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Agent Name sec-Butyl alcohol
Alternative Name sec-Butanol
CAS Number 78-92-2
Formula C4-H10-O
Major Category Solvents
Synonyms 1-Methyl propanol; 1-Methyl-1-propanol; 1-Methylpropyl alcohol; 2-Butanol (natural); 2-Butyl alcohol; 2-Hydroxybutane; Alcool butylique secondaire [French]; Butan-2-ol; Butanol secondaire [French]; Butyl alcohol, sec-; Butylene hydrate; CCS 301; Ethyl methyl carbinol; Ethylmethyl carbinol; Methyl ethyl carbinol; Methylethyl carbinol; Methylethylcarbinol; s-Butanol; s-Butyl alcohol; sec-Butanol; [ChemIDplus] UN1993
Category Alcohols and Polyols
Description Colorless liquid with a strong, pleasant odor; [NIOSH]
Sources/Uses Used as a solvent, paint remover, and cleaner; also used to manufacture other organic compounds; [ACGIH]
Comments A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 100 ppm
PEL (OSHA) 150 ppm
IDLH (NIOSH) 2000 ppm
Excerpts from Documentation for IDLHs Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by Patty [1963] that 10,670 ppm for 225 minutes and 16,000 ppm for 160 minutes were fatal for mice [Weese 1928]. According to Patty [1963], at 20,000 ppm it took 12 to 20 minutes to produce prostration in mice and 40 minutes to produce narcosis; no deaths occurred [Starrek 1938]. The chosen IDLH is probably conservative.
Vapor Pressure 18.3 mm Hg
Odor Threshold Low 0.12 ppm
Odor Threshold High 13.8 ppm
Lethal Concentration LCLo (rats) = 16,000 ppm/4H
Explanatory Notes Detection odor threshold from AIHA (mean = 3.2 ppm); Flash point = 75 deg F;
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: SEC-BUTYL ALCOHOL  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009