| Agent Name |
Benzotrichloride |
|---|
| Alternative Name |
Benzyl trichloride |
|---|
| CAS Number |
98-07-7 |
|---|
| Formula |
C7-H5-Cl3 |
|---|
| Major Category |
Solvents |
|---|
| Synonyms |
1-(Trichloromethyl)benzene ; Benzene, (trichloromethyl)- ; Benzenyl trichloride ; Benzoic trichloride ; Benzotrichloride ; Benzotricloruro [Spanish] ; Benzyl trichloride ; Benzylidyne chloride ; Chlorure de benzenyle [French] ; Chlorure de benzylidyne [French] ; Phenyl chloroform ; Phenylchloroform ; Phenyltrichloromethane ; Toluene trichloride ; Toluene, alpha,alpha,alpha,-trichloro- ; Trichloormethylbenzeen [Dutch] ; Trichlormethylbenzol [German] ; Trichloromethylbenzene ; Trichlorophenylmethane ; Triclorometilbenzene [Italian] ; Triclorotoluene [Italian] ; UN2226; [ChemIDplus] |
|---|
| Category |
Chlorinated Aromatic |
|---|
| Description |
Clear to yellow liquid with a penetrating odor; [ACGIH] |
|---|
| Sources/Uses |
Used as a chemical intermediate; [ACGIH] |
|---|
| Comments |
Exposure of mice and rats to 12.5 ppm for 2 hours causes CNS excitation, eye and respiratory tract irritation, and slowed respiration. "Critical Effects" are irritation; cancer. [ACGIH] Reacts with water to form hydrochloric acid; A skin and eye irritant; In inhalation studies, 5/6 rats die after exposure of 125 ppm for 4 hours; [CHEMINFO] Burns skin, corrosive to eyes, and risk of lung edema after inhalation; [ICSC] In high-dose feeding studies of animals, mild histological changes in the liver occur. [HSDB] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
Yes |
|---|
| Ceiling (ACGIH) |
0.1 ppm |
|---|
| Vapor Pressure |
0.2 mm Hg |
|---|
| Lethal Concentration |
LC50 (rats) = 19 ppm/2H |
|---|
| Half Life |
Elimination 1/2 time of 22 hours for blood and 14 hours for tissue; [ACGIH] |
|---|
| Flammability (NFPA) |
1: must be preheated |
|---|
| Adverse Effects |
|---|
| Toxic Pneumonitis |
Yes |
|---|
| Dermatotoxin |
Skin Burns |
|---|
| Neurotoxin |
Other CNS Neurotoxin |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| IARC Carcinogen |
Probable Carcinogen |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: BENZOTRICHLORIDE
|
|---|
|
|
