| Agent Name |
Hexafluoroacetone |
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| CAS Number |
684-16-2 |
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| Formula |
C3-F6-O |
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| Major Category |
Toxic Gases & Vapors |
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| Synonyms |
1,1,1,3,3,3-Hexafluoro-2-propanone; 2-Propanone, 1,1,1,3,3,3-hexafluoro-; 6FK; Acetone, hexafluoro-; GC 7887; Hexafluoroacetone; Perfluoro-2-propanone; Perfluoroacetone; [ChemIDplus] UN2420 |
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| Category |
Corrosive Gases |
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| Description |
Colorless gas with a musty odor. [Note: Shipped as a liquefied compressed gas.]; [NIOSH] |
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| Sources/Uses |
Used in the synthesis of organic chemicals and polymers; [ACGIH] |
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| Comments |
In 4-hour inhalation studies of rats, 300 ppm is lethal, 200 ppm causes liver and kidney injury, and 100 ppm causes testicular damage; evidence of bone marrow injury is also seen; [ACGIH] Possible frostbite from contact with liquid; [NIOSH] Inhalation of vapor can cause pulmonary edema; A skin, eye, and respiratory tract irritant; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TIH |
Yes |
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| TLV (ACGIH) |
0.1 ppm |
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| Lethal Concentration |
LC50 (rats) = 275 ppm/3h |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Nephrotoxin |
Yes |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,1,1,3,3,3-HEXAFLUORO-2-PROPANONE
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