Agent Name |
Halothane |
CAS Number |
151-67-7 |
Formula |
C2-H-Br-Cl-F3 |
Major Category |
Other Uses |
Synonyms |
(+-)-2-Bromo-2-chloro-1,1,1-trifluoroethane; 1,1,1-Trifluoro-2-bromo-2-chloroethane; 1,1,1-Trifluoro-2-chloro-2-bromoethane; 1-Bromo-1-chloro-2,2,2-trifluoroethane; 2,2,2-Trifluoro-1-chloro-1-bromoethane; 2-Brom-2-chlor-1,1,1-trifluorethan; 2-Bromo-2-chloro-1,1,1-trifluoroethane; Alotano; Alotano [DCIT]; Anestan; Bromchlortrifluoraethanum; Bromochlorotrifluoroethane; Chalothane; Ethane, 1-bromo-1-chloro-2,2,2-trifluoro-; Ethane, 2-bromo-2-chloro-1,1,1-trifluoro-, (+-)-; Fluktan; Fluorotane; Fluothane; Freon 123B1; Ftorotan; Ftorotan [Russian]; Ftuorotan; Halan; Halotan; Halotano; Halotano [INN-Spanish]; Halothan; Halothane; Halothanum [INN-Latin]; Halsan; Narcotan; Narcotane; Narcotann NE-spofa [Russian]; Narkotan; Phthorothanum; Rhodialothan; [ChemIDplus] UN8027 |
Category |
Waste Anesthetic Gases |
Description |
Clear, colorless liquid with a sweetish, pleasant odor; inhalation anesthetic; [NIOSH] |
Sources/Uses |
Used as an anesthetic; [HSDB] |
Comments |
See "WASTE ANESTHETIC GASES" Halothane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Inhalation of high concentrations can cause CNS depression, cardiac arrhythmias, and liver injury; [ICSC] |
Reference Link |
Volatile Substance Abuse |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
50 ppm |
MAK |
5 ppm |
Vapor Pressure |
302 mm Hg |
Lethal Concentration |
LC50 (rats) = 29,000 ppm |
Explanatory Notes |
NIOSH Rel = 60 min. ceiling of 2 ppm; |
Adverse Effects |
Hepatotoxin |
Hepatotoxin, Secondary |
Reproductive Toxin |
Yes |
IARC Carcinogen |
Not Classifiable |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE
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