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Agent Name Methyl isothiocyanate
CAS Number 556-61-6
Formula C2-H3-N-S
Major Category Toxic Gases & Vapors
Synonyms Isothiocyanate de methyle [French]; Isothiocyanate de methyle [ISO-French]; Isothiocyanatomethane; Isothiocyanic acid, methyl ester; Isotiocianato de metilo [Spanish]; Isotiocianato di metile [Italian]; MIT; MeNCS; Methane, isothiocyanato-; Methyl isothiocyanate; Methyl mustard; Methyl mustard oil; Methyl-isothiocyanat [German]; Methylisothiocyanaat [Dutch]; Methylisothiocyanaat [Netherlands]; Methylisothiocyanat [Denmark]; Methylisothiokyanat [Czech]; Methylsenfoel [German]; Metile isotiocianato [Italian]; Mitc; Morton EP-161E; Trapex; Trapex-40; Trapexide; Vorlex (Nor-Am); Vorlex 201 (Nor-Am); Vortex; WN 12; UN2477; [ChemIDplus]
Category Other Toxic Gases & Vapors
Description Colorless crystals that sublime at room temperature; [HSDB]
Sources/Uses Used as an insecticide and soil fumigant; Possibly used as a chemical weapon; [HSDB] Released from a pesticide factory in Bhopal India in 1984, killing about 2.500 people and leaving many survivors with chronic lung disease; [Rom, p. 503-4]
Comments A strong irritant, vesicant, and lacrimator; Inhalation of high concentrations can cause bronchoconstriction, lung injury, seizures, and coma; [HSDB] May cause second or third degree burns after brief skin contact. [CHRIS]
Exposure Assessment
Skin Designation (ACGIH) Not evaluated
TIH Yes
Vapor Pressure 3.54 mm Hg
Lethal Concentration LC50 (rats) = 1,900 mg/m3/1H
Explanatory Notes Flash point = 20 deg F; [CAMEO]
Flammability (NFPA) 2: high ambient temperature required
Adverse Effects
Toxic Pneumonitis Yes
Dermatotoxin Skin Burns
Lacrimator Yes
Neurotoxin Other CNS Neurotoxin
Links to Other NLM Databases
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009