| | This journal provides immediate access to some articles. Articles Contributions of hydrophobic domain interface interactions to the folding and stability of human γD-crystallin Shannon L. Flaugh, Melissa S. Kosinski-Collins, and Jonathan King PMCID: PMC2279286 Understanding the relationship between the primary structure of proteins and its propensity to be soluble on overexpression in Escherichia coli Susan Idicula-Thomas and Petety V. Balaji PMCID: PMC2279285 Hsp20, a novel α-crystallin, prevents Aβ fibril formation and toxicity Sungmun Lee, Kenneth Carson, Allison Rice-Ficht, and Theresa Good PMCID: PMC2279291 Protein folding: Defining a “standard” set of experimental conditions and a preliminary kinetic data set of two-state proteins Karen L. Maxwell, David Wildes, Arash Zarrine-Afsar, Miguel A. De Los Rios, Andrew G. Brown, Claire T. Friel, Linda Hedberg, Jia-Cherng Horng, Diane Bona, Erik J. Miller, Alexis Vallée-Bélisle, Ewan R.G. Main, Francesco Bemporad, Linlin Qiu, Kaare Teilum, Ngoc-Diep Vu, Aled M. Edwards, Ingo Ruczinski, Flemming M. Poulsen, Birthe B. Kragelund, Stephen W. Michnick, Fabrizio Chiti, Yawen Bai, Stephen J. Hagen, Luis Serrano, Mikael Oliveberg, Daniel P. Raleigh, Pernilla Wittung-Stafshede, Sheena E. Radford, Sophie E. Jackson, Tobin R. Sosnick, Susan Marqusee, Alan R. Davidson, and Kevin W. Plaxco PMCID: PMC2279278 Availability of short amino acid sequences in proteins Joji M. Otaki, Shunsuke Ienaka, Tomonori Gotoh, and Haruhiko Yamamoto PMCID: PMC2279279 Analysis of subsecond protein dynamics by amide hydrogen exchange and mass spectrometry using a quenched-flow setup Wolfgang Rist, Fernanda Rodriguez, Thomas J.D. Jørgensen, and Matthias P. Mayer PMCID: PMC2279298 Normal modes for predicting protein motions: A comprehensive database assessment and associated Web tool Vadim Alexandrov, Ursula Lehnert, Nathaniel Echols, Duncan Milburn, Donald Engelman, and Mark Gerstein PMCID: PMC2279292 Structural features of the focal adhesion kinase–paxillin complex give insight into the dynamics of focal adhesion assembly Craig M. Bertolucci, Cristina D. Guibao, and Jie Zheng PMCID: PMC2279287 Protein aggregation determinants from a simplified model: Cooperative folders resist aggregation Louis A. Clark PMCID: PMC2279276 All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin Lu Deng, Eugene S. Vysotski, Svetlana V. Markova, Zhi-Jie Liu, John Lee, John Rose, and Bi-Cheng Wang PMCID: PMC2279293 An efficient strategy for high-throughput expression screening of recombinant integral membrane proteins Said Eshaghi, Marie Hedrén, Marina Ignatushchenko Abdel Nasser, Tove Hammarberg, Anders Thornell, and Pär Nordlund PMCID: PMC2279288 Insights into the domains required for dimerization and assembly of human αB crystallin Joy G. Ghosh and John I. Clark PMCID: PMC2279284 β2-Microglobulin isoforms display an heterogeneous affinity for type I collagen Sofia Giorgetti, Antonio Rossi, Palma Mangione, Sara Raimondi, Sara Marini, Monica Stoppini, Alessandra Corazza, Paolo Viglino, Gennaro Esposito, Giuseppe Cetta, Giampaolo Merlini, and Vittorio Bellotti PMCID: PMC2279294 Test of the Binding Threshold Hypothesis for olfactory receptors: Explanation of the differential binding of ketones to the mouse and human orthologs of olfactory receptor 912-93 Patrick Hummel, Nagarajan Vaidehi, Wely B. Floriano, Spencer E. Hall, and William A. Goddard, III PMCID: PMC2279295 Identification of the ligand binding sites on the molecular surface of proteins Kengo Kinoshita and Haruki Nakamura PMCID: PMC2279290 Structure and mechanism of ADP-ribose-1″-monophosphatase (Appr-1″-pase), a ubiquitous cellular processing enzyme Desigan Kumaran, Subramaniam Eswaramoorthy, F. William Studier, and Subramanyam Swaminathan PMCID: PMC2279289 The crystal structure of rabbit phosphoglucose isomerase complexed with D-sorbitol-6-phosphate, an analog of the open chain form of D-glucose-6-phosphate Ji Hyun Lee and Constance J. Jeffery PMCID: PMC2279277 Microsecond timescale backbone conformational dynamics in ubiquitin studied with NMR R1ρ relaxation experiments Francesca Massi, Michael J. Grey, and Arthur G. Palmer, III PMCID: PMC2279275 Structural and mechanistic studies of chloride induced activation of human pancreatic α-amylase Robert Maurus, Anjuman Begum, Hsin-Hen Kuo, Andrew Racaza, Shin Numao, Carsten Andersen, Jeppe W. Tams, Jesper Vind, Christopher M. Overall, Stephen G. Withers, and Gary D. Brayer PMCID: PMC2279296 Solution structure of the PWWP domain of the hepatoma-derived growth factor family Nobukazu Nameki, Naoya Tochio, Seizo Koshiba, Makoto Inoue, Takashi Yabuki, Masaaki Aoki, Eiko Seki, Takayoshi Matsuda, Yukiko Fujikura, Miyuki Saito, Masaomi Ikari, Megumi Watanabe, Takaho Terada, Mikako Shirouzu, Mayumi Yoshida, Hiroshi Hirota, Akiko Tanaka, Yoshihide Hayashizaki, Peter Güntert, Takanori Kigawa, and Shigeyuki Yokoyama PMCID: PMC2279273 Impact of remote mutations on metallo-β-lactamase substrate specificity: Implications for the evolution of antibiotic resistance Peter Oelschlaeger, Stephen L. Mayo, and Juergen Pleiss PMCID: PMC2279297 Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis James Sandy, Simon Holton, Elizabeth Fullam, Edith Sim, and Martin Noble PMCID: PMC2279269 Dynamics of the gp130 cytokine complex: A model for assembly on the cellular membrane Andreas Schroers, Oliver Hecht, Karl-Josef Kallen, Michael Pachta, Stefan Rose-John, and Joachim Grötzinger PMCID: PMC2279283 Crystal structure of the pyridoxal-5′-phosphate-dependent serine dehydratase from human liver Lei Sun, Mark Bartlam, Yiwei Liu, Hai Pang, and Zihe Rao PMCID: PMC2279282 The orientations of cytochrome c in the highly dynamic complex with cytochrome b5 visualized by NMR and docking using HADDOCK Alexander N. Volkov, Davide Ferrari, Jonathan A.R. Worrall, Alexandre M.J.J. Bonvin, and Marcellus Ubbink PMCID: PMC2279274 Ligand-binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology-based kinetic analysis correlated with molecular dynamics simulation Liduo Yue, Fei Ye, Chunshan Gui, Haibin Luo, Jianhua Cai, Jianhua Shen, Kaixian Chen, Xu Shen, and Hualiang Jiang PMCID: PMC2279270 Protein Structure Report Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 Å resolution Mutsuko Kukimoto-Niino, Rie Shibata, Kazutaka Murayama, Hiroaki Hamana, Madoka Nishimoto, Yoshitaka Bessho, Takaho Terada, Mikako Shirouzu, Seiki Kuramitsu, and Shigeyuki Yokoyama PMCID: PMC2279281 For the Record Polymerization of the SAM domain of MAPKKK Ste11 from the budding yeast: Implications for efficient signaling through the MAPK cascades Surajit Bhattacharjya, Ping Xu, Mukundan Chakrapani, Linda Johnston, and Feng Ni PMCID: PMC2279271 Crystallization of bacteriorhodopsin from bicelle formulations at room temperature Salem Faham, Gabriella L. Boulting, Elizabeth A. Massey, Sarah Yohannan, Dawn Yang, and James U. Bowie PMCID: PMC2279272 Book Review Membrane protein protocols: Expression, purification and characterization, edited by Barry S. Selinsky. 2003.: Humana Press. $99.50. Lars-Oliver Essen PMCID: PMC2279280 |
