| Agent Name |
Polybrominated biphenyls |
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| CAS Number |
59536-65-1 |
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| Major Category |
Other Classes |
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| Synonyms |
Firemaster BP-6; Biphenyl, hexabromo- (technical grade); Hexabromobiphenyl (technical grade); PBB; Polybrominated biphenyls; [ChemIDplus] |
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| Category |
Halogenated Cyclics |
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| Sources/Uses |
Used as flame retardants; [Sullivan, p. 766] |
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| Comments |
In animal studies, the effects are similar to those of PCBs. No human diseases have been linked to occupational exposure to polybrominated biphenyls. [Sullivan, p. 766] Listed in a table of "Chloracne-Producing Chemicals"; [Rosenstock, p. 714] There is evidence that PBBs can cause fetal loss and testicular damage in experimental animals. [ATSDR Case Studies #29] "The accepted view is that exposure to PBBs or PCBs leads to hepatic injury only when they are sufficiently contaminated with PCDFs." (PCDFs = polychlorinated dibenzofurans.) [Zimmerman, p. 395] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Bioaccumulates |
Yes |
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| Reference Link |
ATSDR - ToxFAQs - Polybrominated Biphenyls (PBBs) |
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| Adverse Effects |
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| Dermatotoxin |
Chloracne |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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