| Disease/Syndrome |
Metalworking fluids HP |
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| Category |
Hypersensitivity Pneumonitis |
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| Acute/Chronic |
Chronic |
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| Comments |
Acute presentation: flu-like illness with cough;
Subacute: recurrent "pneumonia";
Chronic: exertional dyspnea, productive cough, and weight loss;
The exposure is to microbially contaminated, water-based metalworking fluids (MWFs) used by machinists, and the antigens are mainly Mycobacteria immunogenum; [Occupational Exposure to Metalworking Fluids, NIOSH, Publication No. 98-102; ATS/IDSA Statement: Nontuberculous Mycobacterial Diseases) Forty-four cases of MWF HP occurring in ten different plants have been confirmed by lung biopsy. Concentrations of MWF aerosols in these plants were in most cases below the current OSHA standard. Recent studies have implicated Mycobacteria immunogenum, closely related to M. chelonae, as the causal agent. Improved engineering controls are needed to reduce exposure to MWFs. [Rosenstock, p. 1043-54] See Table 1: "Diagnostic criteria for hypersensitivity pneumonitis." [Trout D, et al. Evaluation of Hypersensitivity Pneumonitis Among Workers Exposed to Metal Removal Fluids. Appl Occup Environ Hyg 2003 Nov,18(11):953-60] See "Hypersensitivity pneumonitis."
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| Latency/Incubation |
Weeks to years until "sensitized"; acute symptoms 4-12 hours after exposure; |
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| Diagnostic |
Clinical; Chest x-ray; HRCT; Pulmonary function testing; BAL; Lung biopsy; |
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| ICD-9 Code |
495.8 |
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| Reference Link |
MMWR - HP in Automobile Production Workers |
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| Related Information in Haz-Map |
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| Job Tasks |
High risk job tasks associated with this disease:
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| Agents |
Hazardous agents that cause the occupational disease:
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