| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4241–4242. doi: 10.1073/iti1107104.PMCID: PMC1838584 Commentaries Regulation of carbon and nitrogen metabolism: Adding regulation of ion channels and another second messenger to the mix Alexander J. Ninfa Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4243–4244. Published online 2007 March 7. doi: 10.1073/pnas.0700325104.PMCID: PMC1838585 New mouse models of cancer: Single-cell knockouts Guillermina Lozano and Richard R. Behringer Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4245–4246. Published online 2007 March 5. doi: 10.1073/pnas.0700173104.PMCID: PMC1838586 Where's the water? Hydrotropism in plants John Z. Kiss Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4247–4248. Published online 2007 March 12. doi: 10.1073/pnas.0700846104.PMCID: PMC1838587 Physical Sciences Applied Mathematics Haplotype structure and selection of the MDM2 oncogene in humans Gurinder Singh Atwal, Gareth L. Bond, Sally Metsuyanim, Moshe Papa, Eitan Friedman, Tal Distelman-Menachem, Edna Ben Asher, Doron Lancet, David A. Ross, John Sninsky, Tomas J. White, Arnold J. Levine, and Ronit Yarden Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4524–4529. Published online 2007 March 5. doi: 10.1073/pnas.0610998104.PMCID: PMC1838634 Environmental Sciences The changing carbon cycle at Mauna Loa Observatory Wolfgang Buermann, Benjamin R. Lintner, Charles D. Koven, Alon Angert, Jorge E. Pinzon, Compton J. Tucker, and Inez Y. Fung Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4249–4254. doi: 10.1073/pnas.0611224104.PMCID: PMC1810339 Biological Sciences Anthropology Nonlinear scaling of space use in human hunter–gatherers Marcus J. Hamilton, Bruce T. Milne, Robert S. Walker, and James H. Brown Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4765–4769. Published online 2007 March 6. doi: 10.1073/pnas.0611197104.PMCID: PMC1810510 Applied Biological Sciences Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets Anubhav Arora, Itzhak Hakim, Joy Baxter, Ruben Rathnasingham, Ravi Srinivasan, Daniel A. Fletcher, and Samir Mitragotri Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4255–4260. Published online 2007 March 6. doi: 10.1073/pnas.0700182104.PMCID: PMC1838589 Biochemistry Drug target interaction energies by the kernel energy method in aminoglycoside drugs and ribosomal A site RNA targets Lulu Huang, Lou Massa, and Jerome Karle Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4261–4266. Published online 2007 March 1. doi: 10.1073/pnas.0610533104.PMCID: PMC1838590 Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases Christian Castro, Eric Smidansky, Kenneth R. Maksimchuk, Jamie J. Arnold, Victoria S. Korneeva, Matthias Götte, William Konigsberg, and Craig E. Cameron Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4267–4272. Published online 2007 March 5. doi: 10.1073/pnas.0608952104.PMCID: PMC1838591 A female-biased expressed elongase involved in long-chain hydrocarbon biosynthesis and courtship behavior in Drosophila melanogaster Thomas Chertemps, Line Duportets, Carole Labeur, Ryu Ueda, Kuniaki Takahashi, Kaoru Saigo, and Claude Wicker-Thomas Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4273–4278. Published online 2007 March 6. doi: 10.1073/pnas.0608142104.PMCID: PMC1838592 Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate Dmitry A. Rodionov, Oleg V. Kurnasov, Boguslaw Stec, Yan Wang, Mary F. Roberts, and Andrei L. Osterman Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4279–4284. Published online 2007 March 2. doi: 10.1073/pnas.0609279104.PMCID: PMC1838593 Relationship between the structure of SET/TAF-Iβ/INHAT and its histone chaperone activity Shinsuke Muto, Miki Senda, Yusuke Akai, Lui Sato, Toru Suzuki, Ryozo Nagai, Toshiya Senda, and Masami Horikoshi Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4285–4290. Published online 2007 March 6. doi: 10.1073/pnas.0603762104.PMCID: PMC1810507 Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity Chen Davidovich, Anat Bashan, Tamar Auerbach-Nevo, Rachel D. Yaggie, Richard R. Gontarek, and Ada Yonath Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4291–4296. Published online 2007 March 8. doi: 10.1073/pnas.0700041104.PMCID: PMC1817833 Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains Liang Guo, Aidong Han, Darren L. Bates, Jue Cao, and Lin Chen Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4297–4302. Published online 2007 March 5. doi: 10.1073/pnas.0608041104.PMCID: PMC1838596 Production and characterization of monoclonal antibodies sensitive to conformation in the 5HT2c serotonin receptor Filippo Mancia, Susan Brenner-Morton, Risa Siegel, Zahra Assur, Yonghua Sun, Ira Schieren, Monica Mendelsohn, Richard Axel, and Wayne A. Hendrickson Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4303–4308. Published online 2007 March 6. doi: 10.1073/pnas.0700301104.PMCID: PMC1838597 Spiral structure of Escherichia coli HUαβ provides foundation for DNA supercoiling Fusheng Guo and Sankar Adhya Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4309–4314. Published online 2007 March 5. doi: 10.1073/pnas.0611686104.PMCID: PMC1838598 Structure and function of a hexameric copper-containing nitrite reductase Masaki Nojiri, Yong Xie, Tsuyoshi Inoue, Takahiko Yamamoto, Hiroyoshi Matsumura, Kunishige Kataoka, Deligeer, Kazuya Yamaguchi, Yasushi Kai, and Shinnichiro Suzuki Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4315–4320. Published online 2007 March 5. doi: 10.1073/pnas.0609195104.PMCID: PMC1838599 Structure and reactivity of LpxD, the N-acyltransferase of lipid A biosynthesis Lori Buetow, Terry K. Smith, Alice Dawson, Stewart Fyffe, and William N. Hunter Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4321–4326. Published online 2007 March 5. doi: 10.1073/pnas.0606356104.PMCID: PMC1810333 Studies of nucleotide binding to the catalytic sites of Escherichia coli βY331W-F1-ATPase using fluorescence quenching Vladimir V. Bulygin and Yakov M. Milgrom Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4327–4331. Published online 2007 March 5. doi: 10.1073/pnas.0700078104.PMCID: PMC1838601 Biophysics From the Cover: Myosin Va maneuvers through actin intersections and diffuses along microtubules M. Yusuf Ali, Elena B. Krementsova, Guy G. Kennedy, Rachel Mahaffy, Thomas D. Pollard, Kathleen M. Trybus, and David M. Warshaw Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4332–4336. Published online 2007 February 23. doi: 10.1073/pnas.0611471104.PMCID: PMC1838602 Predicting protein–protein interactions based only on sequences information Juwen Shen, Jian Zhang, Xiaomin Luo, Weiliang Zhu, Kunqian Yu, Kaixian Chen, Yixue Li, and Hualiang Jiang Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4337–4341. Published online 2007 March 5. doi: 10.1073/pnas.0607879104.PMCID: PMC1838603 Insight into the selectivity and gating functions of Streptomyces lividans KcsA Alexander Negoda, Mo Xian, and Rosetta N. Reusch Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4342–4346. Published online 2007 March 6. doi: 10.1073/pnas.0700495104.PMCID: PMC1838604 Functional residues serve a dominant role in mediating the cooperativity of the protein ensemble Tong Liu, Steven T. Whitten, and Vincent J. Hilser Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4347–4352. Published online 2007 March 5. doi: 10.1073/pnas.0607132104.PMCID: PMC1838605 Domain-swapped dimerization of the HIV-1 capsid C-terminal domain Dmitri Ivanov, Oleg V. Tsodikov, Jeremy Kasanov, Tom Ellenberger, Gerhard Wagner, and Tucker Collins Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4353–4358. Published online 2007 March 5. doi: 10.1073/pnas.0609477104.PMCID: PMC1838606 MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST) Peter C. M. van Zijl, Craig K. Jones, Jimin Ren, Craig R. Malloy, and A. Dean Sherry Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4359–4364. Published online 2007 March 5. doi: 10.1073/pnas.0700281104.PMCID: PMC1838607 Cell Biology Dose-dependent cross-talk between the transforming growth factor-β and interleukin-1 signaling pathways Tao Lu, Liping Tian, Yulong Han, Michael Vogelbaum, and George R. Stark Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4365–4370. Published online 2007 March 5. doi: 10.1073/pnas.0700118104.PMCID: PMC1810327 Gαi2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation Ralph S. Pero, Michael T. Borchers, Karsten Spicher, Sergei I. Ochkur, Lyudmila Sikora, Savita P. Rao, Hiam Abdala-Valencia, Katie R. O'Neill, Huahao Shen, Michael P. McGarry, Nancy A. Lee, Joan M. Cook-Mills, P. Sriramarao, Melvin I. Simon, Lutz Birnbaumer, and James J. Lee Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4371–4376. Published online 2007 March 7. doi: 10.1073/pnas.0700185104.PMCID: PMC1838609 Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction Jens Fielitz, Eva van Rooij, Jeffrey A. Spencer, John M. Shelton, Shuaib Latif, Roel van der Nagel, Svetlana Bezprozvannaya, Leon de Windt, James A. Richardson, Rhonda Bassel-Duby, and Eric N. Olson Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4377–4382. Published online 2007 March 2. doi: 10.1073/pnas.0611726104.PMCID: PMC1838610 Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells Mark E. Burkard, Catherine L. Randall, Stéphane Larochelle, Chao Zhang, Kevan M. Shokat, Robert P. Fisher, and Prasad V. Jallepalli Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4383–4388. Published online 2007 March 6. doi: 10.1073/pnas.0701140104.PMCID: PMC1838611 Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Stephanie J. Leuenroth, Dayne Okuhara, Joseph D. Shotwell, Glen S. Markowitz, Zhiheng Yu, Stefan Somlo, and Craig M. Crews Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4389–4394. Published online 2007 March 6. doi: 10.1073/pnas.0700499104.PMCID: PMC1838612 Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons Fan Zhang, Jason H. Pomerantz, George Sen, Adam T. Palermo, and Helen M. Blau Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4395–4400. Published online 2007 March 7. doi: 10.1073/pnas.0700181104.PMCID: PMC1838613 Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages James A. Timmons, Kristian Wennmalm, Ola Larsson, Tomas B. Walden, Timo Lassmann, Natasa Petrovic, D. Lee Hamilton, Ruth E. Gimeno, Claes Wahlestedt, Keith Baar, Jan Nedergaard, and Barbara Cannon Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4401–4406. Published online 2007 March 5. doi: 10.1073/pnas.0610615104.PMCID: PMC1810328 EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites Christian Zuber, James H. Cormier, Bruno Guhl, Roger Santimaria, Daniel N. Hebert, and Jürgen Roth Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4407–4412. Published online 2007 March 6. doi: 10.1073/pnas.0700154104.PMCID: PMC1810509 Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells Xiaoqing Liu, Oleg V. Bulgakov, Keith N. Darrow, Basil Pawlyk, Michael Adamian, M. Charles Liberman, and Tiansen Li Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4413–4418. Published online 2007 March 5. doi: 10.1073/pnas.0610950104.PMCID: PMC1838616 β cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo Oliver Strobel, Yuval Dor, Amy Stirman, Amanda Trainor, Carlos Fernández-del Castillo, Andrew L. Warshaw, and Sarah P. Thayer Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4419–4424. Published online 2007 March 7. doi: 10.1073/pnas.0605248104.PMCID: PMC1815470 p53-dependent integration of telomere and growth factor deprivation signals Alain Beliveau, Ekaterina Bassett, Alvin T. Lo, James Garbe, Miguel A. Rubio, Mina J. Bissell, Judith Campisi, and Paul Yaswen Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4431–4436. Published online 2007 March 5. doi: 10.1073/pnas.0700260104.PMCID: PMC1838618 Developmental Biology The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia Catherine Carrière, Elliott S. Seeley, Tobias Goetze, Daniel S. Longnecker, and Murray Korc Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4437–4442. Published online 2007 March 5. doi: 10.1073/pnas.0701117104.PMCID: PMC1810329 RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells Elena Vasyutina, Diana C. Lenhard, Hagen Wende, Bettina Erdmann, Jonathan A. Epstein, and Carmen Birchmeier Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4443–4448. Published online 2007 March 7. doi: 10.1073/pnas.0610647104.PMCID: PMC1815471 A pure population of lung alveolar epithelial type II cells derived from human embryonic stem cells Dachun Wang, David L. Haviland, Alan R. Burns, Eva Zsigmond, and Rick A. Wetsel Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4449–4454. Published online 2007 March 2. doi: 10.1073/pnas.0700052104.PMCID: PMC1838621 Developmental and adult phenotyping directly from mutant embryonic stem cells Sophia H. L. George, Marina Gertsenstein, Kristina Vintersten, Ella Korets-Smith, John Murphy, Mary E. Stevens, Jody J. Haigh, and Andras Nagy Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4455–4460. Published online 2007 March 2. doi: 10.1073/pnas.0609277104.PMCID: PMC1838622 Environmental Sciences From the Cover: Fish extinctions alter nutrient recycling in tropical freshwaters Peter B. McIntyre, Laura E. Jones, Alexander S. Flecker, and Michael J. Vanni Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4461–4466. Published online 2007 February 20. doi: 10.1073/pnas.0608148104.PMCID: PMC1838623 Evolution Novel sex pheromone desaturases in the genomes of corn borers generated through gene duplication and retroposon fusion Bingye Xue, Alejandro P. Rooney, Masaki Kajikawa, Norihiro Okada, and Wendell L. Roelofs Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4467–4472. Published online 2007 March 5. doi: 10.1073/pnas.0700422104.PMCID: PMC1838624 A statistical phylogeography of influenza A H5N1 Robert G. Wallace, HoangMinh HoDac, Richard H. Lathrop, and Walter M. Fitch Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4473–4478. Published online 2007 March 7. doi: 10.1073/pnas.0700435104.PMCID: PMC1838625 Retaliatory mafia behavior by a parasitic cowbird favors host acceptance of parasitic eggs Jeffrey P. Hoover and Scott K. Robinson Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4479–4483. Published online 2007 March 5. doi: 10.1073/pnas.0609710104.PMCID: PMC1838626 Experimental constraints on mate preferences in Drosophila pseudoobscura decrease offspring viability and fitness of mated pairs Wyatt W. Anderson, Yong-Kyu Kim, and Patricia Adair Gowaty Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4484–4488. Published online 2007 March 6. doi: 10.1073/pnas.0611152104.PMCID: PMC1838627 Global extent of horizontal gene transfer In-Geol Choi and Sung-Hou Kim Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4489–4494. Published online 2007 March 7. doi: 10.1073/pnas.0611557104.PMCID: PMC1815472 Genetics From the Cover: Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM) Mandar Deepak Muzumdar, Liqun Luo, and Hui Zong Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4495–4500. Published online 2007 March 5. doi: 10.1073/pnas.0606491104.PMCID: PMC1810340 From the Cover: Induced mitotic recombination of p53 in vivo Wei Wang, Madhuri Warren, and Allan Bradley Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4501–4505. Published online 2007 March 5. doi: 10.1073/pnas.0607953104.PMCID: PMC1838630 Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency Carmine Settembre, Ida Annunziata, Carmine Spampanato, Daniela Zarcone, Gilda Cobellis, Edoardo Nusco, Ester Zito, Carlo Tacchetti, Maria Pia Cosma, and Andrea Ballabio Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4506–4511. Published online 2007 March 6. doi: 10.1073/pnas.0700382104.PMCID: PMC1810506 Impaired FGF signaling contributes to cleft lip and palate Bridget M. Riley, M. Adela Mansilla, Jinghong Ma, Sandra Daack-Hirsch, Brion S. Maher, Lisa M. Raffensperger, Erilynn T. Russo, Alexandre R. Vieira, Catherine Dodé, Moosa Mohammadi, Mary L. Marazita, and Jeffrey C. Murray Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4512–4517. Published online 2007 March 6. doi: 10.1073/pnas.0607956104.PMCID: PMC1810508 Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells Shan Zha, Frederick W. Alt, Hwei-Ling Cheng, James W. Brush, and Gang Li Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4518–4523. Published online 2007 March 7. doi: 10.1073/pnas.0611734104.PMCID: PMC1838633 Haplotype structure and selection of the MDM2 oncogene in humans Gurinder Singh Atwal, Gareth L. Bond, Sally Metsuyanim, Moshe Papa, Eitan Friedman, Tal Distelman-Menachem, Edna Ben Asher, Doron Lancet, David A. Ross, John Sninsky, Tomas J. White, Arnold J. Levine, and Ronit Yarden Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4524–4529. Published online 2007 March 5. doi: 10.1073/pnas.0610998104.PMCID: PMC1838634 Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics Haijin Meng, Iset Vera, Nam Che, Xuping Wang, Susanna S. Wang, Leslie Ingram-Drake, Eric E. Schadt, Thomas A. Drake, and Aldons J. Lusis Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4530–4535. Published online 2007 March 6. doi: 10.1073/pnas.0607620104.PMCID: PMC1838635 Role of RNA polymerase IV in plant small RNA metabolism Xiaoyu Zhang, Ian R. Henderson, Cheng Lu, Pamela J. Green, and Steven E. Jacobsen Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4536–4541. Published online 2007 March 5. doi: 10.1073/pnas.0611456104.PMCID: PMC1810338 Immunology Division and differentiation of natural antibody-producing cells in mouse spleen Yang Yang, James W. Tung, Eliver E. B. Ghosn, Leonard A. Herzenberg, and Leonore A. Herzenberg Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4542–4546. Published online 2007 March 7. doi: 10.1073/pnas.0700001104.PMCID: PMC1838637 Importance of culturing primary lymphocytes at physiological oxygen levels Kondala R. Atkuri, Leonard A. Herzenberg, Anna-Kaisa Niemi, Tina Cowan, and Leonore A. Herzenberg Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4547–4552. Published online 2007 March 5. doi: 10.1073/pnas.0611732104.PMCID: PMC1838638 Competition for antigen determines the stability of T cell–dendritic cell interactions during clonal expansion Zacarias Garcia, Emmanuelle Pradelli, Susanna Celli, Hélène Beuneu, Aurélie Simon, and Philippe Bousso Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4553–4558. Published online 2007 March 2. doi: 10.1073/pnas.0610019104.PMCID: PMC1838639 Embryonic chimerism does not induce tolerance in an invertebrate model organism Monita Poudyal, Sabrina Rosa, Anahid E. Powell, Maria Moreno, Stephen L. Dellaporta, Leo W. Buss, and Fadi G. Lakkis Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4559–4564. Published online 2007 March 5. doi: 10.1073/pnas.0608696104.PMCID: PMC1838640 Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection Paola Agnellini, Petra Wolint, Manuela Rehr, Julia Cahenzli, Urs Karrer, and Annette Oxenius Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4565–4570. Published online 2007 March 7. doi: 10.1073/pnas.0610335104.PMCID: PMC1815473 FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression Bin Li, Arabinda Samanta, Xiaomin Song, Kathryn T. Iacono, Kathryn Bembas, Ran Tao, Samik Basu, James L. Riley, Wayne W. Hancock, Yuan Shen, Sandra J. Saouaf, and Mark I. Greene Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4571–4576. Published online 2007 March 7. doi: 10.1073/pnas.0700298104.PMCID: PMC1838642 Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules Shan Liao, Kevin Bentley, Marielle Lebrun, Werner Lesslauer, Frank H. Ruddle, and Nancy H. Ruddle Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4577–4582. Published online 2007 March 5. doi: 10.1073/pnas.0700334104.PMCID: PMC1838643 Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity Irina Gavanescu, Benedikt Kessler, Hidde Ploegh, Christophe Benoist, and Diane Mathis Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4583–4587. Published online 2007 March 6. doi: 10.1073/pnas.0700259104.PMCID: PMC1838644 Medical Sciences Impaired angiogenesis in aminopeptidase N-null mice Roberto Rangel, Yan Sun, Liliana Guzman-Rojas, Michael G. Ozawa, Jessica Sun, Ricardo J. Giordano, Carolyn S. Van Pelt, Peggy T. Tinkey, Richard R. Behringer, Richard L. Sidman, Wadih Arap, and Renata Pasqualini Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4588–4593. Published online 2007 March 7. doi: 10.1073/pnas.0611653104.PMCID: PMC1815469 Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment Cornelius Miething, Rebekka Grundler, Claudia Mugler, Simone Brero, Josef Hoepfl, Jochen Geigl, Michael R. Speicher, Oliver Ottmann, Christian Peschel, and Justus Duyster Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4594–4599. Published online 2007 March 5. doi: 10.1073/pnas.0604716104.PMCID: PMC1810334 Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia Bryan L. Krock, Joseph Bilotta, and Brian D. Perkins Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4600–4605. Published online 2007 March 5. doi: 10.1073/pnas.0605818104.PMCID: PMC1810335 Microbiology High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections Lixin Zhang, Kezhi Yan, Yu Zhang, Ren Huang, Jiang Bian, Chuansen Zheng, Haixiang Sun, Zhihui Chen, Nuo Sun, Rong An, Fangui Min, Weibo Zhao, Ying Zhuo, Jianlan You, Yongjie Song, Zhenyan Yu, Zhiheng Liu, Keqian Yang, Hong Gao, Huanqin Dai, Xiaoli Zhang, Jian Wang, Chengzhang Fu, Gang Pei, Jintao Liu, Si Zhang, Michael Goodfellow, Yuanying Jiang, Jun Kuai, Guochun Zhou, and Xiaoping Chen Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4606–4611. Published online 2007 March 5. doi: 10.1073/pnas.0609370104.PMCID: PMC1838648 A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps Sune Lobedanz, Evert Bokma, Martyn F. Symmons, Eva Koronakis, Colin Hughes, and Vassilis Koronakis Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4612–4617. Published online 2007 March 5. doi: 10.1073/pnas.0610160104.PMCID: PMC1838649 Spliced leader RNA trans-splicing in dinoflagellates Huan Zhang, Yubo Hou, Lilibeth Miranda, David A. Campbell, Nancy R. Sturm, Terry Gaasterland, and Senjie Lin Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4618–4623. Published online 2007 March 2. doi: 10.1073/pnas.0700258104.PMCID: PMC1838650 Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections Antonio DiGiandomenico, Jayasimha Rao, Katie Harcher, Tanweer S. Zaidi, Jason Gardner, Alice N. Neely, Gerald B. Pier, and Joanna B. Goldberg Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4624–4629. Published online 2007 March 5. doi: 10.1073/pnas.0608657104.PMCID: PMC1838651 General transcription factor specified global gene regulation in archaea Marc T. Facciotti, David J. Reiss, Min Pan, Amardeep Kaur, Madhavi Vuthoori, Richard Bonneau, Paul Shannon, Alok Srivastava, Samuel M. Donohoe, Leroy E. Hood, and Nitin S. Baliga Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4630–4635. Published online 2007 March 7. doi: 10.1073/pnas.0611663104.PMCID: PMC1838652 Regulation of the stringent response is the essential function of the conserved bacterial G protein CgtA in Vibrio cholerae David M. Raskin, Nicholas Judson, and John J. Mekalanos Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4636–4641. Published online 2007 March 5. doi: 10.1073/pnas.0611650104.PMCID: PMC1838653 Neuroscience Paradoxical influence of hippocampal neurogenesis on working memory Michael D. Saxe, Gaël Malleret, Svetlana Vronskaya, Indira Mendez, A. Denise Garcia, Michael V. Sofroniew, Eric R. Kandel, and René Hen Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4642–4646. Published online 2007 March 5. doi: 10.1073/pnas.0611718104.PMCID: PMC1810330 VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants Jennifer L. Warner-Schmidt and Ronald S. Duman Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4647–4652. Published online 2007 March 5. doi: 10.1073/pnas.0610282104.PMCID: PMC1838655 GSK-3/Shaggy regulates olfactory habituation in Drosophila Fred W. Wolf, Mark Eddison, Seonok Lee, William Cho, and Ulrike Heberlein Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4653–4657. Published online 2007 March 6. doi: 10.1073/pnas.0700493104.PMCID: PMC1838656 Network activity-independent coordinated gene expression program for synapse assembly Luis M. Valor, Paul Charlesworth, Lawrence Humphreys, Chris N. G. Anderson, and Seth G. N. Grant Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4658–4663. Published online 2007 March 5. doi: 10.1073/pnas.0609071104.PMCID: PMC1810326 From the Cover: Pleiotrophin is a neurotrophic factor for spinal motor neurons Ruifa Mi, Weiran Chen, and Ahmet Höke Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4664–4669. Published online 2007 March 5. doi: 10.1073/pnas.0603243104.PMCID: PMC1838658 Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice Elena Choleris, Steven R. Little, Jessica A. Mong, Sidharth V. Puram, Robert Langer, and Donald W. Pfaff Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4670–4675. Published online 2007 March 5. doi: 10.1073/pnas.0700670104.PMCID: PMC1838659 Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters E. Dong, A. Guidotti, D. R. Grayson, and E. Costa Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4676–4681. Published online 2007 March 7. doi: 10.1073/pnas.0700529104.PMCID: PMC1815468 Orai proteins interact with TRPC channels and confer responsiveness to store depletion Yanhong Liao, Christian Erxleben, Eda Yildirim, Joel Abramowitz, David L. Armstrong, and Lutz Birnbaumer Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4682–4687. Published online 2007 March 7. doi: 10.1073/pnas.0611692104.PMCID: PMC1838661 Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice Aaron M. Rozeboom, Huda Akil, and Audrey F. Seasholtz Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4688–4693. Published online 2007 March 5. doi: 10.1073/pnas.0606067104.PMCID: PMC1838662 TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity Krisztián A. Kovács, Pascal Steullet, Myriam Steinmann, Kim Q. Do, Pierre J. Magistretti, Olivier Halfon, and Jean-René Cardinaux Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4700–4705. Published online 2007 March 6. doi: 10.1073/pnas.0607524104.PMCID: PMC1838663 Modulation of Drosophila male behavioral choice Sarah J. Certel, Mary Grace Savella, Dana C. F. Schlegel, and Edward A. Kravitz Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4706–4711. Published online 2007 March 5. doi: 10.1073/pnas.0700328104.PMCID: PMC1810337 Accumulation of prion protein in the brain that is not associated with transmissible disease Pedro Piccardo, Jean C. Manson, Declan King, Bernardino Ghetti, and Rona M. Barron Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4712–4717. Published online 2007 March 6. doi: 10.1073/pnas.0609241104.PMCID: PMC1838665 Physiology Scaling of number, size, and metabolic rate of cells with body size in mammals Van M. Savage, Andrew P. Allen, James H. Brown, James F. Gillooly, Alexander B. Herman, William H. Woodruff, and Geoffrey B. West Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4718–4723. Published online 2007 March 1. doi: 10.1073/pnas.0611235104.PMCID: PMC1838666 Plant Biology From the Cover: A gene essential for hydrotropism in roots Akie Kobayashi, Akiko Takahashi, Yoko Kakimoto, Yutaka Miyazawa, Nobuharu Fujii, Atsushi Higashitani, and Hideyuki Takahashi Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4724–4729. Published online 2007 March 5. doi: 10.1073/pnas.0609929104.PMCID: PMC1810325 Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays Sorina C. Popescu, George V. Popescu, Shawn Bachan, Zimei Zhang, Montrell Seay, Mark Gerstein, Michael Snyder, and S. P. Dinesh-Kumar Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4730–4735. Published online 2007 February 23. doi: 10.1073/pnas.0611615104.PMCID: PMC1838668 WD40 protein Mda1 is purified with Dnm1 and forms a dividing ring for mitochondria before Dnm1 in Cyanidioschyzon merolae Keiji Nishida, Fumi Yagisawa, Haruko Kuroiwa, Yamato Yoshida, and Tsuneyoshi Kuroiwa Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4736–4741. Published online 2007 March 1. doi: 10.1073/pnas.0609364104.PMCID: PMC1838669 Modulating seed β-ketoacyl-acyl carrier protein synthase II level converts the composition of a temperate seed oil to that of a palm-like tropical oil Mark S. Pidkowich, Huu Tam Nguyen, Ingo Heilmann, Till Ischebeck, and John Shanklin Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4742–4747. Published online 2007 March 5. doi: 10.1073/pnas.0611141104.PMCID: PMC1838670 The metabolic signature related to high plant growth rate in Arabidopsis thaliana Rhonda C. Meyer, Matthias Steinfath, Jan Lisec, Martina Becher, Hanna Witucka-Wall, Ottó Törjék, Oliver Fiehn, Änne Eckardt, Lothar Willmitzer, Joachim Selbig, and Thomas Altmann Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4759–4764. Published online 2007 March 5. doi: 10.1073/pnas.0609709104.PMCID: PMC1810331 Population Biology A population genetics model with recombination hotspots that are heterogeneous across the population Peter Calabrese Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4748–4752. Published online 2007 March 5. doi: 10.1073/pnas.0610195104.PMCID: PMC1838671 Psychology Developmental vision determines the reference frame for the multisensory control of action Brigitte Röder, Anna Kusmierek, Charles Spence, and Tobias Schicke Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4753–4758. Published online 2007 March 7. doi: 10.1073/pnas.0607158104.PMCID: PMC1838672 Sustainability Science The metabolic signature related to high plant growth rate in Arabidopsis thaliana Rhonda C. Meyer, Matthias Steinfath, Jan Lisec, Martina Becher, Hanna Witucka-Wall, Ottó Törjék, Oliver Fiehn, Änne Eckardt, Lothar Willmitzer, Joachim Selbig, and Thomas Altmann Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4759–4764. Published online 2007 March 5. doi: 10.1073/pnas.0609709104.PMCID: PMC1810331 Social Sciences Anthropology Nonlinear scaling of space use in human hunter–gatherers Marcus J. Hamilton, Bruce T. Milne, Robert S. Walker, and James H. Brown Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4765–4769. Published online 2007 March 6. doi: 10.1073/pnas.0611197104.PMCID: PMC1810510 Correction Correction for Huang et al., A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection Proc Natl Acad Sci U S A. 2007 March 13; 104(11): 4770. Published online 2007 February 28. doi: 10.1073/pnas.0701153104.PMCID: PMC1838675 Corrects: Ying Huang, et al. A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection. Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 985–990. |