| Agent Name |
Hexachlorobutadiene |
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| CAS Number |
87-68-3 |
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| Formula |
C4-Cl6 |
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| Major Category |
Other Classes |
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| Synonyms |
1,1,2,3,4,4-Hexachloro-1,3-butadiene; 1,3-Butadiene, 1,1,2,3,4,4-hexachloro-; 1,3-Butadiene, hexachloro-; 1,3-Hexachlorobutadiene; C 46; C-46; Dolen-pur; GP-40-66:120; HCBD; Hexachlor-1,3-butadien [Czech]; Hexachlorobutadiene; Perchlorobutadiene; [ChemIDplus] UN2279 |
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| Category |
Halogenated Aliphatics |
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| Description |
Clear, colorless liquid with a mild, turpentine-like odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent, heat transfer liquid in transformers, and hydraulic fluid; produced as a byproduct of hydrocarbon chlorination processes; [ACGIH] Used as a fumigant in parts of Europe against Phylloxera on grapes; [HSDB] |
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| Comments |
Kidney injury reported in chronic feeding and inhalation studies of experimental animals; [ACGIH] Liquid is corrosive. Vapor causes skin, eye, and respiratory tract irritation. May cause kidney injury; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
0.02 ppm |
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| Vapor Pressure |
0.2 mm Hg |
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| Odor Threshold Low |
1.1 ppm |
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| Lethal Concentration |
LC50 (mouse) = 370 mg/m3 |
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| Explanatory Notes |
Flash point = 90 deg C; Odor threshold from CHEMINFO; |
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| Reference Link |
ATSDR - ToxFAQs - Hexachlorobutadiene |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Dermatotoxin |
Skin Burns |
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| Nephrotoxin |
Yes |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: HEXACHLORO-1,3-BUTADIENE
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