| Agent Name |
Methyl propyl ketone |
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| Alternative Name |
2-Pentanone |
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| CAS Number |
107-87-9 |
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| Formula |
C5-H10-O |
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| Major Category |
Solvents |
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| Synonyms |
2-Pentanone (natural); Ethyl acetone; Ethylacetone; Methyl n-propyl ketone; Methyl propyl ketone; Methyl-propyl-cetone [French]; Methylpropyl ketone; Metylopropyloketon [Polish]; Propyl methyl ketone; MPK; [ChemIDplus] UN1249 |
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| Category |
Ketones |
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| Description |
Colorless to water-white liquid with a characteristic acetone-like odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent, a flavoring agent, and in organic synthesis; [ACGIH] Used as a solvent for lacquers and surface coatings; [HSDB] |
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| Comments |
Causes CNS depression and fatty degeneration of the liver after inhalation of high doses by experimental animals; A respiratory tract irritant; [ACGIH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| STEL (ACGIH) |
150 ppm |
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| PEL (OSHA) |
200 ppm |
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| IDLH (NIOSH) |
1500 ppm |
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| Excerpts from Documentation for IDLHs |
Exposure to a concentration of 1,500 ppm was associated with complaints of ocular and upper respiratory irritation [Yant et al. 1936]. |
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| Vapor Pressure |
35.4 mm Hg |
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| Odor Threshold Low |
3.1 ppm |
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| Odor Threshold High |
13.6 ppm |
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| RD50 |
12832 ppm |
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| Lethal Concentration |
LCLo (rats) = 2,000 ppm/4H |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 7.7 ppm); Flash point equals 7 deg C; [ACGIH] |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: METHYL PROPYL KETONE
|
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