| Agent Name |
MBOCA |
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| Alternative Name |
4,4'-Methylene bis (2-chloroaniline) |
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| CAS Number |
101-14-4 |
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| Formula |
C13-H12-Cl2-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
3,3'-Dichlor-4,4'-diaminodiphenylmethan [German]; 3,3'-Dichloro-4,4'-diaminodifenilmetano [Italian]; 3,3'-Dichloro-4,4'-diaminodiphenylmethane; 3,3'-Dicloro-4,4'-diaminodifenilmetano [Italian]; 4,4'-Diamino-3,3'-dichlorodiphenylmethane; 4,4'-Methylene(bis)-chloroaniline; 4,4'-Methylenebis(2-chloroaniline); 4,4'-Methylenebis(o-chloroaniline); 4,4'-Methylenebis-2-chlorobenzenamine; 4,4-Metilene-bis-o-cloroanilina [Italian]; Aniline, 4,4'-methylenebis(2-chloro-; Benzenamine, 4,4'-methylenebis(2-chloro-; Bis amine; Bis(3-chloro-4-aminophenyl)methane; Bis(4-amino-3-chlorophenyl)methane; Bis-amine A; Bisamine; Bisamine S; CL-Mda; Cuamine M; Cuamine MT; Curalin M; Curene 442; Cyanaset; Dacpm; Di(-4-amino-3-chlorophenyl)methane; Di-(4-amino-3-clorofenil)metano [Italian]; Diamet Kh;LD 813; MOCA; MOCA (curing agent); Mboca; Methylene 4,4'-bis(o-chloroaniline); Methylene-bis-orthochloroaniline; Methylenebis(3-chloro-4-aminobenzene); Methylenebis(chloroaniline); Millionate M; Quodorole; p,p'-Methylenebis(alpha-chloroaniline); p,p'-Methylenebis(o-chloroaniline); p,p'-Methylenebis(ortho-chloroaniline); [ChemIDplus] |
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| Category |
Amines, Aromatic |
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| Description |
Tan-colored pellets or flakes with a faint, amine-like odor; [NIOSH] |
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| Sources/Uses |
Used as a curing agent for polyurethanes and epoxy resins; [ACGIH] |
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| Comments |
Causes bladder cancer and methemoglobinemia in animal toxicology studies; Listed in the table "Examples of Industrial Chemicals for Which Methemoglobin Formation is NOT the Principal Cause of Toxicity"; [ACGIH] Signs of poisoning include hematuria and methemoglobinemia; [Merck Index # 6059] |
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| Exposure Assessment |
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| BEI |
Total MBOCA in urine = screen at end of shift; |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
0.01 ppm |
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| Vapor Pressure |
2.86 x 10 -07 mm Hg |
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| Half Life |
Urine: 23 hours to several days; [TDR, p. 856] |
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| Reference Link |
ATSDR - ToxFAQs - 4,4'-Methylenebis(2-chloroaniline) (MBOCA) |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| IARC Carcinogen |
Probable Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 4,4'-METHYLENEBIS(2-CHLOROANILINE)
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