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Volume 9(1);  January 2000
Research Articles
Substrate-assisted catalysis: molecular basis and biological significance.
W. Dall'Acqua and P. Carter
Protein Sci. 2000 January; 9(1): 1–9.
PMCID: PMC2144443
Folding and binding cascades: dynamic landscapes and population shifts.
S. Kumar, B. Ma, C. J. Tsai, N. Sinha, and R. Nussinov
Protein Sci. 2000 January; 9(1): 10–19.
PMCID: PMC2144430
NMR analysis of cleaved Escherichia coli thioredoxin (1-73/74-108) and its P76A variant: cis/trans peptide isomerization.
W. F. Yu, C. S. Tung, H. Wang, and M. L. Tasayco
Protein Sci. 2000 January; 9(1): 20–28.
PMCID: PMC2144445
The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors.
N. Y. Chirgadze, D. J. Sall, S. L. Briggs, D. K. Clawson, M. Zhang, G. F. Smith, and R. W. Schevitz
Protein Sci. 2000 January; 9(1): 29–36.
PMCID: PMC2144429
Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase.
J. E. Knapp, D. Carroll, J. E. Lawson, S. R. Ernst, L. J. Reed, and M. L. Hackert
Protein Sci. 2000 January; 9(1): 37–48.
PMCID: PMC2144448
Crystal structures of two mutants (K206Q, H207E) of the N-lobe of human transferrin with increased affinity for iron.
A. H. Yang, R. T. MacGillivray, J. Chen, Y. Luo, Y. Wang, G. D. Brayer, A. B. Mason, R. C. Woodworth, and M. E. Murphy
Protein Sci. 2000 January; 9(1): 49–52.
PMCID: PMC2144434
The use of nucleotide analogs to evaluate the mechanism of the heterotropic response of Escherichia coli aspartate transcarbamoylase.
J. B. Sakash, A. Tsen, and E. R. Kantrowitz
Protein Sci. 2000 January; 9(1): 53–63.
PMCID: PMC2144450
Conformational substates in different crystal forms of the photoactive yellow protein--correlation with theoretical and experimental flexibility.
D. M. van Aalten, W. Crielaard, K. J. Hellingwerf, and L. Joshua-Tor
Protein Sci. 2000 January; 9(1): 64–72.
PMCID: PMC2144441
X-Ray crystal structure and molecular dynamics simulations of silver hake parvalbumin (Isoform B).
R. C. Richardson, N. M. King, D. J. Harrington, H. Sun, W. E. Royer, and D. J. Nelson
Protein Sci. 2000 January; 9(1): 73–82.
PMCID: PMC2144442
Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB.
K. S. Bateman, S. Anderson, W. Lu, M. A. Qasim, M. Laskowski, Jr, and M. N. James
Protein Sci. 2000 January; 9(1): 83–94.
PMCID: PMC2144452
Dynamics of the Hck-SH3 domain: comparison of experiment with multiple molecular dynamics simulations.
D. A. Horita, W. Zhang, T. E. Smithgall, W. H. Gmeiner, and R. A. Byrd
Protein Sci. 2000 January; 9(1): 95–103.
PMCID: PMC2144440
Affinity cleavage at the divalent metal site of porcine NAD-specific isocitrate dehydrogenase.
Y. C. Huang, S. Soundar, and R. F. Colman
Protein Sci. 2000 January; 9(1): 104–111.
PMCID: PMC2144432
Folding of beta-sandwich proteins: three-state transition of a fibronectin type III module.
E. Cota and J. Clarke
Protein Sci. 2000 January; 9(1): 112–120.
PMCID: PMC2144439
Interaction with magnesium and ADP stabilizes both components of nitrogenase from Klebsiella pneumoniae against urea denaturation.
L. Zou, M. C. Baguinon, X. Guo, S. Y. Guo, Y. Yu, and L. C. Davis
Protein Sci. 2000 January; 9(1): 121–128.
PMCID: PMC2144431
Antibody-detected folding: kinetics of surface epitope formation are distinct from other folding phases.
C. S. Raman, R. Jemmerson, and B. T. Nall
Protein Sci. 2000 January; 9(1): 129–137.
PMCID: PMC2144437
Anti-HIV and anti-tumor protein MAP30, a 30 kDa single-strand type-I RIP, shares similar secondary structure and beta-sheet topology with the A chain of ricin, a type-II RIP.
Y. X. Wang, J. Jacob, P. T. Wingfield, I. Palmer, S. J. Stahl, J. D. Kaufman, P. L. Huang, P. L. Huang, S. Lee-Huang, and D. A. Torchia
Protein Sci. 2000 January; 9(1): 138–144.
PMCID: PMC2144446
Apoflavodoxin (un)folding followed at the residue level by NMR.
C. P. van Mierlo, J. M. van den Oever, and E. Steensma
Protein Sci. 2000 January; 9(1): 145–157.
PMCID: PMC2144449
A step toward the prediction of the fluorescence lifetimes of tryptophan residues in proteins based on structural and spectral data.
A. Sillen, J. F. Díaz, and Y. Engelborghs
Protein Sci. 2000 January; 9(1): 158–169.
PMCID: PMC2144451
Phosphorylation and subcellular redistribution of high mobility group proteins 14 and 17, analyzed by mass spectrometry.
D. F. Louie, K. K. Gloor, S. C. Galasinski, K. A. Resing, and N. G. Ahn
Protein Sci. 2000 January; 9(1): 170–179.
PMCID: PMC2144438
Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations.
I. Tsigelny, I. N. Shindyalov, P. E. Bourne, T. C. Südhof, and P. Taylor
Protein Sci. 2000 January; 9(1): 180–185.
PMCID: PMC2144444
Amide proton hydrogen exchange rates for sperm whale myoglobin obtained from 15N-1H NMR spectra.
S. Cavagnero, Y. Thériault, S. S. Narula, H. J. Dyson, and P. E. Wright
Protein Sci. 2000 January; 9(1): 186–193.
PMCID: PMC2144433
Kinetic evidence of an on-pathway intermediate in the folding of lysozyme.
Y. Bai
Protein Sci. 2000 January; 9(1): 194–196.
PMCID: PMC2144436
Expectations from structural genomics.
S. E. Brenner and M. Levitt
Protein Sci. 2000 January; 9(1): 197–200.
PMCID: PMC2144435
The pi-helix translates structure into function.
T. M. Weaver
Protein Sci. 2000 January; 9(1): 201–206.
PMCID: PMC2144447
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