| Background Review Document (BRD) | Overview | Other Validation Study Documents |
| Peer Review Panel | Presentations | Recommendations and Agency Responses |
| Test Method Evaluation Report |
Presentations
2008
M Paris, J Strickland, S Casati, R Tice, W Stokes. In Vitro Cytotoxicity Test Methods for Estimating Rat Acute Oral Toxicity: Prediction of GHS Acute Oral Hazard Categories. Society of Toxicology 47th Annual Meeting.
J Strickland, M Paris, D Allen, R Tice, W Stokes. An Alternative Use of In Vitro Cytotoxicity Test Data to Determine When Rat Acute Oral Toxicity Testing Should Start with the Limit Test. Society of Toxicology 47th Annual Meeting.
2007
J Strickland, M Paris, S Casati, E Harvey, R Lee, W Jones, A Rispin, R Tice, W Stokes. In Vitro cytotoxicity test methods for estimating starting doses for rat acute oral toxicity tests: impact on animal savings. Sixth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
M Paris, J Strickland, S Casati, R Tice, W Stokes. In Vitro cytotoxicity test methods for estimating rat acute oral toxicity: prediction of GHS acute oral toxicity categories. Sixth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
J Strickland, M Paris, S Casati, R Tice, W Stokes. The NICEATM/ECVAM validation study of in vitro cytotoxicity test methods for estimating rat acute oral toxicity. Sixth World Congress on Alternatives and Animal Use in the Life Sciences.
R Tice, J Strickland, M Paris, M Wind, W Stokes. Alternatives for acute oral systemic toxicity testing: NICEATM/ICCVAM current and planned activities. Sixth World Congress on Alternatives and Animal Use in the Life Sciences.
M Wind, A Rispin, R Tice, W Stokes. Reducing animal use for acute oral toxicity testing: ICCVAM recommendations for the use of in vitro cytotoxicity test methods. Sixth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
J Strickland, M Paris, S Casati, H Raabe, C Cao, R Clothier, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, E Harvey, R Lee, W Jones, M Wenk, M Vallant, J Charles, R Tice, W Stokes. Final results of the NICEATM/ECVAM validation study of in vitro cytotoxicity test methods for estimating rat acute oral toxicity. Society of Toxicology 46th Annual Meeting. View Poster.
M Wind, L Schechtman, A Rispin, R Tice, W Stokes. The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) recommendations for the use of in vitro cytotoxicity test methods to reduce animal use for acute oral toxicity testing. Society of Toxicology 46th Annual Meeting. View Poster.
2006
J Strickland, M Paris, S Casati, R Tice, W Stokes, R Lee, E Harvey, J Haseman, H Raabe, C Cao, R Clothier, G Mun, A Sizemore, GO Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, N Wenk, M Vallant. Reducing animal use in acute systemic toxicity testing by using in vitro cytotoxicity assays for estimating starting doses. Society of Toxicology 45th Annual Meeting. View Poster.
J Charles, J Strickland, M Paris, R Tice, W Stokes. The use of mouse fibroblast (3T3) and normal human epidermal keratinocyes (NHK) cytotoxicity assays for estimating acute oral toxicity of formulations and mixtures. Society of Toxicology 45th Annual Meeting. View Poster.
M Paris, J Strickland, S Casati, R Tice, W Stokes, H Raabe, C Cao, R Clothier,
J Harbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, E Harvey, R Lee, J Haseman, P Crockett, M Wenk, M Vallant.
Reproducibility analyses for in vitro neutral red
uptake methods from a validation study to evaluate in vitro cytotoxicity assays for estimating rodent acute systemic toxicity.
Society of Toxicology 45th Annual Meeting.
View Poster.
2005
M Paris, J Strickland, W Stokes, S Casati, R Tice, H Raabe, C Cao, R Clothier, J Harbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, J Haseman, P Crockett, M Wenk, M Vallant. Protocol optimization during a validation study to evaluate in vitro cytotoxicity assays for estimating rodent acute systemic toxicity. Fifth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
J Strickland, M Paris, H Raabe, J Haseman, S Casati, R Clothier, C Cao, P Crockett, R Tice, W Stokes. Data collection and analysis for an in vitro cytotoxicity validation study. Fifth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
W Stokes, M Paris, J Strickland, S Casati, R Tice, H Raabe, C Cao, R Clothier, JHarbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, J Haseman, P Crockett, E Harvey, R Lee, M Wenk, M Vallant. Results of the final phase of a validation study to evaluate in vitro cytotoxicity assays for estimating rodent acute systemic toxicity. Fifth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
M Paris, J Strickland, W Stokes, S Casati, R Tice, H Raabe, C Cao, R Clothier, J Haseman, P Crockett, M Wenk, M Vallant, G Mun, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne. Protocol optimization for the evaluation of In vitro cytotoxicity assays for estimating rodent and human acute systemic toxicity. Society of Toxicology 44th Annual Meeting. View Poster.
J Strickland, M Paris, W Stokes, S Casati, R Tice, H Raabe, C Cao, R Clothier, J Harbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, M Wenk, M Vallant. Evaluation of a solubility protocol for in vitro cytotoxicity testing. Society of Toxicology 44th Annual Meeting. View Poster.
2004
M Paris, J Strickland, W Stokes, S Casati, R Tice, H Raabe, C Cao, R Clothier, J Harbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, J Haseman, P Crockett, M Wenk, M Vallant, A Worth. Phase I and II results of a validation study to evaluate in vitro cytotoxicity assays for estimating rodent and human acute systemic toxicity. Society of Toxicology 43rd Annual Meeting. View Poster.
J Strickland, M Paris, H Raabe, JH Haseman, S Casati, R Clothier, C Cao, P Crockett, R Tice, W Stokes. Data collection and analysis systems for an in vitro cytotoxicity validation study. Society of Toxicology 43nd Annual Meeting. View Poster.
2003
S Casati, J Strickland, M Paris, W Stokes, R Tice, J Haseman, A Worth, H Raabe, C Cao, R Clothier, J Harbell, R Curren, M Wenk, M Vallant, G Mun, M Clear, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne. Preliminary (phase I) results of a validation study to evaluate the reliability and relevance of two in vitro cytotoxicity assays for predicting rodent and human acute systemic toxicity. EUROTOX 2003. View Poster.
M Paris, J Strickland, W Stokes, S Casati, H Raabe, C Cao, R Clothier, J Harbell, R Curren, J Haseman, R Tice, M Wenk, A Worth, M Vallant, G Mun, M Clear, G Moyer, J Madren-Whalley, C Krishna, M Owen and N Bourne. Design and phase Ia results of a validation study to evaluate in vitro cytotoxicity assays for predicting rodent and human acute systemic toxicity. 2003 Congress on In Vitro Biology. View Poster.
M Paris, J Strickland, R Tice, W Stokes. Establishment of rat LD50 reference values for chemicals tested in a validation study of in vitro cytotoxicity assays. Society of Toxicology 42nd Annual Meeting. View Poster.
J Strickland, W Stokes, S Casati, M Paris, A Worth, H Raabe, C Cao, R Clothier, J Harbell, R Curren, J Haseman, R Tice. Design of a Validation Study to Evaluate In vitro cytotoxicity assays for predicting rodent and human acute systemic toxicity. Society of Toxicology 42nd Annual Meeting. View Poster.
2002
M Paris, J Strickland, R Tice, W Stokes. Establishment of LD50 reference values for chemicals used in validation studies of in vitro cytotoxicity assays. Fourth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
W Stokes, M Balls, J Strickland, A Worth, M Paris, S Casati, R Tice. Validation study design to evaluate in vitro cytotoxicity assays for predicting rodent and human acute systemic toxicity. Fourth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
J Strickland, M Paris, R Tice, W Stokes, M Balls, A Worth, S Casati. Selection of reference chemicals for the validation of in vitro cytotoxicity assays for predicting in vivo acute systemic toxicity. Fourth World Congress on Alternatives and Animal Use in the Life Sciences. View Poster.
J Strickland, M Paris, R Tice, W Stokes. Selection of reference chemicals to validate in vitro cytotoxicity assays for estimating in vivo starting doses for acute oral toxicity. Society of Toxicology 41st Annual Meeting.
