| | This journal provides immediate access to some articles. Research Articles Substrate-assisted catalysis: molecular basis and biological significance. W. Dall'Acqua and P. Carter Protein Sci. 2000 January; 9(1): 1–9. PMCID: PMC2144443 Folding and binding cascades: dynamic landscapes and population shifts. S. Kumar, B. Ma, C. J. Tsai, N. Sinha, and R. Nussinov Protein Sci. 2000 January; 9(1): 10–19. PMCID: PMC2144430 NMR analysis of cleaved Escherichia coli thioredoxin (1-73/74-108) and its P76A variant: cis/trans peptide isomerization. W. F. Yu, C. S. Tung, H. Wang, and M. L. Tasayco Protein Sci. 2000 January; 9(1): 20–28. PMCID: PMC2144445 The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors. N. Y. Chirgadze, D. J. Sall, S. L. Briggs, D. K. Clawson, M. Zhang, G. F. Smith, and R. W. Schevitz Protein Sci. 2000 January; 9(1): 29–36. PMCID: PMC2144429 Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase. J. E. Knapp, D. Carroll, J. E. Lawson, S. R. Ernst, L. J. Reed, and M. L. Hackert Protein Sci. 2000 January; 9(1): 37–48. PMCID: PMC2144448 Crystal structures of two mutants (K206Q, H207E) of the N-lobe of human transferrin with increased affinity for iron. A. H. Yang, R. T. MacGillivray, J. Chen, Y. Luo, Y. Wang, G. D. Brayer, A. B. Mason, R. C. Woodworth, and M. E. Murphy Protein Sci. 2000 January; 9(1): 49–52. PMCID: PMC2144434 The use of nucleotide analogs to evaluate the mechanism of the heterotropic response of Escherichia coli aspartate transcarbamoylase. J. B. Sakash, A. Tsen, and E. R. Kantrowitz Protein Sci. 2000 January; 9(1): 53–63. PMCID: PMC2144450 Conformational substates in different crystal forms of the photoactive yellow protein--correlation with theoretical and experimental flexibility. D. M. van Aalten, W. Crielaard, K. J. Hellingwerf, and L. Joshua-Tor Protein Sci. 2000 January; 9(1): 64–72. PMCID: PMC2144441 X-Ray crystal structure and molecular dynamics simulations of silver hake parvalbumin (Isoform B). R. C. Richardson, N. M. King, D. J. Harrington, H. Sun, W. E. Royer, and D. J. Nelson Protein Sci. 2000 January; 9(1): 73–82. PMCID: PMC2144442 Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB. K. S. Bateman, S. Anderson, W. Lu, M. A. Qasim, M. Laskowski, Jr, and M. N. James Protein Sci. 2000 January; 9(1): 83–94. PMCID: PMC2144452 Dynamics of the Hck-SH3 domain: comparison of experiment with multiple molecular dynamics simulations. D. A. Horita, W. Zhang, T. E. Smithgall, W. H. Gmeiner, and R. A. Byrd Protein Sci. 2000 January; 9(1): 95–103. PMCID: PMC2144440 Affinity cleavage at the divalent metal site of porcine NAD-specific isocitrate dehydrogenase. Y. C. Huang, S. Soundar, and R. F. Colman Protein Sci. 2000 January; 9(1): 104–111. PMCID: PMC2144432 Folding of beta-sandwich proteins: three-state transition of a fibronectin type III module. E. Cota and J. Clarke Protein Sci. 2000 January; 9(1): 112–120. PMCID: PMC2144439 Interaction with magnesium and ADP stabilizes both components of nitrogenase from Klebsiella pneumoniae against urea denaturation. L. Zou, M. C. Baguinon, X. Guo, S. Y. Guo, Y. Yu, and L. C. Davis Protein Sci. 2000 January; 9(1): 121–128. PMCID: PMC2144431 Antibody-detected folding: kinetics of surface epitope formation are distinct from other folding phases. C. S. Raman, R. Jemmerson, and B. T. Nall Protein Sci. 2000 January; 9(1): 129–137. PMCID: PMC2144437 Anti-HIV and anti-tumor protein MAP30, a 30 kDa single-strand type-I RIP, shares similar secondary structure and beta-sheet topology with the A chain of ricin, a type-II RIP. Y. X. Wang, J. Jacob, P. T. Wingfield, I. Palmer, S. J. Stahl, J. D. Kaufman, P. L. Huang, P. L. Huang, S. Lee-Huang, and D. A. Torchia Protein Sci. 2000 January; 9(1): 138–144. PMCID: PMC2144446 Apoflavodoxin (un)folding followed at the residue level by NMR. C. P. van Mierlo, J. M. van den Oever, and E. Steensma Protein Sci. 2000 January; 9(1): 145–157. PMCID: PMC2144449 A step toward the prediction of the fluorescence lifetimes of tryptophan residues in proteins based on structural and spectral data. A. Sillen, J. F. Díaz, and Y. Engelborghs Protein Sci. 2000 January; 9(1): 158–169. PMCID: PMC2144451 Phosphorylation and subcellular redistribution of high mobility group proteins 14 and 17, analyzed by mass spectrometry. D. F. Louie, K. K. Gloor, S. C. Galasinski, K. A. Resing, and N. G. Ahn Protein Sci. 2000 January; 9(1): 170–179. PMCID: PMC2144438 Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations. I. Tsigelny, I. N. Shindyalov, P. E. Bourne, T. C. Südhof, and P. Taylor Protein Sci. 2000 January; 9(1): 180–185. PMCID: PMC2144444 Amide proton hydrogen exchange rates for sperm whale myoglobin obtained from 15N-1H NMR spectra. S. Cavagnero, Y. Thériault, S. S. Narula, H. J. Dyson, and P. E. Wright Protein Sci. 2000 January; 9(1): 186–193. PMCID: PMC2144433 Kinetic evidence of an on-pathway intermediate in the folding of lysozyme. Y. Bai Protein Sci. 2000 January; 9(1): 194–196. PMCID: PMC2144436 Expectations from structural genomics. S. E. Brenner and M. Levitt Protein Sci. 2000 January; 9(1): 197–200. PMCID: PMC2144435 The pi-helix translates structure into function. T. M. Weaver Protein Sci. 2000 January; 9(1): 201–206. PMCID: PMC2144447 |