| Agent Name |
1,2-Dibromo-3-chloropropane |
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| Alternative Name |
DBCP |
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| CAS Number |
96-12-8 |
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| Formula |
C3-H5-Br2-Cl |
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| Major Category |
Pesticides |
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| Synonyms |
Dibromochloropropane; DBCP; [NIOSH] |
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| Category |
Fumigants |
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| Description |
Dense yellow or amber liquid with a pungent odor at high concentrations. [pesticide] [Note: A solid below 43 degrees F.] [NIOSH] |
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| Comments |
Strong positive data for testicular damage in animals and decreased sperm counts, azoospermia, and hormonal changes in humans; [ATSDR Case Studies # 29] |
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| Restricted |
All uses except on pineapple plantations in Hawaii canceled in 1979; use on pineapples cancelled in 1985; See 29CFR1910.1044; |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| PEL (OSHA) |
0.001 ppm |
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| Vapor Pressure |
0.8 mm Hg |
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| Lethal Concentration |
LC50 (rats) = 103 ppm/8H |
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| Half Life |
Animal studies: 80% of absorbed dose eliminated within 24 hours; [TDR, p. 479] |
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| Reference Link |
ATSDR - ToxFAQs - 1,2-Dibromo-3-Chloropropane |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Reproductive Toxin |
Yes |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,2-DIBROMO-3-CHLOROPROPANE
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