Agent Name |
Ethyl silicate |
Alternative Name |
Tetraethylorthosilicate |
CAS Number |
78-10-4 |
Formula |
C8-H20-O4-Si |
Major Category |
Metals |
Synonyms |
Dynasil A; ES 100; ES 28; ES 28 (ester); Ethyl orthosilicate; Ethyl silicate, ((EtO)4Si); Etylu krzemian [Polish]; Orthosilicic acid, tetraethyl ester; Silane, tetraethoxy-; Silicate d'ethyle [French]; Silicate tetraethylique [French]; Silicic acid, tetraethyl ester; Silicon ethoxide; Silicon tetraethoxide; Silikan L; TEOS; TEOS (VAN); Tetraethoxysilane; Tetraethoxysilicon; Tetraethyl orthosilicate; Tetraethyl silicate; Tetraethyl-O-silicate; Tetraethylsilikat [Czech]; [ChemIDplus] UN1292 |
Category |
Metalloids and Compounds |
Description |
Colorless liquid with a sharp, alcohol-like odor; [NIOSH] |
Sources/Uses |
Used in mortar and surface coatings to improve resistance to weather and chemical corrosion; [ACGIH] Used in the semiconductor/electronics industry; [CSH, p. 375] Used in castings for alloys with high melting points, copper alloys, and dental prosthetic devices; Also used as a source of silicon dioxide by vapor deposition and to produce refractory bricks and heat-resistant paints; [HSDB] |
Comments |
Rats that survived concentrations of 400 ppm for 7 hours/day for 30 days show liver, kidney, and lung damage. [ACGIH] A skin and respiratory tract irritant; Liquid defats the skin and vapor may depress consciousness; [ICSC] In high-dose animal experiments, it acts as a general anesthetic; [ChemIDplus] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
10 ppm |
PEL (OSHA) |
100 ppm |
MAK |
10 ppm |
IDLH (NIOSH) |
700 ppm |
Excerpts from Documentation for IDLHs |
Human data: Exposure to a concentration of 1,200 ppm caused lacrimation and 250 ppm caused irritation of the eyes and nose [Smyth and Seaton 1940]. It has been stated that 700 ppm is probably intolerable for more than 30 minutes [Smyth and Seaton 1940]. |
Vapor Pressure |
1.88 mm Hg |
Odor Threshold Low |
3.6 ppm |
Lethal Concentration |
LCLo (rats) = 1,000 ppm/4H |
Explanatory Notes |
Detection odor threshold from AIHA (mean = 3.6 ppm); Flash point = 99 deg F; |
Flammability (NFPA) |
3: may ignite at ambient temperature |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Hepatotoxin |
Hepatotoxin, Secondary |
Nephrotoxin |
Yes |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ETHYL SILICATE
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