| Agent Name |
Methoxychlor |
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| CAS Number |
72-43-5 |
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| Formula |
C16-H15-Cl3-O2 |
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| Major Category |
Pesticides |
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| Synonyms |
1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene); 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German]; 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane; 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane; 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane; 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane; 2,2-Bis(p-anisyl)-1,1,1-trichloroethane; 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-p-anisyl-1,1,1-trichloroethane; 4,4-(2,2,2-Trichloroethylidene)dianisole; Chemform; DMDT; Dianisyl trichloroethane; Dianisyltrichlorethane; Dimethoxy-DDT; Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-; Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-; Higalmetox; Maralate; Marlate; Methoxcide; Methoxy-DDT; Methoxychlor; Methoxychlor 2 EC; Methoxychlor, technical; Methoxychlore [ISO-French]; Metoksychlor [Polish]; Metox; Mezox K; Moxie; OMS 466; p,p'-Dimethoxydiphenyltrichloroethane; p,p'-Dwumetoksydwufenylotrojchloroetan [Polish]; p,p'-Methoxychlor; [ChemIDplus] |
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| Category |
Organochlorine Pesticides |
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| Description |
Colorless to light-yellow crystals with a slight, fruity odor. [insecticide]; [NIOSH] |
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| Sources/Uses |
Used to kill insects on fruits, vegetables, and forest crops; used to kill parasites on cattle; [EXTOXNET] |
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| Comments |
Methoxychlor is classified as "practically nontoxic" with an LD50 of 5-6 gm/kg in rats. It does not accumulate in tissues of mammals, but is highly toxic to fish. It persists in the soil with a half-life estimate of 120 days. [EXTOXNET] High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 553] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414] |
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| Reference Link |
EXTOXNET PIP - METHOXYCHLOR |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| Bioaccumulates |
Yes |
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| TLV (ACGIH) |
10 mg/m3 |
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| PEL (OSHA) |
15 mg/m3, total dust |
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| MAK |
15 mg/m3, inhalable fraction |
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| IDLH (NIOSH) |
5000 mg/m3 |
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| Vapor Pressure |
2.58 x 10 -06 mm Hg |
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| Half Life |
Animal studies: most of dose eliminated within a few days;; [TDR, p. 837] |
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| Reference Link |
ATSDR - ToxFAQs - Methoxychlor |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Other Poison |
Organochlorine Pesticide |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: METHOXYCHLOR
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