| | This journal provides immediate access to some articles. Commentaries When astrocytes signal, kainate receptors respond Matthew Frerking PMCID: PMC365674 Bdelloid rotifers revisited C. William Birky, Jr. PMCID: PMC365675 Perspective Integrating the genotype and phenotype in hominid paleontology Leslea J. Hlusko PMCID: PMC365676 Physical Sciences Applied Mathematics Defining and identifying communities in networks Filippo Radicchi, Claudio Castellano, Federico Cecconi, Vittorio Loreto, and Domenico Parisi PMCID: PMC365677 Fluorescence correlation spectroscopy with high-order and dual-color correlation to probe nonequilibrium steady states Hong Qian and Elliot L. Elson PMCID: PMC365705 Chemistry Metallic single-walled silicon nanotubes Jaeil Bai, X. C. Zeng, Hideki Tanaka, and J. Y. Zeng PMCID: PMC365678 Stereochemistry in self-assembled encapsulation complexes: Constellational isomerism Masamichi Yamanaka, Alexander Shivanyuk, and Julius Rebek, Jr. PMCID: PMC365679 From the Cover:
The X3LYP extended density functional for accurate descriptions of nonbond interactions, spin states, and thermochemical properties Xin Xu and William A. Goddard, III PMCID: PMC374194 Targeted analysis and discovery of posttranslational modifications in proteins from methanogenic archaea by top-down MS Andrew J. Forbes, Steven M. Patrie, Gregory K. Taylor, Yong-Bin Kim, Lihua Jiang, and Neil L. Kelleher PMCID: PMC365680 The nonconserved wrapping of conserved protein folds reveals a trend toward increasing connectivity in proteomic networks Ariel Fernández, Ridgway Scott, and R. Stephen Berry PMCID: PMC365704 Mathematics The vortex patch problem for the surface quasi-geostrophic equation José Luis Rodrigo PMCID: PMC374195 Almost sharp fronts for the surface quasi-geostrophic equation Diego Córdoba, Charles Fefferman, and José Luis Rodrigo PMCID: PMC365681 Biological Sciences Anthropology Impetus for sowing and the beginning of agriculture: Ground collecting of wild cereals Mordechai E. Kislev, Ehud Weiss, and Anat Hartmann PMCID: PMC373256 Applied Biological Sciences Induction and transmission of Bacillus thuringiensis tolerance in the flour moth Ephestia kuehniella M. Mahbubur Rahman, Harry L. S. Roberts, Muhammad Sarjan, Sassan Asgari, and Otto Schmidt PMCID: PMC365683 Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux Jayong Chung, David J. Haile, and Marianne Wessling-Resnick PMCID: PMC365684 Biochemistry Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Chih-chin Huang, Miro Venturi, Shahzad Majeed, Michael J. Moore, Sanjay Phogat, Mei-Yun Zhang, Dimiter S. Dimitrov, Wayne A. Hendrickson, James Robinson, Joseph Sodroski, Richard Wyatt, Hyeryun Choe, Michael Farzan, and Peter D. Kwong PMCID: PMC365685 The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro Jan D. Kahmann, Diana A. Wecking, Vera Putter, Ky Lowenhaupt, Yang-Gyun Kim, Peter Schmieder, Hartmut Oschkinat, Alexander Rich, and Markus Schade PMCID: PMC365686 Crystal structure of the complex between thrombin and the central “E” region of fibrin Igor Pechik, Joel Madrazo, Michael W. Mosesson, Irene Hernandez, Gary L. Gilliland, and Leonid Medved PMCID: PMC365687 Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid Juan Reguera, Aura Carreira, Laura Riolobos, José María Almendral, and Mauricio G. Mateu PMCID: PMC365688 Transition state stabilization by general acid catalysis, water expulsion, and enzyme reorganization in Medicago savita chalcone isomerase Sun Hur, Zachary E. R. Newby, and Thomas C. Bruice PMCID: PMC365689 Predicted 3D structure for the human β2 adrenergic receptor and its binding site for agonists and antagonists Peter L. Freddolino, M. Yashar S. Kalani, Nagarajan Vaidehi, Wely B. Floriano, Spencer E. Hall, Rene J. Trabanino, Victor Wai Tak Kam, and William A. Goddard, III PMCID: PMC365690 ADP reduces the oxygen-binding affinity of a sensory histidine kinase, FixL: The possibility of an enhanced reciprocating kinase reaction Hiro Nakamura, Hideyuki Kumita, Kiyohiro Imai, Tetsutaro Iizuka, and Yoshitsugu Shiro PMCID: PMC365691 Recycling of a regulatory protein by degradation of the RNA to which it binds Gintaras Deikus, Paul Babitzke, and David H. Bechhofer PMCID: PMC365692 Nuclear localization and molecular partners of BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors Philip Ian Padilla, Gustavo Pacheco-Rodriguez, Joel Moss, and Martha Vaughan PMCID: PMC365693 Global analysis of Escherichia coli RNA degradosome function using DNA microarrays Jonathan A. Bernstein, Pei-Hsun Lin, Stanley N. Cohen, and Sue Lin-Chao PMCID: PMC365694 Single-molecule and transient kinetics investigation of the interaction of dihydrofolate reductase with NADPH and dihydrofolate Zhiquan Zhang, P. T. Ravi Rajagopalan, Tzvia Selzer, Stephen J. Benkovic, and Gordon G. Hammes PMCID: PMC371724 Two structural features of λ integrase that are critical for DNA cleavage by multimers but not by monomers Sang Yeol Lee, Hideki Aihara, Tom Ellenberger, and Arthur Landy PMCID: PMC365695 Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions Johannes D. Clausen, Bente Vilsen, David B. McIntosh, Anja P. Einholm, and Jens Peter Andersen PMCID: PMC365696 Identification of critical residues in GlnB for its activation of NifA activity in the photosynthetic bacterium Rhodospirillum rubrum Yaoping Zhang, Edward L. Pohlmann, and Gary P. Roberts PMCID: PMC365697 Portability and fidelity of RNA-repair systems Beate Schwer, Rana Sawaya, C. Kiong Ho, and Stewart Shuman PMCID: PMC365698 Differential utilization of upstream AUGs in the β-secretase mRNA suggests that a shunting mechanism regulates translation George W. Rogers, Jr., Gerald M. Edelman, and Vincent P. Mauro PMCID: PMC365699 Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled γ-phosphate-linked GTP analogs Jonas Korlach, Daniel W. Baird, Ahmed A. Heikal, Kyle R. Gee, Gregory R. Hoffman, and Watt W. Webb PMCID: PMC365700 CIS display: In vitro selection of peptides from libraries of protein–DNA complexes Richard Odegrip, David Coomber, Bill Eldridge, Rosemarie Hederer, Philip A. Kuhlman, Christopher Ullman, Kevin FitzGerald, and Duncan McGregor PMCID: PMC365701 Two discriminatory binding sites in the Escherichia coli replication origin are required for DNA strand opening by initiator DnaA-ATP Kevin C. McGarry, Valorie T. Ryan, Julia E. Grimwade, and Alan C. Leonard PMCID: PMC365702 Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture Natàlia Reixach, Songpon Deechongkit, Xin Jiang, Jeffery W. Kelly, and Joel N. Buxbaum PMCID: PMC365703 The nonconserved wrapping of conserved protein folds reveals a trend toward increasing connectivity in proteomic networks Ariel Fernández, Ridgway Scott, and R. Stephen Berry PMCID: PMC365704 Biophysics Fluorescence correlation spectroscopy with high-order and dual-color correlation to probe nonequilibrium steady states Hong Qian and Elliot L. Elson PMCID: PMC365705 Solvation in protein folding analysis: Combination of theoretical and experimental approaches A. M. Fernández-Escamilla, M. S. Cheung, M. C. Vega, M. Wilmanns, J. N. Onuchic, and L. Serrano PMCID: PMC365706 The archaeal feast/famine regulatory protein: Potential roles of its assembly forms for regulating transcription Hideaki Koike, Sanae A. Ishijima, Lester Clowney, and Masashi Suzuki PMCID: PMC365707 Imprint of evolution on protein structures Guido Tiana, Boris E. Shakhnovich, Nikolay V. Dokholyan, and Eugene I. Shakhnovich PMCID: PMC365708 Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli Che Ma and Geoffrey Chang PMCID: PMC365709 Determinants of liposome fusion mediated by synaptic SNARE proteins Christina G. Schuette, Kiyotaka Hatsuzawa, Martin Margittai, Alexander Stein, Dietmar Riedel, Petra Küster, Marcelle König, Claus Seidel, and Reinhard Jahn PMCID: PMC365710 Engineering biological structures of prescribed shape using self-assembling multicellular systems Karoly Jakab, Adrian Neagu, Vladimir Mironov, Roger R. Markwald, and Gabor Forgacs PMCID: PMC365711 Cell Biology A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway Erik Bush, Jens Fielitz, Lawrence Melvin, Michael Martinez-Arnold, Timothy A. McKinsey, Ryan Plichta, and Eric N. Olson PMCID: PMC365712 Molecular chaperones function as steroid receptor nuclear mobility factors Cem Elbi, Dawn A. Walker, Guillermo Romero, William P. Sullivan, David O. Toft, Gordon L. Hager, and Donald B. DeFranco PMCID: PMC365713 Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin Feng Cong and Harold Varmus PMCID: PMC365714 Whole-genome annotation by using evidence integration in functional-linkage networks Ulas Karaoz, T. M. Murali, Stan Letovsky, Yu Zheng, Chunming Ding, Charles R. Cantor, and Simon Kasif PMCID: PMC365715 Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia Vladimir Chubanov, Siegfried Waldegger, Michael Mederos y Schnitzler, Helga Vitzthum, Martin C. Sassen, Hannsjörg W. Seyberth, Martin Konrad, and Thomas Gudermann PMCID: PMC365716 Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling Wendy Prudhomme, George Q. Daley, Peter Zandstra, and Douglas A. Lauffenburger PMCID: PMC365717 Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring Wei Yang, Motomu Shimaoka, Azucena Salas, Junichi Takagi, and Timothy A. Springer PMCID: PMC365718 Fluorescence-activated cell sorting (FACS) of Drosophila hemocytes reveals important functional similarities to mammalian leukocytes Rabindra Tirouvanziam, Colin J. Davidson, Joseph S. Lipsick, and Leonard A. Herzenberg PMCID: PMC365719 From the Cover:
Transportin2 functions as importin and mediates nuclear import of HuR Stephan Güttinger, Petra Mühlhäusser, Roland Koller-Eichhorn, Julius Brennecke, and Ulrike Kutay PMCID: PMC365720 Developmental Biology Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development Catherine L. Prado, Aimee E. Pugh-Bernard, Lynda Elghazi, Beatriz Sosa-Pineda, and Lori Sussel PMCID: PMC365721 The MafA transcription factor appears to be responsible for tissue-specific expression of insulin Taka-aki Matsuoka, Isabella Artner, Eva Henderson, Anna Means, Maike Sander, and Roland Stein PMCID: PMC365722 Ecology Transgenic male mating advantage provides opportunity for Trojan gene effect in a fish Richard D. Howard, J. Andrew DeWoody, and William M. Muir PMCID: PMC365723 Evolution Imprint of evolution on protein structures Guido Tiana, Boris E. Shakhnovich, Nikolay V. Dokholyan, and Eugene I. Shakhnovich PMCID: PMC365708 Structural and functional divergence of insect CYP6B proteins: From specialist to generalist cytochrome P450 Xianchun Li, Jerome Baudry, May R. Berenbaum, and Mary A. Schuler PMCID: PMC365724 Surface hydrocarbons of queen eggs regulate worker reproduction in a social insect Annett Endler, Jürgen Liebig, Thomas Schmitt, Jane E. Parker, Graeme R. Jones, Peter Schreier, and Bert Hölldobler PMCID: PMC365725 Adaptive role of increased frequency of polypurine tracts in mRNA sequences of thermophilic prokaryotes Arnon Paz, David Mester, Ivan Baca, Eviatar Nevo, and Abraham Korol PMCID: PMC365726 Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles Monica Uddin, Derek E. Wildman, Guozhen Liu, Wenbo Xu, Robert M. Johnson, Patrick R. Hof, Gregory Kapatos, Lawrence I. Grossman, and Morris Goodman PMCID: PMC365727 Genetics Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene Zhipei Liu, Manfred Hergenhahn, Heinz H. Schmeiser, Gerald N. Wogan, Amanda Hong, and Monica Hollstein PMCID: PMC365728 Intrachromosomal excision of a hybrid Ds element induces large genomic deletions in Arabidopsis Damian R. Page, Claudia Köhler, José A. da Costa-Nunes, Célia Baroux, James M. Moore, and Ueli Grossniklaus PMCID: PMC365729 Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification Taisuke Hosaka, William H. Biggs, III, David Tieu, Antonia D. Boyer, Nissi M. Varki, Webster K. Cavenee, and Karen C. Arden PMCID: PMC365730 Revealing modularity and organization in the yeast molecular network by integrated analysis of highly heterogeneous genomewide data Amos Tanay, Roded Sharan, Martin Kupiec, and Ron Shamir PMCID: PMC365731 Identification of a target RNA motif for RNA-binding protein HuR Isabel López de Silanes, Ming Zhan, Ashish Lal, Xiaoling Yang, and Myriam Gorospe PMCID: PMC365732 Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect Gloria Esposito, Byjay S. Jaiswal, Fang Xie, Magda A. M. Krajnc-Franken, Tamara J. A. A. Robben, Ankie M. Strik, Cor Kuil, Ria L. A. Philipsen, Marcel van Duin, Marco Conti, and Jan A. Gossen PMCID: PMC365733 Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers George Adrian Calin, Cinzia Sevignani, Calin Dan Dumitru, Terry Hyslop, Evan Noch, Sai Yendamuri, Masayoshi Shimizu, Sashi Rattan, Florencia Bullrich, Massimo Negrini, and Carlo M. Croce PMCID: PMC365734 Immunology Intact type 1 immunity and immune-associated coagulative responses in mice lacking IFNγ-inducible fibrinogen-like protein 2 Wayne W. Hancock, Frank M. Szaba, Kiera N. Berggren, Michelle A. Parent, Isis K. Mullarky, John Pearl, Andrea M. Cooper, Kenneth H. Ely, David L. Woodland, In-Jeong Kim, Marcia A. Blackman, Lawrence L. Johnson, and Stephen T. Smiley PMCID: PMC365735 Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering Elena Sandalova, Cheng-Hong Wei, Maria G. Masucci, and Victor Levitsky PMCID: PMC365736 Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus Klara Tenner-Racz, Christiane Stahl Hennig, Klaus Überla, Heribert Stoiber, Ralf Ignatius, Jonathan Heeney, Ralph M. Steinman, and Paul Racz PMCID: PMC365737 Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation Binfeng Lu, Panayiotis Zagouras, James E. Fischer, Junfeng Lu, Baiyong Li, and Richard A. Flavell PMCID: PMC365738 TLR2 is expressed on activated T cells as a costimulatory receptor Mousa Komai-Koma, Louise Jones, Graham S. Ogg, Damo Xu, and Foo Y. Liew PMCID: PMC365739 Cellular protein is the source of cross-priming antigen in vivo Lianjun Shen and Kenneth L. Rock PMCID: PMC365740 Competition for self-peptide-MHC complexes and cytokines between naïve and memory CD8+ T cells expressing the same or different T cell receptors Qing Ge, Ailin Bai, Brendan Jones, Herman N. Eisen, and Jianzhu Chen PMCID: PMC365741 Medical Sciences Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis Thomas C. Beller, Daniel S. Friend, Akiko Maekawa, Bing K. Lam, K. Frank Austen, and Yoshihide Kanaoka PMCID: PMC365742 Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics Antonis Voutetakis, Marc R. Kok, Changyu Zheng, Ioannis Bossis, Jianghua Wang, Ana P. Cotrim, Natanya Marracino, Corinne M. Goldsmith, John A. Chiorini, Y. Peng Loh, Lynnette K. Nieman, and Bruce J. Baum PMCID: PMC365743 NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate Tapan K. Bera, Sudipto Das, Hiroshi Maeda, Richard Beers, Curt D. Wolfgang, Vasantha Kumar, Yoonsoo Hahn, Byungkook Lee, and Ira Pastan PMCID: PMC365744 Identification of a second bovine amyloidotic spongiform encephalopathy: Molecular similarities with sporadic Creutzfeldt-Jakob disease Cristina Casalone, Gianluigi Zanusso, Pierluigi Acutis, Sergio Ferrari, Lorenzo Capucci, Fabrizio Tagliavini, Salvatore Monaco, and Maria Caramelli PMCID: PMC365745 Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury Yang D. Teng, Howard Choi, Renna C. Onario, Shan Zhu, Federico C. Desilets, Shoumin Lan, Eric J. Woodard, Evan Y. Snyder, Marc E. Eichler, and Robert M. Friedlander PMCID: PMC365746 The SPANX gene family of cancer/testis-specific antigens: Rapid evolution and amplification in African great apes and hominids Natalay Kouprina, Michael Mullokandov, Igor B. Rogozin, N. Keith Collins, Greg Solomon, John Otstot, John I. Risinger, Eugene V. Koonin, J. Carl Barrett, and Vladimir Larionov PMCID: PMC365747 Glycosylation-independent targeting enhances enzyme delivery to lysosomes and decreases storage in mucopolysaccharidosis type VII mice Jonathan H. LeBowitz, Jeffrey H. Grubb, John A. Maga, Deborah H. Schmiel, Carole Vogler, and William S. Sly PMCID: PMC365748 Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients Tian-Li Wang, Luis A. Diaz, Jr., Katharine Romans, Alberto Bardelli, Saurabh Saha, Gennaro Galizia, Michael Choti, Ross Donehower, Giovanni Parmigiani, Ie-Ming Shih, Christine Iacobuzio-Donahue, Kenneth W. Kinzler, Bert Vogelstein, Christoph Lengauer, and Victor E. Velculescu PMCID: PMC420348 Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab Subhash C. Sinha, Lian-Sheng Li, Gregory P. Miller, Shantanu Dutta, Christoph Rader, and Richard A. Lerner PMCID: PMC365749 Role for neuronal insulin resistance in neurodegenerative diseases Markus Schubert, Dinesh Gautam, David Surjo, Kojihiko Ueki, Stephanie Baudler, Dominic Schubert, Tatsuya Kondo, Jens Alber, Norbert Galldiks, Eckehardt Küstermann, Saskia Arndt, Andreas H. Jacobs, Wilhelm Krone, C. Ronald Kahn, and Jens C. Brüning PMCID: PMC365750 Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene Kathleen M. I. Caron, Leighton R. James, Hyung-Suk Kim, Josh Knowles, Rick Uhlir, Lan Mao, John R. Hagaman, Wayne Cascio, Howard Rockman, and Oliver Smithies PMCID: PMC365751 The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity Jianchao Xu, Peili Wang, Yanyan Li, Guoyong Li, Leonard K. Kaczmarek, Yanling Wu, Pandelakis A. Koni, Richard A. Flavell, and Gary V. Desir PMCID: PMC365752 Activation of the Wnt signaling pathway in chronic lymphocytic leukemia Desheng Lu, Yandong Zhao, Rommel Tawatao, Howard B. Cottam, Malini Sen, Lorenzo M. Leoni, Thomas J. Kipps, Maripat Corr, and Dennis A. Carson PMCID: PMC365753 E1A and E1B proteins inhibit inflammation induced by adenovirus Jerome Schaack, Michael L. Bennett, Jeff D. Colbert, Andres Vazquez Torres, Gerald H. Clayton, David Ornelles, and John Moorhead PMCID: PMC365754 Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs M. Golam Mohi, Christina Boulton, Ting-Lei Gu, David W. Sternberg, Donna Neuberg, James D. Griffin, D. Gary Gilliland, and Benjamin G. Neel PMCID: PMC365755 A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts Anna Hansson, Nicole Hance, Eric Dufour, Anja Rantanen, Kjell Hultenby, David A. Clayton, Rolf Wibom, and Nils-Göran Larsson PMCID: PMC365756 Microbiology Outer-surface protein C of the Lyme disease spirochete: A protein induced in ticks for infection of mammals Dorothee Grimm, Kit Tilly, Rebecca Byram, Philip E. Stewart, Jonathan G. Krum, Dawn M. Bueschel, Tom G. Schwan, Paul F. Policastro, Abdallah F. Elias, and Patricia A. Rosa PMCID: PMC365757 Global analysis of nutrient control of gene expression in Saccharomyces cerevisiae during growth and starvation Jian Wu, Nianshu Zhang, Andrew Hayes, Kalliope Panoutsopoulou, and Stephen G. Oliver PMCID: PMC365758 Gene transfer in the evolution of parasite nucleotide biosynthesis Boris Striepen, Andrea J. P. Pruijssers, Jinling Huang, Catherine Li, Marc-Jan Gubbels, Nwakaso N. Umejiego, Lizbeth Hedstrom, and Jessica C. Kissinger PMCID: PMC365759 Trends between gene content and genome size in prokaryotic species with larger genomes Konstantinos T. Konstantinidis and James M. Tiedje PMCID: PMC365760 Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus Terrence M. Tumpey, Adolfo García-Sastre, Jeffery K. Taubenberger, Peter Palese, David E. Swayne, and Christopher F. Basler PMCID: PMC365761 Neuroscience From the Cover:
Astrocyte-mediated activation of neuronal kainate receptors Qing-song Liu, Qiwu Xu, Gregory Arcuino, Jian Kang, and Maiken Nedergaard PMCID: PMC365762 RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells Michele M. Maxwell, Piera Pasinelli, Aleksey G. Kazantsev, and Robert H. Brown, Jr. PMCID: PMC365763 Categorization in the monkey hippocampus: A possible mechanism for encoding information into memory Robert E. Hampson, Tim P. Pons, Terrence R. Stanford, and Sam A. Deadwyler PMCID: PMC365764 Clathrin-mediated endocytosis is required for compensatory regulation of GLR-1 glutamate receptors after activity blockade Maria E. Grunwald, Jerry E. Mellem, Nathalie Strutz, Andres V. Maricq, and Joshua M. Kaplan PMCID: PMC365765 From the Cover:
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: A major site of neurogenesis Wulf Haubensak, Alessio Attardo, Winfried Denk, and Wieland B. Huttner PMCID: PMC365766 Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex Masatoshi Suzuki, Lynda S. Wright, Padma Marwah, Henry A. Lardy, and Clive N. Svendsen PMCID: PMC365767 Plasma membrane localization signals in the light chain of botulinum neurotoxin Ester Fernández-Salas, Lance E. Steward, Helen Ho, Patton E. Garay, Sarah W. Sun, Marcella A. Gilmore, Joseph V. Ordas, Joanne Wang, Joseph Francis, and K. Roger Aoki PMCID: PMC365768 P2X7 receptors control 2-arachidonoylglycerol production by microglial cells Anke Witting, Lisa Walter, Jennifer Wacker, Thomas Möller, and Nephi Stella PMCID: PMC365769 Expression of functional receptors by the human γ-aminobutyric acid A γ2 subunit Ataúlfo Martínez-Torres and Ricardo Miledi PMCID: PMC365770 Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease Wyan-Ching Mimi Lee, Motojiro Yoshihara, and J. Troy Littleton PMCID: PMC365771 Correspondence of presaccadic activity in the monkey primary visual cortex with saccadic eye movements Hans Supèr, Chris van der Togt, Henk Spekreijse, and Victor A. F. Lamme PMCID: PMC365772 Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors Yan-You Huang, Eleanor Simpson, Christoph Kellendonk, and Eric R. Kandel PMCID: PMC365773 Pharmacology Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection Yuequan Shen, Natalia L. Zhukovskaya, Michael I. Zimmer, Sandriyana Soelaiman, Pamela Bergson, Chyung-Ru Wang, Craig S. Gibbs, and Wei-Jen Tang PMCID: PMC365774 K channel gating by an affinity-switching selectivity filter Antonius M. J. VanDongen PMCID: PMC365775 Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I Irmgard Tegeder, Domenico Del Turco, Achim Schmidtko, Matthias Sausbier, Robert Feil, Franz Hofmann, Thomas Deller, Peter Ruth, and Gerd Geisslinger PMCID: PMC365776 Physiology Serum leptin level is a regulator of bone mass F. Elefteriou, S. Takeda, K. Ebihara, J. Magre, N. Patano, C. Ae Kim, Y. Ogawa, X. Liu, S. M. Ware, W. J. Craigen, J. J. Robert, C. Vinson, K. Nakao, J. Capeau, and G. Karsenty PMCID: PMC365777 Alcohol inhibits luteinizing hormone-releasing hormone release by activating the endocannabinoid system Javier Fernández-Solari, Camila Scorticati, Claudia Mohn, Andrea De Laurentiis, Silvia Billi, Ana Franchi, Samuel M. McCann, and Valeria Rettori PMCID: PMC365778 Plant Biology Pseudomonas syringae pv. tomato cells encounter inhibitory levels of water stress during the hypersensitive response of Arabidopsis thaliana Catherine A. Wright and Gwyn A. Beattie PMCID: PMC365779 On the role of RNA silencing in the pathogenicity and evolution of viroids and viral satellites Ming-Bo Wang, Xue-Yu Bian, Li-Min Wu, Li-Xia Liu, Neil A. Smith, Daniel Isenegger, Rong-Mei Wu, Chikara Masuta, Vicki B. Vance, John M. Watson, Ali Rezaian, Elizabeth S. Dennis, and Peter M. Waterhouse PMCID: PMC365780 FRIGIDA-related genes are required for the winter-annual habit in Arabidopsis Scott D. Michaels, Isabel C. Bezerra, and Richard M. Amasino PMCID: PMC365781 Comparisons of pollen coat genes across Brassicaceae species reveal rapid evolution by repeat expansion and diversification Aretha Fiebig, Rebecca Kimport, and Daphne Preuss PMCID: PMC365782 CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis Xavier Daniel, Shoji Sugano, and Elaine M. Tobin PMCID: PMC365783 From the Cover:
Expression of an active tobacco mitogen-activated protein kinase kinase kinase enhances freezing tolerance in transgenic maize Huixia Shou, Patricia Bordallo, Jian-Bing Fan, Joanne M. Yeakley, Marina Bibikova, Jen Sheen, and Kan Wang PMCID: PMC365784 Blue light-induced transcription of plastid-encoded psbD gene is mediated by a nuclear-encoded transcription initiation factor, AtSig5 Yuichi Tsunoyama, Yoko Ishizaki, Kazuya Morikawa, Maki Kobori, Yoichi Nakahira, Go Takeba, Yoshinori Toyoshima, and Takashi Shiina PMCID: PMC365785 Psychology Two routes to emotional memory: Distinct neural processes for valence and arousal Elizabeth A. Kensinger and Suzanne Corkin PMCID: PMC365786 Social Sciences Anthropology Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles Monica Uddin, Derek E. Wildman, Guozhen Liu, Wenbo Xu, Robert M. Johnson, Patrick R. Hof, Gregory Kapatos, Lawrence I. Grossman, and Morris Goodman PMCID: PMC365727 Psychology Cardiovascular fitness, cortical plasticity, and aging Stanley J. Colcombe, Arthur F. Kramer, Kirk I. Erickson, Paige Scalf, Edward McAuley, Neal J. Cohen, Andrew Webb, Gerry J. Jerome, David X. Marquez, and Steriani Elavsky PMCID: PMC373255 Corrections Proc Natl Acad Sci U S A. 2004 March 2; 101(9): 3322. doi: 10.1073/pnas.0400055101.PMCID: PMC365788 Corrects: Tae-Woo Lee, et al. Organic light-emitting diodes formed by soft contact lamination. Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 429–433. Proc Natl Acad Sci U S A. 2004 March 2; 101(9): 3323. doi: 10.1073/pnas.0308741101.PMCID: PMC365789 Corrects: Peter Heil, et al. A unifying basis of auditory thresholds based on temporal summation. Proc Natl Acad Sci U S A. 2003 May 13; 100(10): 6151–6156. |
