Agent Name |
Acridine orange |
CAS Number |
65-61-2 |
Formula |
C17-H19-N3.Cl-H |
Major Category |
Dyes |
Synonyms |
3,6-Acridinediamine, N,N,N',N'-tetramethyl-,; monohydrochloride; 3,6-Bis(dimethylamino)acridine hydrochloride; Acridine Orange; Acridine Orange N; Acridine Orange NO; Acridine Orange NS; Acridine Orange R; Basic Orange 14; Basic Orange 3RN; C.I. 46005; C.I. Basic Orange 14; Rhoduline Orange; Rhoduline Orange NO; [ChemIDplus] |
Category |
Di- and Triaryl Dyes |
Sources/Uses |
"N,N,N',N'-Tetramethyl-3,6-acridinediamine, monohydrochloride. Cationic cytochemical stain specific for cell nuclei, especially DNA. It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms." [ChemIDplus] |
Comments |
Has mutagenic potential that is enhanced by light; Acridine dyes are derived from 3,6-diaminoacridine, 9-(4'-aminophenyl)-3-aminoacridine, and 9-(4'-aminophenyl)-3,6-diaminoacridine. One of the oldest acridine dyes is chrysaniline. Acridine dyes have low light fastness. In the past they were used for printing on cotton. Currently, they are not commercially important. [Ullmann] |
Adverse Effects |
IARC Carcinogen |
Not Classifiable |
Links to Other NLM Databases |
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