pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 102(51);  December 20, 2005
In This Issue
This Week in PNAS
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18243–18244. doi: 10.1073/iti5105102.
PMCID: PMC1317898
Commentaries
When the B-team runs plasticity: GluR2 receptor trafficking in cerebellar long-term potentiation
Christian Hansel
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18245–18246. Published online 2005 December 12. doi: 10.1073/pnas.0509686102.
PMCID: PMC1317989
The chemistry of child neglect: Do oxytocin and vasopressin mediate the effects of early experience?
C. Sue Carter
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18247–18248. Published online 2005 December 12. doi: 10.1073/pnas.0509376102.
PMCID: PMC1317979
Profile
Profile of Raymond C. Kelly
Nick Zagorski
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18249–18251. Published online 2005 December 13. doi: 10.1073/pnas.0506968102.
PMCID: PMC1317930
Physical Sciences
Applied Physical Sciences
Volumetric tomography of fluorescent proteins through small animals in vivo
Giannis Zacharakis, Hirokazu Kambara, Helen Shih, Jorge Ripoll, Jan Grimm, Yoshinaga Saeki, Ralph Weissleder, and Vasilis Ntziachristos
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18252–18257. Published online 2005 December 12. doi: 10.1073/pnas.0504628102.
PMCID: PMC1317905
Solvent and mutation effects on the nucleation of amyloid β-protein folding
Luis Cruz, Brigita Urbanc, Jose M. Borreguero, Noel D. Lazo, David B. Teplow, and H. Eugene Stanley
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18258–18263. Published online 2005 December 9. doi: 10.1073/pnas.0509276102.
PMCID: PMC1317965
Chemistry
In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles
Young Jik Kwon, Edward James, Nilabh Shastri, and Jean M. J. Fréchet
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18264–18268. Published online 2005 December 12. doi: 10.1073/pnas.0509541102.
PMCID: PMC1317987
Controlling ligand substitution reactions of organometallic complexes: Tuning cancer cell cytotoxicity
Fuyi Wang, Abraha Habtemariam, Erwin P. L. van der Geer, Rafael Fernández, Michael Melchart, Robert J. Deeth, Rhona Aird, Sylvie Guichard, Francesca P. A. Fabbiani, Patricia Lozano-Casal, Iain D. H. Oswald, Duncan I. Jodrell, Simon Parsons, and Peter J. Sadler
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18269–18274. Published online 2005 December 13. doi: 10.1073/pnas.0505798102.
PMCID: PMC1317918
Hyperpolarized krypton-83 as a contrast agent for magnetic resonance imaging
Galina E. Pavlovskaya, Zackary I. Cleveland, Karl F. Stupic, Randall J. Basaraba, and Thomas Meersmann
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18275–18279. Published online 2005 December 12. doi: 10.1073/pnas.0509419102.
PMCID: PMC1317982
Modulation of the electronic structure and the Ni–Fe distance in heterobimetallic models for the active site in [NiFe]hydrogenase
Wenfeng Zhu, Andrew C. Marr, Qiang Wang, Frank Neese, Douglas J. E. Spencer, Alexander J. Blake, Paul A. Cooke, Claire Wilson, and Martin Schröder
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18280–18285. Published online 2005 December 13. doi: 10.1073/pnas.0505779102.
PMCID: PMC1317917
Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method
Hiroaki Gouda, Toshiaki Sunazuka, Hideaki Ui, Masaki Handa, Yusuke Sakoh, Yuzuru Iwai, Shuichi Hirono, and Satoshi Ōmura
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18286–18291. Published online 2005 December 12. doi: 10.1073/pnas.0508425102.
PMCID: PMC1317948
Environmental Sciences
Microbial origin of excess methane in glacial ice and implications for life on Mars
H. C. Tung, N. E. Bramall, and P. B. Price
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18292–18296. Published online 2005 December 7. doi: 10.1073/pnas.0507601102.
PMCID: PMC1308353
Geophysics
Microbial origin of excess methane in glacial ice and implications for life on Mars
H. C. Tung, N. E. Bramall, and P. B. Price
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18292–18296. Published online 2005 December 7. doi: 10.1073/pnas.0507601102.
PMCID: PMC1308353
Statistics
Information-based clustering
Noam Slonim, Gurinder Singh Atwal, Gašper Tkačik, and William Bialek
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18297–18302. Published online 2005 December 13. doi: 10.1073/pnas.0507432102.
PMCID: PMC1317937
Biological Sciences
Agricultural Sciences
Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor
Claudia Pérez, Luisa E. Fernandez, Jianguang Sun, Jorge Luis Folch, Sarjeet S. Gill, Mario Soberón, and Alejandra Bravo
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18303–18308. Published online 2005 December 9. doi: 10.1073/pnas.0505494102.
PMCID: PMC1317914
Anthropology
Cranial morphology of early Americans from Lagoa Santa, Brazil: Implications for the settlement of the New World
Walter A. Neves and Mark Hubbe
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18309–18314. Published online 2005 December 12. doi: 10.1073/pnas.0507185102.
PMCID: PMC1317934
An Asian origin for a 10,000-year-old domesticated plant in the Americas
David L. Erickson, Bruce D. Smith, Andrew C. Clarke, Daniel H. Sandweiss, and Noreen Tuross
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18315–18320. Published online 2005 December 13. doi: 10.1073/pnas.0509279102.
PMCID: PMC1311910
Applied Biological Sciences
From the Cover:
Generating highly ordered DNA nanostrand arrays
Jingjiao Guan and L. James Lee
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18321–18325. Published online 2005 December 13. doi: 10.1073/pnas.0506902102.
PMCID: PMC1317928
Biochemistry
The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation
Michael Sacher, Alessandra Di Bacco, Vladimir V. Lunin, Zheng Ye, John Wagner, Grace Gill, and Miroslaw Cygler
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18326–18331. Published online 2005 December 12. doi: 10.1073/pnas.0505071102.
PMCID: PMC1317909
Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design
Mi Li, Gary S. Laco, Mariusz Jaskolski, Jan Rozycki, Jerry Alexandratos, Alexander Wlodawer, and Alla Gustchina
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18332–18337. Published online 2005 December 13. doi: 10.1073/pnas.0509335102.
PMCID: PMC1317974
The tethered motor domain of a kinesin-microtubule complex catalyzes reversible synthesis of bound ATP
David D. Hackney
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18338–18343. Published online 2005 December 9. doi: 10.1073/pnas.0505288102.
PMCID: PMC1317912
Sequence determinants of a conformational switch in a protein structure
Thomas A. Anderson, Matthew H. J. Cordes, and Robert T. Sauer
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18344–18349. Published online 2005 December 12. doi: 10.1073/pnas.0509349102.
PMCID: PMC1317976
Human La is found at RNA polymerase III-transcribed genes in vivo
Jennifer A. Fairley, Theodoros Kantidakis, Niall S. Kenneth, Robert V. Intine, Richard J. Maraia, and Robert J. White
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18350–18355. Published online 2005 December 12. doi: 10.1073/pnas.0506415102.
PMCID: PMC1317925
The proficiency of a thermophilic chorismate mutase enzyme is solely through an entropic advantage in the enzyme reaction
Xiaohua Zhang and Thomas C. Bruice
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18356–18360. Published online 2005 December 12. doi: 10.1073/pnas.0509234102.
PMCID: PMC1317962
Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases η and REV1
Parie Garg and Peter M. Burgers
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18361–18366. Published online 2005 December 12. doi: 10.1073/pnas.0505949102.
PMCID: PMC1317920
Introduction of an additional pathway for lactate oxidation in the treatment of lactic acidosis and mitochondrial dysfunction in Caenorhabditis elegans
Leslie I. Grad, Leanne C. Sayles, and Bernard D. Lemire
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18367–18372. Published online 2005 December 12. doi: 10.1073/pnas.0506939102.
PMCID: PMC1311736
Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A
Jason G. S. Ho, Antonio Greco, Maja Rupnik, and Kenneth K.-S. Ng
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18373–18378. Published online 2005 December 12. doi: 10.1073/pnas.0506391102.
PMCID: PMC1317924
Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein
Jin-Shan Hu, Hanqiao Feng, Wangyong Zeng, Guang-xin Lin, and Xu Guang Xi
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18379–18384. Published online 2005 December 9. doi: 10.1073/pnas.0509380102.
PMCID: PMC1317980
Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling
Bing Li, Samantha G. Pattenden, Daeyoup Lee, José Gutiérrez, Jie Chen, Chris Seidel, Jennifer Gerton, and Jerry L. Workman
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18385–18390. Published online 2005 December 12. doi: 10.1073/pnas.0507975102.
PMCID: PMC1317944
Biophysics
Solvent and mutation effects on the nucleation of amyloid β-protein folding
Luis Cruz, Brigita Urbanc, Jose M. Borreguero, Noel D. Lazo, David B. Teplow, and H. Eugene Stanley
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18258–18263. Published online 2005 December 9. doi: 10.1073/pnas.0509276102.
PMCID: PMC1317965
Structure of the streptococcal cell wall C5a peptidase
C. Kent Brown, Zu-Yi Gu, Yury V. Matsuka, Sai S. Purushothaman, Laurie A. Winter, P. Patrick Cleary, Stephen B. Olmsted, Douglas H. Ohlendorf, and Cathleen A. Earhart
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18391–18396. Published online 2005 December 12. doi: 10.1073/pnas.0504954102.
PMCID: PMC1317908
Snapshots of cytochrome c folding
Ekaterina V. Pletneva, Harry B. Gray, and Jay R. Winkler
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18397–18402. Published online 2005 December 12. doi: 10.1073/pnas.0509076102.
PMCID: PMC1317956
Diffusion and scaling during early embryonic pattern formation
Thomas Gregor, William Bialek, Rob R. de Ruyter van Steveninck, David W. Tank, and Eric F. Wieschaus
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18403–18407. Published online 2005 December 13. doi: 10.1073/pnas.0509483102.
PMCID: PMC1311912
Mechanism of metal ion activation of the diphtheria toxin repressor DtxR
J. Alejandro D'Aquino, Jaclyn Tetenbaum-Novatt, Andre White, Fred Berkovitch, and Dagmar Ringe
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18408–18413. Published online 2005 December 13. doi: 10.1073/pnas.0500908102.
PMCID: PMC1317899
Topology of biological networks and reliability of information processing
Konstantin Klemm and Stefan Bornholdt
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18414–18419. Published online 2005 December 8. doi: 10.1073/pnas.0509132102.
PMCID: PMC1317958
Cell Biology
An antiviral role for the RNA interference machinery in Caenorhabditis elegans
Daniel H. Schott, David K. Cureton, Sean P. Whelan, and Craig P. Hunter
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18420–18424. Published online 2005 December 9. doi: 10.1073/pnas.0507123102.
PMCID: PMC1317933
Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes
Gabrielle G. M. Pinkse, Odette H. M. Tysma, Cees A. M. Bergen, Michel G. D. Kester, Ferry Ossendorp, Peter A. van Veelen, Bart Keymeulen, Danny Pipeleers, Jan W. Drijfhout, and Bart O. Roep
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18425–18430. Published online 2005 December 9. doi: 10.1073/pnas.0508621102.
PMCID: PMC1317949
Up-regulation of β-catenin by a viral oncogene correlates with inhibition of the seven in absentia homolog 1 in B lymphoma cells
Kyung Lib Jang, Julia Shackelford, So Young Seo, and Joseph S. Pagano
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18431–18436. Published online 2005 December 12. doi: 10.1073/pnas.0504054102.
PMCID: PMC1317901
Differential cis-regulation of human versus mouse TERT gene expression in vivo: Identification of a human-specific repressive element
Izumi Horikawa, Y. Jeffrey Chiang, Tricia Patterson, Lionel Feigenbaum, Sun-Hee Leem, Eriko Michishita, Vladimir Larionov, Richard J. Hodes, and J. Carl Barrett
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18437–18442. Published online 2005 December 12. doi: 10.1073/pnas.0508964102.
PMCID: PMC1317953
The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells
Jean J. Zhao, Zhenning Liu, Li Wang, Eyoung Shin, Massimo F. Loda, and Thomas M. Roberts
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18443–18448. Published online 2005 December 8. doi: 10.1073/pnas.0508988102.
PMCID: PMC1317954
Targeted ablation of plectin isoform 1 uncovers role of cytolinker proteins in leukocyte recruitment
Christina Abrahamsberg, Peter Fuchs, Selma Osmanagic-Myers, Irmgard Fischer, Friedrich Propst, Adelheid Elbe-Bürger, and Gerhard Wiche
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18449–18454. Published online 2005 December 12. doi: 10.1073/pnas.0505380102.
PMCID: PMC1317913
Developmental Biology
From the Cover:
Epicardial retinoid X receptor α is required for myocardial growth and coronary artery formation
Esther Merki, Mónica Zamora, Angel Raya, Yasuhiko Kawakami, Jianming Wang, Xiaoxue Zhang, John Burch, Steven W. Kubalak, Perla Kaliman, Juan Carlos Izpisua Belmonte, Kenneth R. Chien, and Pilar Ruiz-Lozano
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18455–18460. Published online 2005 December 13. doi: 10.1073/pnas.0504343102.
PMCID: PMC1317903
Two types of precursor cells in a multipotential hematopoietic cell line
Zhi-jia Ye, Yuval Kluger, Zheng Lian, and Sherman M. Weissman
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18461–18466. Published online 2005 December 13. doi: 10.1073/pnas.0509314102.
PMCID: PMC1317970
Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis
Soojin Ryu, Jochen Holzschuh, Simone Erhardt, Anne-Kathrin Ettl, and Wolfgang Driever
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18467–18472. Published online 2005 December 8. doi: 10.1073/pnas.0506187102.
PMCID: PMC1317923
The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney
Sung-Kook Hong, Caroline E. Haldin, Nathan D. Lawson, Brant M. Weinstein, Igor B. Dawid, and Neil A. Hukriede
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18473–18478. Published online 2005 December 12. doi: 10.1073/pnas.0509457102.
PMCID: PMC1311743
Mapping Dmef2-binding regulatory modules by using a ChIP-enriched in silico targets approach
Guillaume Junion, Teresa Jagla, Sebastien Duplant, Romain Tapin, Jean-Philippe Da Ponte, and Krzysztof Jagla
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18479–18484. Published online 2005 December 9. doi: 10.1073/pnas.0507030102.
PMCID: PMC1317932
A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells
Asim S. Siddiqui, Jaswinder Khattra, Allen D. Delaney, Yongjun Zhao, Caroline Astell, Jennifer Asano, Ryan Babakaiff, Sarah Barber, Jaclyn Beland, Slavita Bohacec, Mabel Brown-John, Steve Chand, David Charest, Anita M. Charters, Rebecca Cullum, Noreen Dhalla, Ruth Featherstone, Daniela S. Gerhard, Brad Hoffman, Robert A. Holt, Juan Hou, Byron Y.-L. Kuo, Lisa L. C. Lee, Stephanie Lee, Derek Leung, Kevin Ma, Corey Matsuo, Michael Mayo, Helen McDonald, Anna-liisa Prabhu, Pawan Pandoh, Gregory J. Riggins, Teresa Ruiz de Algara, James L. Rupert, Duane Smailus, Jeff Stott, Miranda Tsai, Richard Varhol, Pavle Vrljicak, David Wong, Mona K. Wu, Yuan-Yun Xie, George Yang, Ida Zhang, Martin Hirst, Steven J. M. Jones, Cheryl D. Helgason, Elizabeth M. Simpson, Pamela A. Hoodless, and Marco A. Marra
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18485–18490. Published online 2005 December 13. doi: 10.1073/pnas.0509455102.
PMCID: PMC1311911
The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: Analysis of ESTs from the hermaphroditic strain
Ricardo M. Zayas, Alvaro Hernández, Bianca Habermann, Yuying Wang, Joel M. Stary, and Phillip A. Newmark
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18491–18496. Published online 2005 December 12. doi: 10.1073/pnas.0509507102.
PMCID: PMC1317986
Ecology
Pinpointing and preventing imminent extinctions
Taylor H. Ricketts, Eric Dinerstein, Tim Boucher, Thomas M. Brooks, Stuart H. M. Butchart, Michael Hoffmann, John F. Lamoreux, John Morrison, Mike Parr, John D. Pilgrim, Ana S. L. Rodrigues, Wes Sechrest, George E. Wallace, Ken Berlin, Jon Bielby, Neil D. Burgess, Don R. Church, Neil Cox, David Knox, Colby Loucks, Gary W. Luck, Lawrence L. Master, Robin Moore, Robin Naidoo, Robert Ridgely, George E. Schatz, Gavin Shire, Holly Strand, Wes Wettengel, and Eric Wikramanayake
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18497–18501. Published online 2005 December 12. doi: 10.1073/pnas.0509060102.
PMCID: PMC1311739
Slow growth rates of Amazonian trees: Consequences for carbon cycling
Simone Vieira, Susan Trumbore, Plinio B. Camargo, Diogo Selhorst, Jeffrey Q. Chambers, Niro Higuchi, and Luiz Antonio Martinelli
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18502–18507. Published online 2005 December 9. doi: 10.1073/pnas.0505966102.
PMCID: PMC1310511
Evolution
Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes
Benjamin F. Voight, Alison M. Adams, Linda A. Frisse, Yudong Qian, Richard R. Hudson, and Anna Di Rienzo
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18508–18513. Published online 2005 December 13. doi: 10.1073/pnas.0507325102.
PMCID: PMC1311907
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection
Simon D. W. Frost, Terri Wrin, Davey M. Smith, Sergei L. Kosakovsky Pond, Yang Liu, Ellen Paxinos, Colombe Chappey, Justin Galovich, Jeff Beauchaine, Christos J. Petropoulos, Susan J. Little, and Douglas D. Richman
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18514–18519. Published online 2005 December 9. doi: 10.1073/pnas.0504658102.
PMCID: PMC1310509
Genetics
Interaction of nephrocystin-4 and RPGRIP1 is disrupted by nephronophthisis or Leber congenital amaurosis-associated mutations
Ronald Roepman, Stef J. F. Letteboer, Heleen H. Arts, Sylvia E. C. van Beersum, Xinrong Lu, Elmar Krieger, Paulo A. Ferreira, and Frans P. M. Cremers
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18520–18525. Published online 2005 December 9. doi: 10.1073/pnas.0505774102.
PMCID: PMC1317916
A high-resolution whole-genome cattle–human comparative map reveals details of mammalian chromosome evolution
Annelie Everts-van der Wind, Denis M. Larkin, Cheryl A. Green, Janice S. Elliott, Colleen A. Olmstead, Readman Chiu, Jacqueline E. Schein, Marco A. Marra, James E. Womack, and Harris A. Lewin
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18526–18531. Published online 2005 December 9. doi: 10.1073/pnas.0509285102.
PMCID: PMC1317968
Immunology
Notch deficiency implicated in the pathogenesis of congenital disorder of glycosylation IIc
Hiroyuki O. Ishikawa, Shunsuke Higashi, Tomonori Ayukawa, Takeshi Sasamura, Motoo Kitagawa, Kenichi Harigaya, Kazuhisa Aoki, Nobuhiro Ishida, Yutaka Sanai, and Kenji Matsuno
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18532–18537. Published online 2005 December 12. doi: 10.1073/pnas.0504115102.
PMCID: PMC1317902
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
Eiichi Sato, Sara H. Olson, Jiyoung Ahn, Brian Bundy, Hiroyoshi Nishikawa, Feng Qian, Achim A. Jungbluth, Denise Frosina, Sacha Gnjatic, Christine Ambrosone, James Kepner, Tosin Odunsi, Gerd Ritter, Shashikant Lele, Yao-Tseng Chen, Haruo Ohtani, Lloyd J. Old, and Kunle Odunsi
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18538–18543. Published online 2005 December 12. doi: 10.1073/pnas.0509182102.
PMCID: PMC1311741
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
Domenico Rosa, Giulietta Saletti, Ennio De Gregorio, Francesca Zorat, Consuelo Comar, Ugo D'Oro, Sandra Nuti, Michael Houghton, Vincenzo Barnaba, Gabriele Pozzato, and Sergio Abrignani
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18544–18549. Published online 2005 December 9. doi: 10.1073/pnas.0509402102.
PMCID: PMC1310512
Social relationships, sleep quality, and interleukin-6 in aging women
Elliot M. Friedman, Mary S. Hayney, Gayle D. Love, Heather L. Urry, Melissa A. Rosenkranz, Richard J. Davidson, Burton H. Singer, and Carol D. Ryff
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18757–18762. Published online 2005 December 8. doi: 10.1073/pnas.0509281102.
PMCID: PMC1317967
Medical Sciences
Three independent biological mechanisms cause exercise-associated hyponatremia: Evidence from 2,135 weighed competitive athletic performances
T. D. Noakes, K. Sharwood, D. Speedy, T. Hew, S. Reid, J. Dugas, C. Almond, P. Wharam, and L. Weschler
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18550–18555. Published online 2005 December 12. doi: 10.1073/pnas.0509096102.
PMCID: PMC1311740
Human cancers overexpress genes that are specific to a variety of normal human tissues
Joseph Lotem, Dvir Netanely, Eytan Domany, and Leo Sachs
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18556–18561. Published online 2005 December 8. doi: 10.1073/pnas.0509360102.
PMCID: PMC1317977
Epstein–Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase
Jason S. Knight, Nikhil Sharma, and Erle S. Robertson
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18562–18566. Published online 2005 December 13. doi: 10.1073/pnas.0503886102.
PMCID: PMC1317900
Repression of β-catenin function in malignant cells by nonsteroidal antiinflammatory drugs
Desheng Lu, Howard B. Cottam, Maripat Corr, and Dennis A. Carson
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18567–18571. Published online 2005 December 13. doi: 10.1073/pnas.0509316102.
PMCID: PMC1317972
Microbiology
Poxvirus multiprotein entry–fusion complex
Tatiana G. Senkevich, Suany Ojeda, Alan Townsley, Gretchen E. Nelson, and Bernard Moss
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18572–18577. Published online 2005 December 8. doi: 10.1073/pnas.0509239102.
PMCID: PMC1309049
Bordetella filamentous hemagglutinin plays a critical role in immunomodulation, suggesting a mechanism for host specificity
Carol S. Inatsuka, Steven M. Julio, and Peggy A. Cotter
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18578–18583. Published online 2005 December 9. doi: 10.1073/pnas.0507910102.
PMCID: PMC1317942
Posttranslational conversion of l-serines to d-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147
Paul D. Cotter, Paula M. O'Connor, Lorraine A. Draper, Elaine M. Lawton, Lucy H. Deegan, Colin Hill, and R. Paul Ross
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18584–18589. Published online 2005 December 8. doi: 10.1073/pnas.0509371102.
PMCID: PMC1317978
The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host
G. Gabriel, B. Dauber, T. Wolff, O. Planz, H.-D. Klenk, and J. Stech
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18590–18595. Published online 2005 December 8. doi: 10.1073/pnas.0507415102.
PMCID: PMC1317936
Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis
Ke Shi, C. Kent Brown, Zu-Yi Gu, Briana K. Kozlowicz, Gary M. Dunny, Douglas H. Ohlendorf, and Cathleen A. Earhart
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18596–18601. Published online 2005 December 8. doi: 10.1073/pnas.0506163102.
PMCID: PMC1317922
The cell-shape protein MreC interacts with extracytoplasmic proteins including cell wall assembly complexes in Caulobacter crescentus
Arun V. Divakaruni, Rachel R. Ogorzalek Loo, Yongming Xie, Joseph A. Loo, and James W. Gober
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18602–18607. Published online 2005 December 12. doi: 10.1073/pnas.0507937102.
PMCID: PMC1317943
Two independent spiral structures control cell shape in Caulobacter
Natalie A. Dye, Zachary Pincus, Julie A. Theriot, Lucy Shapiro, and Zemer Gitai
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18608–18613. Published online 2005 December 12. doi: 10.1073/pnas.0507708102.
PMCID: PMC1317941
Neuroscience
Unexceptional sharpness of frequency tuning in the human cochlea
Mario A. Ruggero and Andrei N. Temchin
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18614–18619. Published online 2005 December 12. doi: 10.1073/pnas.0509323102.
PMCID: PMC1311742
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
G. Gobbi, F. R. Bambico, R. Mangieri, M. Bortolato, P. Campolongo, M. Solinas, T. Cassano, M. G. Morgese, G. Debonnel, A. Duranti, A. Tontini, G. Tarzia, M. Mor, V. Trezza, S. R. Goldberg, V. Cuomo, and D. Piomelli
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18620–18625. Published online 2005 December 13. doi: 10.1073/pnas.0509591102.
PMCID: PMC1317988
Control over brain activation and pain learned by using real-time functional MRI
R. Christopher deCharms, Fumiko Maeda, Gary H. Glover, David Ludlow, John M. Pauly, Deepak Soneji, John D. E. Gabrieli, and Sean C. Mackey
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18626–18631. Published online 2005 December 13. doi: 10.1073/pnas.0505210102.
PMCID: PMC1311906
Modulation of neuropeptide Y expression in adult mice does not affect feeding
Linda Ste. Marie, Serge Luquet, Toby B. Cole, and Richard D. Palmiter
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18632–18637. Published online 2005 December 8. doi: 10.1073/pnas.0509240102.
PMCID: PMC1309050
Inhibitory coupling specifically generates emergent gamma oscillations in diverse cell types
Vikaas S. Sohal and John R. Huguenard
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18638–18643. Published online 2005 December 8. doi: 10.1073/pnas.0509291102.
PMCID: PMC1317969
Development of functional human embryonic stem cell-derived neurons in mouse brain
Alysson R. Muotri, Kinichi Nakashima, Nicolas Toni, Vladislav M. Sandler, and Fred H. Gage
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18644–18648. Published online 2005 December 13. doi: 10.1073/pnas.0509315102.
PMCID: PMC1317971
The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal
Angelo Contarino and Francesco Papaleo
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18649–18654. Published online 2005 December 8. doi: 10.1073/pnas.0506999102.
PMCID: PMC1317931
Neurons of the cerebral cortex exhibit precise interspike timing in correspondence to behavior
Tomer Shmiel, Rotem Drori, Oren Shmiel, Yoram Ben-Shaul, Zoltan Nadasdy, Moshe Shemesh, Mina Teicher, and Moshe Abeles
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18655–18657. Published online 2005 December 9. doi: 10.1073/pnas.0509346102.
PMCID: PMC1317975
Recombinant human nerve growth factor with a marked activity in vitro and in vivo
Anna M. Colangelo, Nicoletta Finotti, Michela Ceriani, Lilia Alberghina, Enzo Martegani, Luigi Aloe, Laura Lenzi, and Rita Levi-Montalcini
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18658–18663. Published online 2005 December 8. doi: 10.1073/pnas.0508734102.
PMCID: PMC1317951
Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1
J.-S. Rhee, L. Y. Li, O.-H. Shin, J.-C. Rah, J. Rizo, T. C. Südhof, and C. Rosenmund
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18664–18669. Published online 2005 December 13. doi: 10.1073/pnas.0509153102.
PMCID: PMC1311909
From the Cover:
Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice
Yoichi Kondo, David A. Wenger, Vittorio Gallo, and Ian D. Duncan
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18670–18675. Published online 2005 December 13. doi: 10.1073/pnas.0506473102.
PMCID: PMC1317926
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
Wanli W. Smith, Zhong Pei, Haibing Jiang, Darren J. Moore, Yideng Liang, Andrew B. West, Valina L. Dawson, Ted M. Dawson, and Christopher A. Ross
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18676–18681. Published online 2005 December 13. doi: 10.1073/pnas.0508052102.
PMCID: PMC1317945
Unconscious fear influences emotional awareness of faces and voices
B. de Gelder, J. S. Morris, and R. J. Dolan
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18682–18687. Published online 2005 December 13. doi: 10.1073/pnas.0509179102.
PMCID: PMC1317960
Beyond the olfactory bulb: An odotopic map in the forebrain
Alexander A. Nikonov, Thomas E. Finger, and John Caprio
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18688–18693. Published online 2005 December 7. doi: 10.1073/pnas.0505241102.
PMCID: PMC1317911
Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity
Shengjun Chang, Tian ran Ma, R. Dennis Miranda, Maureen E. Balestra, Robert W. Mahley, and Yadong Huang
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18694–18699. Published online 2005 December 12. doi: 10.1073/pnas.0508254102.
PMCID: PMC1311737
Apolipoprotein (apo) E4 enhances amyloid β peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target
Shiming Ye, Yadong Huang, Karin Müllendorff, Liming Dong, Gretchen Giedt, Elaine C. Meng, Fred E. Cohen, Irwin D. Kuntz, Karl H. Weisgraber, and Robert W. Mahley
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18700–18705. Published online 2005 December 12. doi: 10.1073/pnas.0508693102.
PMCID: PMC1311738
Pharmacology
Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells
Muriel Nobles, Amy Benians, and Andrew Tinker
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18706–18711. Published online 2005 December 13. doi: 10.1073/pnas.0504778102.
PMCID: PMC1317907
From the Cover:
A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo
Kayo Mitsukawa, Rina Yamamoto, Silvio Ofner, Joachim Nozulak, Oliver Pescott, Snezana Lukic, Natacha Stoehr, Cedric Mombereau, Rainer Kuhn, Kevin H. McAllister, Herman van der Putten, John F. Cryan, and Peter J. Flor
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18712–18717. Published online 2005 December 9. doi: 10.1073/pnas.0508063102.
PMCID: PMC1317946
Physiology
Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor
John P. A. Bannister, Baron Chanda, Francisco Bezanilla, and Diane M. Papazian
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18718–18723. Published online 2005 December 9. doi: 10.1073/pnas.0505766102.
PMCID: PMC1317915
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
Hong-Bo Zhao, Ning Yu, and Carrie R. Fleming
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18724–18729. Published online 2005 December 12. doi: 10.1073/pnas.0506481102.
PMCID: PMC1317927
Plant Biology
A regulator of nutritional copper signaling in Chlamydomonas is an SBP domain protein that recognizes the GTAC core of copper response element
Janette Kropat, Stephen Tottey, Rainer P. Birkenbihl, Nathalie Depège, Peter Huijser, and Sabeeha Merchant
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18730–18735. Published online 2005 December 13. doi: 10.1073/pnas.0507693102.
PMCID: PMC1311908
RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth
Keiko Sugimoto-Shirasu, Gethin R. Roberts, Nicola J. Stacey, Maureen C. McCann, Anthony Maxwell, and Keith Roberts
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18736–18741. Published online 2005 December 8. doi: 10.1073/pnas.0505883102.
PMCID: PMC1309048
From the Cover:
Shoot circumnutation and winding movements require gravisensing cells
Daisuke Kitazawa, Yasuko Hatakeda, Motoshi Kamada, Nobuharu Fujii, Yutaka Miyazawa, Atsushi Hoshino, Shigeru Iida, Hidehiro Fukaki, Miyo Terao Morita, Masao Tasaka, Hiroshi Suge, and Hideyuki Takahashi
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18742–18747. Published online 2005 December 9. doi: 10.1073/pnas.0504617102.
PMCID: PMC1310508
Psychology
Auditory-visual fusion in speech perception in children with cochlear implants
Efrat A. Schorr, Nathan A. Fox, Virginie van Wassenhove, and Eric I. Knudsen
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18748–18750. Published online 2005 December 8. doi: 10.1073/pnas.0508862102.
PMCID: PMC1317952
The spread of attention across modalities and space in a multisensory object
Laura Busse, Kenneth C. Roberts, Roy E. Crist, Daniel H. Weissman, and Marty G. Woldorff
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18751–18756. Published online 2005 December 9. doi: 10.1073/pnas.0507704102.
PMCID: PMC1317940
Social Sciences
Anthropology
An Asian origin for a 10,000-year-old domesticated plant in the Americas
David L. Erickson, Bruce D. Smith, Andrew C. Clarke, Daniel H. Sandweiss, and Noreen Tuross
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18315–18320. Published online 2005 December 13. doi: 10.1073/pnas.0509279102.
PMCID: PMC1311910
Psychology
Social relationships, sleep quality, and interleukin-6 in aging women
Elliot M. Friedman, Mary S. Hayney, Gayle D. Love, Heather L. Urry, Melissa A. Rosenkranz, Richard J. Davidson, Burton H. Singer, and Carol D. Ryff
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18757–18762. Published online 2005 December 8. doi: 10.1073/pnas.0509281102.
PMCID: PMC1317967
Corrections
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18763. Published online 2005 December 7. doi: 10.1073/pnas.0509848102.
PMCID: PMC1317990
Corrects: A. Bilkei-Gorzo, et al. Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. Proc Natl Acad Sci U S A. 2005 October 25; 102(43): 15670–15675.
Proc Natl Acad Sci U S A. 2005 December 20; 102(51): 18763. Published online 2005 December 7. doi: 10.1073/pnas.0509997102.
PMCID: PMC1317991
Corrects: Haiying Meng, et al. From the Cover:
DCDC2 is associated with reading disability and modulates neuronal development in the brain.
Proc Natl Acad Sci U S A. 2005 November 22; 102(47): 17053–17058.
Other Issues:  previous | next | latest | archive