| Agent Name |
m-Phenylenediamine |
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| CAS Number |
108-45-2 |
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| Formula |
C6-H8-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,3-Diaminobenzene; 1,3-Phenylenediamine; 3-Aminoaniline; Benzene, 1,3-diamino-; C.I. Developer 11; CI Developer 11; Developer 11; Developer C; Developer H; Developer M; Direct Brown BR; Direct Brown GG; Metaphenylenediamine; m-Aminoaniline; m-Benzenediamine; m-Diaminobenzene; m-Fenylendiamin [Czech]; m-Phenylenediamine; meta-Aminoaniline; meta-Benzenediamine; meta-Diaminobenzene; UN1673; [ChemIDplus] |
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| Category |
Amines, Aromatic |
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| Description |
White crystals that change to red on exposure to light and air; [CHEMINFO] |
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| Sources/Uses |
Used to make diisocyanates for the production of polyurethane foams and other resins and polymers; Also used as a corrosion inhibitor, curing agent, photographic developer, and intermediate for other chemical products; [CHEMINFO] Used to make dyes, to develop dyes, to dye hair, and to cure epoxy resins; [ACGIH] |
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| Comments |
In acute studies at lethal doses (650 mg/kg), animals have tremors, convulsions, cyanosis, and methemoglobinemia. In subchronic studies, rats have increased liver weights. "Critical Effects" are irritation; liver; Confirmed Animal Carcinogen with Unknown Relevance to Humans; [ACGIH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.1 mg/m3 |
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| Vapor Pressure |
0.0018 mm Hg |
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| Explanatory Notes |
Melting Point = 145-147 deg F; [CAMEO] |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Skin Sensitizer |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,3-BENZENEDIAMINE
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