori Amazaki, Kayo Shimokawa, Janet Rossant, Shinichi Aizawa, and Isao Matsuo PMCID: PMC1851592 Ecology From the Cover:
Homogenization of regional river dynamics by dams and global biodiversity implications N. LeRoy Poff, Julian D. Olden, David M. Merritt, and David M. Pepin PMCID: PMC1851560 Projected distributions of novel and disappearing climates by 2100 AD John W. Williams, Stephen T. Jackson, and John E. Kutzbach PMCID: PMC1851561 Global patterns and determinants of vascular plant diversity Holger Kreft and Walter Jetz PMCID: PMC1851593 Coarse-grained analysis of stochasticity-induced switching between collective motion states Allison Kolpas, Jeff Moehlis, and Ioannis G. Kevrekidis PMCID: PMC1851594 Evolution High-resolution species trees without concatenation Scott V. Edwards, Liang Liu, and Dennis K. Pearl PMCID: PMC1851595 Transgenerational epigenetic imprints on mate preference David Crews, Andrea C. Gore, Timothy S. Hsu, Nygerma L. Dangleben, Michael Spinetta, Timothy Schallert, Matthew D. Anway, and Michael K. Skinner PMCID: PMC1851596 Genetics Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex Arjumand Ghazi, Sivan Henis-Korenblit, and Cynthia Kenyon PMCID: PMC1851597 Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C Ahmad Besaratinia, Sang-in Kim, Steven E. Bates, and Gerd P. Pfeifer PMCID: PMC1851598 Metagene projection for cross-platform, cross-species characterization of global transcriptional states Pablo Tamayo, Daniel Scanfeld, Benjamin L. Ebert, Michael A. Gillette, Charles W. M. Roberts, and Jill P. Mesirov PMCID: PMC1838404 Meiotic recombination-related DNA synthesis and its implications for cross-over and non-cross-over recombinant formation Masahiro Terasawa, Hideyuki Ogawa, Yasumasa Tsukamoto, Miki Shinohara, Katsuhiko Shirahige, Nancy Kleckner, and Tomoko Ogawa PMCID: PMC1851600 Immunology From the Cover:
Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals Anneliese O. Speak, Mariolina Salio, David C. A. Neville, Josette Fontaine, David A. Priestman, Nick Platt, Tanya Heare, Terry D. Butters, Raymond A. Dwek, Francois Trottein, Mark A. Exley, Vincenzo Cerundolo, and Frances M. Platt PMCID: PMC1851601 From the Cover:
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency Stefan Porubsky, Anneliese O. Speak, Bruno Luckow, Vincenzo Cerundolo, Frances M. Platt, and Hermann-Josef Gröne PMCID: PMC1851602 Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing Yusuke Mimura, Yuka Mimura-Kimura, Katie Doores, Denise Golgher, Benjamin G. Davis, Raymond A. Dwek, Pauline M. Rudd, and Tim Elliott PMCID: PMC1851603 Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules Anna M. Keller, Tom A. Groothuis, Elise A. M. Veraar, Marije Marsman, Lucas Maillette de Buy Wenniger, Hans Janssen, Jacques Neefjes, and Jannie Borst PMCID: PMC1851604 Medical Sciences Exercise reverses preamyloid oligomer and prolongs survival in αB-crystallin-based desmin-related cardiomyopathy Alina Maloyan, James Gulick, Charles G. Glabe, Rakez Kayed, and Jeffrey Robbins PMCID: PMC1851605 Ott1(Rbm15) has pleiotropic roles in hematopoietic development Glen D. Raffel, Thomas Mercher, Hirokazu Shigematsu, Ifor R. Williams, Dana E. Cullen, Koichi Akashi, Olivier A. Bernard, and D. Gary Gilliland PMCID: PMC1851606 Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides Liutao Du, Julianne M. Pollard, and Richard A. Gatti PMCID: PMC1832221 Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions Shotaro Suzuki, Candice M. Brown, Christopher D. Dela Cruz, Enhua Yang, David A. Bridwell, and Phyllis M. Wise PMCID: PMC1851608 Toll-like receptor-MyD88 and Fc receptor pathways of mast cells mediate the thyroid dysfunctions observed during nonthyroidal illness Roberto Rocchi, Hiroaki Kimura, Shey-Cherng Tzou, Koichi Suzuki, Noel R. Rose, Aldo Pinchera, Paul W. Ladenson, and Patrizio Caturegli PMCID: PMC1851609 Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C Jan M. Pestka, Mirjam B. Zeisel, Edith Bläser, Peter Schürmann, Birke Bartosch, Francois-Loïc Cosset, Arvind H. Patel, Helga Meisel, Jens Baumert, Sergei Viazov, Kay Rispeter, Hubert E. Blum, Michael Roggendorf, and Thomas F. Baumert PMCID: PMC1851610 Microbiology Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy Sylvie Alonso, Kevin Pethe, David G. Russell, and Georgiana E. Purdy PMCID: PMC1851611 In vivo negative selection screen identifies genes required for Francisella virulence David S. Weiss, Anna Brotcke, Thomas Henry, Jeffrey J. Margolis, Kaman Chan, and Denise M. Monack PMCID: PMC1832217 Combinatorial transcriptional control of the lactose operon of Escherichia coli Thomas Kuhlman, Zhongge Zhang, Milton H. Saier, Jr., and Terence Hwa PMCID: PMC1851613 Viral activation and recruitment of metacaspases in the unicellular coccolithophore, Emiliania huxleyi Kay D. Bidle, Liti Haramaty, Joana Barcelos e Ramos, and Paul Falkowski PMCID: PMC1838821 Neuroscience Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors Paul J. Kammermeier and Paul F. Worley PMCID: PMC1851615 Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia Mary M. Lunzer, Ajay Yekkirala, Robert P. Hebbel, and Philip S. Portoghese PMCID: PMC1851616 Neural encoding of the concept of nest in the mouse brain Longnian Lin, Guifen Chen, Hui Kuang, Dong Wang, and Joe Z. Tsien PMCID: PMC1851617 Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology Marjatta Son, Krishna Puttaparthi, Hibiki Kawamata, Bhagya Rajendran, Philip J. Boyer, Giovanni Manfredi, and Jeffrey L. Elliott PMCID: PMC1851618 Cytosolic phospholipase A2 alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatment Ying Shen, Koji Kishimoto, David J. Linden, and Adam Sapirstein PMCID: PMC1851619 Pharmacology INAUGURAL ARTICLE by a Recently Elected Academy Member: Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA Jeremy D. Heidel, Zhongping Yu, Joanna Yi-Ching Liu, Shyam M. Rele, Yongchao Liang, Ryan K. Zeidan, Douglas J. Kornbrust, and Mark E. Davis PMCID: PMC1829492 Psychology Genomic imprinting mediates sexual experience-dependent olfactory learning in male mice William T. Swaney, James P. Curley, Frances A. Champagne, and Eric B. Keverne PMCID: PMC1851620 Sustainability Science From the Cover:
Homogenization of regional river dynamics by dams and global biodiversity implications N. LeRoy Poff, Julian D. Olden, David M. Merritt, and David M. Pepin PMCID: PMC1851560 Corrections Correction for Moehle et al., Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases PMCID: PMC1851621 Corrects: Erica A. Moehle, et al. Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases. Proc Natl Acad Sci U S A. 2007 February 27; 104(9): 3055–3060. Correction for Manuelidis et al., Cells infected with scrapie and Creutzfeldt–Jakob disease agents produce intracellular 25-nm virus-like particles PMCID: PMC1851622 Corrects: Laura Manuelidis, et al. Cells infected with scrapie and Creutzfeldt–Jakob disease agents produce intracellular 25-nm virus-like particles. Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1965–1970. |
