| Agent Name |
Triphenyl phosphate |
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| CAS Number |
115-86-6 |
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| Formula |
C18-H15-O4-P |
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| Major Category |
Other Classes |
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| Synonyms |
Celluflex TPP; Disflamoll TP; Phenyl phosphate ((PhO)3PO); Phosflex TPP; Phosphoric acid, triphenyl ester; TP (VAN); TPP; Trifenylfosfat [Czech]; Triphenoxyphosphine oxide; Triphenyl phosphate; Triphenylphosphate; [ChemIDplus] |
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| Category |
Phosphorus Compounds |
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| Description |
Colorless, crystalline powder with a phenol-like odor; [NIOSH] |
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| Sources/Uses |
Used as a plasticizer, fire-retardant, and substitute for camphor in celluloid; also used in lubricating oils and hydraulic fluids; [ACGIH] |
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| Comments |
Cholinesterase inhibition, but no cumulative toxicity, was observed in animal studies. A study of 33 workers (employed for an average of 7.4 years) in a plant manufacturing TPP found no adverse health effects. A slight reduction in erythrocyte cholinesterase activity was found in six workers. Occupational allergic contact dermatitis has been documented. [ACGIH] In high-dose animal studies, adverse effects include delayed paralysis similar to that seen with tri-o-cresyl phosphate. [HSDB] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
3 mg/m3 |
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| PEL (OSHA) |
3 mg/m3 |
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| IDLH (NIOSH) |
1000 mg/m3 |
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| Excerpts from Documentation for IDLHs |
Human data: Workers exposed to an average air concentration of 3.5 mg/m3 for as long as ten years showed no evidence of adverse clinical effects [Sutton et al. 1960]. . . . Basis for revised IDLH: The revised IDLH for triphenyl phosphate is 1,000 mg/m3 based on acute oral toxicity data in animals [Antonyuk 1974]. |
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| Vapor Pressure |
6.28 x 10 -06 mm Hg |
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| Explanatory Notes |
Flash point = 220 deg C; |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TRIPHENYL PHOSPHATE
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