| Agent Name |
1,1,2,2-Tetrabromoethane |
|---|
| Alternative Name |
Acetylene tetrabromide |
|---|
| CAS Number |
79-27-6 |
|---|
| Formula |
C2-H2-Br4 |
|---|
| Major Category |
Solvents |
|---|
| Synonyms |
Symmetrical tetrabromoethane; TBE; Tetrabromoacetylene; Tetrabromoethane; Acetylene tetrabromide; [NIOSH] Muthmann's liquid; sym-Tetrabromoethane; [ACGIH] UN2504 |
|---|
| Category |
Brominated Solvents |
|---|
| Description |
Pale-yellow liquid with a pungent odor similar to camphor or iodoform; Note: A solid below 32 degrees F; [NIOSH] |
|---|
| Sources/Uses |
Used as a solvent, ore flotation agent, catalyst, and flame-proofing additive; [ACGIH] |
|---|
| Comments |
Some animals exposed at 4 ppm for 180 days show mild lung and liver injury. One nearly fatal human case with prominent liver injury was reported. The exposure was estimated at 16 ppm for 10 minutes. Other chemicals may have been involved. Findings in another human case were that of solvent-induced encephalopathy. Direct skin contact can cause second degree burns. [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects and liver damage; [ICSC] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
0.1 ppm, inhalable fraction and vapor |
|---|
| PEL (OSHA) |
1 ppm |
|---|
| IDLH (NIOSH) |
8 ppm |
|---|
| Excerpts from Documentation for IDLHs |
Van Haaften [1969] reported that a chemist who had been exposed to 1 to 2 ppm for 7.5 hours, with only a single 10-minute exposure at 16 ppm, almost died from liver damage. |
|---|
| Vapor Pressure |
0.02 mm Hg |
|---|
| Lethal Concentration |
LC50 (rats) = 549 mg/m3/4H |
|---|
| Flammability (NFPA) |
0: will not burn |
|---|
| Adverse Effects |
|---|
| Dermatotoxin |
Skin Burns |
|---|
| Neurotoxin |
CNS Solvent Syndrome |
|---|
| Hepatotoxin |
Hepatotoxin, Primary |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,1,2,2-TETRABROMOETHANE
|
|---|
|
|
