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Agent Name Diesel fuel
CAS Number 68334-30-5; 68476-30-2; 68476-31-3; 68476-34-6; 77650-28-3
Major Category Solvents
Synonyms Astral oil, Gas oil, Coal oil, Fuel oil, Home heating oil, Marine diesel fuel; [ACGIH]
Category Refined Petroleum
Description Brown to straw-colored liquids; [ACGIH] A mixture of aliphatic, olefinic, naphthenic, and aromatic hydrocarbons; [CHEMINFO MSDS]
Sources/Uses Used for heating oil and diesel engines; [CHEMINFO MSDS]
Comments Critical Effects: skin; irritation; "Avoid prolonged and repeated skin contact to diesel fuels which can lead to dermal irritation and may be associated with and increased risk of skin cancer." Diesel fuel does not contain significant levels of polynuclear aromatics (PNAs) and contains <0.01% benzene and n-hexane. Rats and mice exposed repeatedly to high doses show evidence of liver damage. IARC classified marine diesel fuel as 2B (possible human carcinogen) and exposures in petroleum refineries as 2A (probable carcinogen). A few cases of acute renal failure following diesel exposure have been reported. [ACGIH] Excessive inhalation can cause CNS depression and heartbeat irregularities; [CHEMINFO MSDS] Acute tubular necrosis has been reported after heavy skin exposure, e.g., frequent hand washing with diesel oil over several weeks. [Rosenstock]
Exposure Assessment
Skin Designation (ACGIH) Yes
TLV (ACGIH) 100 mg/m3, as total hydrocarbons (inhalable fraction and vapor)
Vapor Pressure 2.1 mm Hg
Explanatory Notes VP = 2.1 to 2.6 torr @ 21 degrees C; [ACGIH]
Flammability (NFPA) 2: high ambient temperature required
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Hepatotoxin Hepatotoxin, Secondary
Nephrotoxin Yes
IARC Carcinogen Possible Carcinogen
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: Diesel fuel  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009