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Agent Name sec-Hexyl acetate
CAS Number 108-84-9
Formula C8-H16-O2
Major Category Solvents
Synonyms 1,3-Dimethylbutyl acetate; 1,3-Dimethylbutyl ethanoate; 1,3-Dimethylbutylester kyseliny octove [Czech]; 2-Pentanol, 4-methyl-, acetate; 4-Methyl-2-amyl acetate; 4-Methyl-2-pentanol, acetate; 4-Methyl-2-pentyl acetate; Acetic acid, 1,3-dimethylbutyl ester; Methyl amyl acetate; Methylamyl acetate; Methylisoamyl acetate; Methylisobutylcarbinol acetate; Methylisobutylcarbinyl acetate; sek.Isohexylester kyseliny octove [Czech]; [ChemIDplus] UN1233
Category Esters
Description Colorless liquid with a mild, pleasant, fruity odor; [NIOSH]
Sources/Uses Used as a lacquer solvent and fragrance; [ACGIH]
Comments Esters may induce narcosis in animals, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 50 ppm
PEL (OSHA) 50 ppm
IDLH (NIOSH) 500 ppm
Excerpts from Documentation for IDLHs Volunteers noted an unpleasant odor and irritation of the eyes and upper respiratory tract at 100 ppm [Silverman et al. 1946].
Vapor Pressure 4 mm Hg
Odor Threshold Low 0.39 ppm
Lethal Concentration LCLo (rats) = 2,000 ppm/4H
Explanatory Notes Odor threshold from AIHA; Flash point = 45 deg C;
Flammability (NFPA) 2: high ambient temperature required
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: 4-METHYL-2-PENTYL ACETATE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009