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Disease/Syndrome Southern tick-associated rash illness
Category Infection, Occupational
Acute/Chronic Acute-Moderate
Synonyms STARI
Comments This disease has not yet been completely defined. It resembles Lyme disease with the typical erythema migrans type of rash. However, Southern tick-associated rash illness (STARI) follows the bite of the lone star tick (Amblyomma americanum) while Lyme disease follows the bite of the black-legged tick (Ixodes scapularis or Ixodes pacificis). The spirochete, Borrelia burgdorferi, causes Lyme disease. Tests for Borrelia burgdorferi are negative in patients with STARI. A spirochete has been identified by electron microscopy in patients with STARI, but this organism has not yet been cultured. In case reports of patients with STARI, rash and flu-like symptoms resolved quickly after initiation of doxycycline therapy. [See hyperlink for references] Most cases appear to be caused by viral infections (not by Borrelia species) following the bite of the Lone star tick. [IDSA Guidelines. Clinical Infectious Diseases. 2006;43:1089-1134]
Latency/Incubation 6 days
Diagnostic Testing available through CDC;
Effective Antimicrobics Yes
Scope Southeastern USA
Reference Link CDC - STARI
Related Information in Haz-Map
Symptoms/Findings Symptoms/Findings associated with this disease:
Job Tasks High risk job tasks associated with this disease:





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Last updated: January, 2009