| Agent Name |
Dibutyl phthalate |
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| Alternative Name |
Di-n-butyl phthalate |
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| CAS Number |
84-74-2 |
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| Formula |
C16-H22-O4 |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
1,2-Benzenedicarboxylic acid, dibutyl ester; AI-3-00283; Benzene-o-dicarboxylic acid di-n-butyl ester; Butyl phthalate; Celluflex DPB; DBP; DBP (ester); Di-n-butyl phthalate; Di-n-butylester kyseliny ftalove [Czech]; Dibutyl 1,2-benzenedicarboxylate; Dibutyl phthalate; Dibutyl-o-phthalate; Elaol; Ergoplast FDB; Ersoplast FDA; Genoplast B; Hatcol DBP; Hexaplas M/B; Kodaflex DBP; N-Butylphthalate; PX 104; Palatinol C; Phthalate, di-n-butyl; Phthalate, dibutyl-; Polycizer DBP; RC Plasticizer DBP; Staflex DBP; Uniflex DBP; Unimoll db; Witcizer 300; n-Butyl phthalate; o-Benzenedicarboxylic acid, dibutyl ester; [ChemIDplus] UN9095 |
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| Category |
Phthalate Esters |
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| Description |
Colorless to faint-yellow, oily liquid with a slight, aromatic odor; [NIOSH] |
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| Sources/Uses |
Plasticizer (added to polymers to effect flexibility and/or toughness); also used as an insect repellant in clothing and a solvent for perfumes, oils, and textiles; [ACGIH] Used in epoxy resins as a non-reactive solvent; [Kanerva, p. 1143] |
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| Comments |
The heated compound is an irritant to the eyes and respiratory tract. [ACGIH] Allergic contact dermatitis reported in workers handling epoxy resins; [Kanerva, p. 1143] In high-dose reproductive studies of rats and mice, DEHP and other phthalates cause testicular damage to males and increased fetal losses and malformations to pregnant females. [Frazier, p. 350-2] |
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| Reference Link |
Allergic contact dermatitis from dibutyl phthalate, propyl gallate and hydrocortisone in Timodine (No Abstract Available) |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.43 ppm |
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| PEL (OSHA) |
0.43 ppm |
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| IDLH (NIOSH) |
345 ppm |
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| Excerpts from Documentation for IDLHs |
The revised IDLH for dibutyl phthalate is 4,000 mg/m3 based on acute inhalation toxicity data in animals [Izmerov et al. 1982]. [Note: Due to its low volatility, this concentration could only be reached at elevated temperatures or if the liquid droplets become airborne as in a mist.] |
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| Vapor Pressure |
2.01 x 10 -05 mm Hg |
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| Lethal Concentration |
LC50 (mice) = 25,000 mg/m3/2H |
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| Explanatory Notes |
Flash point = 315 deg F; |
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| Half Life |
Whole body (animal studies): virtually all eliminated within 48 hours; [TDR, p. 473] |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIBUTYL PHTHALATE
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