Agent Name |
Nitrogen chloride |
Alternative Name |
Nitrogen trichloride |
CAS Number |
10025-85-1 |
Formula |
Cl3-N |
Major Category |
Nitrogen Compounds |
Synonyms |
Agene; Chlorine nitride; Trichloramine; Trichlorine nitride; Nitrogen trichloride; [ChemIDplus] |
Category |
Other Nitrogen Compounds |
Sources/Uses |
A byproduct of water chlorination, it is volatile and strongly irritating; May make the lung more susceptible to allergens; It is formed when organic matter in sweat and urine react with chlorine in swimming pools; [Reference #2] |
Comments |
Occupational asthma in indoor pool workers (lifeguards and a swimming teacher) confirmed by specific bronchoprovocation testing; [Malo] Chloramines include chloramide (NH2Cl), dichloramide (NHCl2), and trichloramide (NCl3). Tricloramide, also called nitrogen chloride or nitrogen trichloride, was the predominant vapor found in the indoor pool environment with a high chlorine to nitrogen ratio. All three swimming pools the study had been treated with sodium hypochlorite. Measured levels of NCl3 ranged from 0.23-0.57 mg/m3 in one pool and 0.1-0.31 in another pool. The concentration used for the challenge tests was 0.5 mg/m3. All 3 workers had immediate asthmatic reactions to the challenge tests, and one had an additional late reaction. [See Reference #1] |
Reference Link |
Occupational asthma caused by chloramines in indoor swimming-pool air |
Exposure Assessment |
Lethal Concentration |
LC50 (rat) = 112 ppm/1H |
Reference Link |
The chlorine hypothesis: fact or fiction? [Occup Environ Med. 2007] - PubMed Result |
Adverse Effects |
Asthma |
Yes |
Links to Other NLM Databases |
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