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Agent Name TEPP
Alternative Name Tetraethylpyrophosphate
CAS Number 107-49-3
Formula C8-H20-O7-P2
Major Category Pesticides
Synonyms Bis-O,O-diethylphosphoric anhydride; Bladan; Bladan (VAN); Diphosphoric acid tetraethyl ester; EA 1285; Ethyl pyrophosphate; Ethyl pyrophosphate (Et4P2O7); Ethyl pyrophosphate, tetra-; Fosvex; Grisol; HEPT; Hepthexamite; Hexamite; Killax; Killex; Kilmite 40; Lethalaire G-52; Lirohex; Mortopal; Nifos; Nifos T; Nifost; O,O,O,O-Tetraaethyl-diphosphat, bis(O,O-diaethylphosphorsaeure-anhydrid) [German]; O,O,O,O-Tetraethyl-difosfaat [Dutch]; O,O,O,O-Tetraetil-pirofosfato [Italian]; Pyrophosphate de tetraethyle [French]; TEPP; Tetraaethylpyrophosphorsaeureester [German]; Tetraethyl diphosphate; Tetraethyl pyrofosfaat [Belgian]; Tetraethyl pyrofosfaat [Dutch]; Tetraethyl pyrophosphate; Tetraethyldifosfat [Czech]; Tetraethylpyrofosfat [Czech]; Tetraethylpyrophosphate; Tetraethylpyrophosphorsaeureester [German]; Tetrastigmine; Tetron; Tetron-100; Vapotone; [ChemIDplus]
Category Organophosphates
Description Colorless to amber liquid with a faint, fruity odor. [insecticide] [Note: A solid below 32 degrees F.]; [NIOSH]
Sources/Uses Commercially available as dust, concentrate, or solution in methyl chloride to kill aphids, spiders, mites, mealy bugs, leafhoppers, and thirps; [ACGIH] Used on vegetable and fruit crops, it is one of the first organophosphate insecticide developed and has been largely replaced by newer products. [HSDB]
Comments Many deaths have been reported, most after suicidal ingestion. Several cases of severe poisoning and death have been reported after spills in which workers clothing was contaminated. [ACGIH]
Exposure Assessment
BEI Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]
Skin Designation (ACGIH) Yes
TLV (ACGIH) 0.01 mg/m3, inhalable fraction and vapor
PEL (OSHA) 0.05 mg/m3
MAK 0.06 mg/m3
IDLH (NIOSH) 5 mg/m3
Vapor Pressure 0.00015 mm Hg
Lethal Concentration LC50 (rats) = 7 mg/m3/4H; [ACGIH]
Adverse Effects
Other Poison Organophosphate
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: TETRAETHYL PYROPHOSPHATE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009