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Agent Name 1,2,4-Trichlorobenzene
CAS Number 120-82-1
Formula C6-H3-Cl3
Major Category Solvents
Synonyms 1,2,4-Trichlorobenzene; 1,2,4-Trichlorobenzol; 1,3,4-Trichlorobenzene; Hostetex L-pec; Trojchlorobenzen [Polish]; unsym-Trichlorobenzene; [ChemIDplus] UN2321
Category Chlorinated Aromatic
Description Colorless liquid or crystalline solid (below 63 degrees F) with an aromatic odor; [NIOSH]
Sources/Uses Used as a dielectric and heat transfer fluid and as an intermediate for other organic chemicals; [ACGIH] Used as a degreaser, wood preservative, and dye solvent; [HSDB]
Comments Animal studies show 1,2,4-trichlorobenzene to be toxic to the liver, kidneys, and brain (central nervous system depressant). [ACGIH] A skin, eye, and respiratory tract irritant; May cause liver injury; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
Ceiling (ACGIH) 5 ppm
Vapor Pressure 0.46 mm Hg
Odor Threshold Low 2.96 ppm
Explanatory Notes Odor threshold from AIHA; Flash point = 105 deg C;
Flammability (NFPA) 1: must be preheated
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Hepatotoxin Hepatotoxin, Secondary
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: 1,2,4-TRICHLOROBENZENE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009