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Agent Name Isobutyronitrile
CAS Number 78-82-0
Formula C4-H7-N
Major Category Toxic Gases & Vapors
Synonyms 1-Cyano-1-methylethane; 2-Cyanopropane; 2-Methylpropane nitrile; 2-ethylpropanenitrile; 2-Methylpropionitrile; Dimethylacetonitrile; Isobutyronitrile; Isopropyl cyanide; Isopropyl nitrile; Isopropylkyanid [Czech]; Isopropylnitrile; Propanenitrile, 2-methyl-; Propanoic acid, 2-methyl-, nitrile; alpha-Methylpropanenitrile; [ChemIDplus] UN2284
Category Nitriles
Description Colorless liquid with an almond-like odor; Note: Forms cyanide in the body; [NIOSH]
Sources/Uses Used in the synthesis of insecticides and gasoline additives; used as a catalyst in the production of polyethylene; [HSDB]
Comments Isobutyronitrile is hazardous by the oral, skin, or inhalation routes; it causes liver injury in animal feeding studies. Animals inhaling 5500 ppm for one hour have convulsions and die. [HSDB]
Exposure Assessment
Skin Designation (ACGIH) Not evaluated
Vapor Pressure 32.7 mm Hg
Lethal Concentration LCLo (rats) = 1,000 ppm/4h
Explanatory Notes NIOSH REL = 8 ppm; Flash point = 8 deg C;
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Hepatotoxin Hepatotoxin, Secondary
Other Poison Chemical Asphyxiant
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: 2-METHYLPROPANENITRILE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Other InformationNo other related information on this agent was found.





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Last updated: January, 2009