| Agent Name |
Isobutyl alcohol |
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| CAS Number |
78-83-1 |
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| Formula |
C4-H10-O |
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| Major Category |
Solvents |
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| Synonyms |
1-Hydroxymethylpropane; 1-Propanol, 2-methyl-; 2-Methyl propanol; 2-Methyl-1-propanol; 2-Methylpropyl alcohol; Alcool isobutylique [French]; Fermentation butyl alcohol; Isobutanol; Isobutyl alcohol; Isobutyl alcohol (natural); Isobutylalkohol [Czech]; Isopropylcarbinol; [ChemIDplus] UN1212 |
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| Category |
Alcohols and Polyols |
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| Description |
Colorless, oily liquid with a sweet, musty odor; [NIOSH] |
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| Sources/Uses |
Used as solvent in lacquers, paint removers, and liquid chromatography; used in organic synthesis; [ACGIH] |
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| Comments |
In mice, 6400 ppm produces narcosis, but not death. [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
50 ppm |
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| PEL (OSHA) |
100 ppm |
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| MAK |
100 ppm |
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| IDLH (NIOSH) |
1600 ppm |
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| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by Patty [1963] that 2 of 6 rats died when exposed for 4 hours to 8,000 ppm [Smyth et al. 1954]. . . . Human data: None relevant for use in determining the revised IDLH; |
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| Vapor Pressure |
10.5 mm Hg |
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| Odor Threshold Low |
0.66 ppm |
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| Odor Threshold High |
40 ppm |
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| RD50 |
1818 ppm |
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| Lethal Concentration |
LCLo (rats) = 8,000 ppm/4H |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 3.6 ppm); Flash point = 82 deg F; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ISOBUTYL ALCOHOL
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