| Agent Name |
Hexylene glycol |
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| CAS Number |
107-41-5 |
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| Formula |
C6-H14-O2 |
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| Major Category |
Solvents |
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| Synonyms |
(+-)-2-Methyl-2,4-pentanediol; 1,1,3-Trimethyltrimethylenediol; 2,4-Dihydroxy-2-methylpentane; 2,4-Pentanediol, 2-methyl-; 2-Methyl pentane-2,4-diol; 2-Methyl-2,4-pentanediol; 4-Methyl-2,4-pentanediol; Diolane; Hexylene glycol; Isol; Pinakon; alpha,alpha,alpha'-Trimethyltrimethylene glycol; [ChemIDplus] |
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| Category |
Alcohols and Polyols |
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| Description |
Colorless liquid with a mild, sweetish odor; [NIOSH] |
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| Sources/Uses |
Used in the chemical, petroleum refining, and cosmetic industries; used as an additive to hydraulic fluids, inks, and cement; [ACGIH] |
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| Comments |
At 1000 ppm, subjects complain of eye, throat, and respiratory irritation. Oral dosing causes central nervous system depression in experimental animals. [ACGIH] Allergic contact dermattis may occur; [Reference #1] A skin, eye, and respiratory tract irritant; [ICSC] |
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| Reference Link |
Skin reactions to hexylene glycol |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| Ceiling (ACGIH) |
25 ppm |
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| MAK |
10 ppm |
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| Vapor Pressure |
0.05 mm Hg |
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| Odor Threshold Low |
50 ppm |
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| Odor Threshold High |
100 ppm |
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| Lethal Concentration |
LC50 (rats) > 310 mg/m3/1h |
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| Explanatory Notes |
Flash point = 96 deg C;Odor threshold from CHEMINFO; |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-METHYL-2,4-PENTANEDIOL
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